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Results: 20

1.

IL-6 pathway-driven investigation of response to IL-6 receptor inhibition in rheumatoid arthritis.

Wang J, Platt A, Upmanyu R, Germer S, Lei G, Rabe C, Benayed R, Kenwright A, Hemmings A, Martin M, Harari O.

BMJ Open. 2013 Aug 19;3(8):e003199. doi: 10.1136/bmjopen-2013-003199.

PMID:
23959753
[PubMed]
Free PMC Article
2.

Novel genetically-humanized mouse model established to evaluate efficacy of therapeutic agents to human interleukin-6 receptor.

Ueda O, Tateishi H, Higuchi Y, Fujii E, Kato A, Kawase Y, Wada NA, Tachibe T, Kakefuda M, Goto C, Kawaharada M, Shimaoka S, Hattori K, Jishage K.

Sci Rep. 2013;3:1196. doi: 10.1038/srep01196. Epub 2013 Feb 1.

PMID:
23378927
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Interleukin-6 receptor polymorphism is prevalent in HIV-negative Castleman Disease and is associated with increased soluble interleukin-6 receptor levels.

Stone K, Woods E, Szmania SM, Stephens OW, Garg TK, Barlogie B, Shaughnessy JD Jr, Hall B, Reddy M, Hoering A, Hansen E, van Rhee F.

PLoS One. 2013;8(1):e54610. doi: 10.1371/journal.pone.0054610. Epub 2013 Jan 23.

PMID:
23372742
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of IL-6 in asthma and other inflammatory pulmonary diseases.

Rincon M, Irvin CG.

Int J Biol Sci. 2012;8(9):1281-90. doi: 10.7150/ijbs.4874. Epub 2012 Oct 25. Review.

PMID:
23136556
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Interleukin-6 receptor pathways in abdominal aortic aneurysm.

Harrison SC, Smith AJ, Jones GT, Swerdlow DI, Rampuri R, Bown MJ; Aneurysm Consortium, Folkersen L, Baas AF, de Borst GJ, Blankensteijn JD, Price JF, van der Graaf Y, McLachlan S, Agu O, Hofman A, Uitterlinden AG, Franco-Cereceda A, Ruigrok YM, van't Hof FN, Powell JT, van Rij AM, Casas JP, Eriksson P, Holmes MV, Asselbergs FW, Hingorani AD, Humphries SE.

Eur Heart J. 2013 Dec;34(48):3707-16. doi: 10.1093/eurheartj/ehs354. Epub 2012 Oct 30. Review.

PMID:
23111417
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Genetic markers of cardiovascular disease in rheumatoid arthritis.

Rodríguez-Rodríguez L, López-Mejías R, García-Bermúdez M, González-Juanatey C, González-Gay MA, Martín J.

Mediators Inflamm. 2012;2012:574817. doi: 10.1155/2012/574817. Epub 2012 Aug 2. Review.

PMID:
22927710
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The IL6R variation Asp(358)Ala is a potential modifier of lung function in subjects with asthma.

Hawkins GA, Robinson MB, Hastie AT, Li X, Li H, Moore WC, Howard TD, Busse WW, Erzurum SC, Wenzel SE, Peters SP, Meyers DA, Bleecker ER; National Heart, Lung, and Blood Institute–sponsored Severe Asthma Research Program (SARP).

J Allergy Clin Immunol. 2012 Aug;130(2):510-5.e1. doi: 10.1016/j.jaci.2012.03.018. Epub 2012 May 1.

PMID:
22554704
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium, Hingorani AD, Casas JP.

Lancet. 2012 Mar 31;379(9822):1214-24. doi: 10.1016/S0140-6736(12)60110-X. Epub 2012 Mar 14.

PMID:
22421340
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

An intermediate-risk multiple myeloma subgroup is defined by sIL-6r: levels synergistically increase with incidence of SNP rs2228145 and 1q21 amplification.

Stephens OW, Zhang Q, Qu P, Zhou Y, Chavan S, Tian E, Williams DR, Epstein J, Barlogie B, Shaughnessy JD Jr.

Blood. 2012 Jan 12;119(2):503-12. doi: 10.1182/blood-2011-07-367052. Epub 2011 Nov 9.

PMID:
22072558
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Population differences in proinflammatory biology: Japanese have healthier profiles than Americans.

Coe CL, Love GD, Karasawa M, Kawakami N, Kitayama S, Markus HR, Tracy RP, Ryff CD.

