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Results: 1 to 20 of 60

1.

Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan.

Schaar CE, Dues DJ, Spielbauer KK, Machiela E, Cooper JF, Senchuk M, Hekimi S, Van Raamsdonk JM.

PLoS Genet. 2015 Feb 11;11(2):e1004972. doi: 10.1371/journal.pgen.1004972. eCollection 2015 Feb.

PMID:
25671321
[PubMed - in process]
Free PMC Article
2.

Prohibitin-Mediated Lifespan and Mitochondrial Stress Implicate SGK-1, Insulin/IGF and mTORC2 in C. elegans.

Gatsi R, Schulze B, Rodríguez-Palero MJ, Hernando-Rodríguez B, Baumeister R, Artal-Sanz M.

PLoS One. 2014 Sep 29;9(9):e107671. doi: 10.1371/journal.pone.0107671. eCollection 2014.

PMID:
25265021
[PubMed - in process]
Free PMC Article
3.

Mitochondrial stress signaling in longevity: a new role for mitochondrial function in aging.

Hill S, Van Remmen H.

Redox Biol. 2014 Jul 27;2:936-44. doi: 10.1016/j.redox.2014.07.005. eCollection 2014.

PMID:
25180170
[PubMed - in process]
Free PMC Article
4.

D-beta-hydroxybutyrate extends lifespan in C. elegans.

Edwards C, Canfield J, Copes N, Rehan M, Lipps D, Bradshaw PC.

Aging (Albany NY). 2014 Aug;6(8):621-44.

PMID:
25127866
[PubMed - in process]
Free PMC Article
5.

Mitohormesis: Promoting Health and Lifespan by Increased Levels of Reactive Oxygen Species (ROS).

Ristow M, Schmeisser K.

Dose Response. 2014 Jan 31;12(2):288-341. doi: 10.2203/dose-response.13-035.Ristow. eCollection 2014 May.

PMID:
24910588
[PubMed]
Free PMC Article
6.

Activation of the endoplasmic reticulum unfolded protein response by lipid disequilibrium without disturbed proteostasis in vivo.

Hou NS, Gutschmidt A, Choi DY, Pather K, Shi X, Watts JL, Hoppe T, Taubert S.

Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2271-80. doi: 10.1073/pnas.1318262111. Epub 2014 May 19.

PMID:
24843123
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Quality control in mitochondria: use it, break it, fix it, trash it.

Kornmann B.

F1000Prime Rep. 2014 Mar 3;6:15. doi: 10.12703/P6-15. eCollection 2014. Review.

PMID:
24669296
[PubMed]
Free PMC Article
8.

Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans.

Bennett CF, Vander Wende H, Simko M, Klum S, Barfield S, Choi H, Pineda VV, Kaeberlein M.

Nat Commun. 2014 Mar 24;5:3483. doi: 10.1038/ncomms4483.

PMID:
24662282
[PubMed - in process]
Free PMC Article
9.

Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome.

Liang V, Ullrich M, Lam H, Chew YL, Banister S, Song X, Zaw T, Kassiou M, Götz J, Nicholas HR.

Cell Mol Life Sci. 2014 Sep;71(17):3339-61. doi: 10.1007/s00018-014-1558-7. Epub 2014 Jan 24.

PMID:
24458371
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Mitochondrial dysfunction, oxidative stress, and neurodegeneration elicited by a bacterial metabolite in a C. elegans Parkinson's model.

Ray A, Martinez BA, Berkowitz LA, Caldwell GA, Caldwell KA.

Cell Death Dis. 2014 Jan 9;5:e984. doi: 10.1038/cddis.2013.513.

PMID:
24407237
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The mitochondrial unfolded protein response, a conserved stress response pathway with implications in health and disease.

Jovaisaite V, Mouchiroud L, Auwerx J.

J Exp Biol. 2014 Jan 1;217(Pt 1):137-43. doi: 10.1242/jeb.090738. Review.

PMID:
24353213
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Regulation of autophagy by LRRK2 in