Brain Behav Immun. 2011 Mar;25(3):494-502. doi: 10.1016/j.bbi.2010.11.013. Epub 2010 Nov 26.

PMID:
21112385
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

High habitual dietary alpha-linolenic acid intake is associated with decreased plasma soluble interleukin-6 receptor concentrations in male twins.

Dai J, Ziegler TR, Bostick RM, Manatunga AK, Jones DP, Goldberg J, Miller A, Vogt G, Wilson PW, Jones L, Shallenberger L, Vaccarino V.

Am J Clin Nutr. 2010 Jul;92(1):177-85. doi: 10.3945/ajcn.2010.29305. Epub 2010 May 12.

PMID:
20463041
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor).

Lagmay JP, London WB, Gross TG, Termuhlen A, Sullivan N, Axel A, Mundy B, Ranalli M, Canner J, McGrady P, Hall B.

Clin Cancer Res. 2009 Aug 15;15(16):5234-9. doi: 10.1158/1078-0432.CCR-08-2953. Epub 2009 Aug 11.

PMID:
19671870
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genetic ancestry modifies pharmacogenetic gene-gene interaction for asthma.

Corvol H, De Giacomo A, Eng C, Seibold M, Ziv E, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Thyne S, Watson HG, Meade K, LeNoir M, Avila PC, Choudhry S, Burchard EG; Genetics of Asthma in Latino Americans (GALA) Study; Study of African-Americans, Asthma, Genes and Environments (SAGE) Investigators.

Pharmacogenet Genomics. 2009 Jul;19(7):489-96. doi: 10.1097/FPC.0b013e32832c440e.

PMID:
19503017
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Inflammation and stress-related candidate genes, plasma interleukin-6 levels, and longevity in older adults.

Walston JD, Matteini AM, Nievergelt C, Lange LA, Fallin DM, Barzilai N, Ziv E, Pawlikowska L, Kwok P, Cummings SR, Kooperberg C, LaCroix A, Tracy RP, Atzmon G, Lange EM, Reiner AP.

Exp Gerontol. 2009 May;44(5):350-5. doi: 10.1016/j.exger.2009.02.004. Epub 2009 Feb 26.

PMID:
19249341
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma.

Birmann BM, Tamimi RM, Giovannucci E, Rosner B, Hunter DJ, Kraft P, Mitsiades C, Anderson KC, Colditz GA.

Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):282-8. doi: 10.1158/1055-9965.EPI-08-0778.

PMID:
19124510
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Gene variants influencing measures of inflammation or predisposing to autoimmune and inflammatory diseases are not associated with the risk of type 2 diabetes.

Rafiq S, Melzer D, Weedon MN, Lango H, Saxena R, Scott LJ; DIAGRAM Consortium, Palmer CN, Morris AD, McCarthy MI, Ferrucci L, Hattersley AT, Zeggini E, Frayling TM.

Diabetologia. 2008 Dec;51(12):2205-13. doi: 10.1007/s00125-008-1160-3. Epub 2008 Oct 14.

PMID:
18853133
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Interleukin and interleukin receptor gene polymorphisms and susceptibility to melanoma.

Gu F, Qureshi AA, Niu T, Kraft P, Guo Q, Hunter DJ, Han J.

Melanoma Res. 2008 Oct;18(5):330-5. doi: 10.1097/CMR.0b013e32830658b2.

PMID:
18781131
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

Rafiq S, Frayling TM, Murray A, Hurst A, Stevens K, Weedon MN, Henley W, Ferrucci L, Bandinelli S, Corsi AM, Guralnik JM, Melzer D.

Genes Immun. 2007 Oct;8(7):552-9. Epub 2007 Aug 2.

PMID:
17671508
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Cancer-related fatigue: links with inflammation in cancer patients and survivors.

Bower JE.

Brain Behav Immun. 2007 Oct;21(7):863-71. Epub 2007 May 31. Review.

PMID:
17543499
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels.

Reich D, Patterson N, Ramesh V, De Jager PL, McDonald GJ, Tandon A, Choy E, Hu D, Tamraz B, Pawlikowska L, Wassel-Fyr C, Huntsman S, Waliszewska A, Rossin E, Li R, Garcia M, Reiner A, Ferrell R, Cummings S, Kwok PY, Harris T, Zmuda JM, Ziv E; Health, Aging and Body Composition (Health ABC) Study.

Am J Hum Genet. 2007 Apr;80(4):716-26. Epub 2007 Mar 8.

PMID:
17357077
[PubMed - indexed for MEDLINE]
Free PMC Article

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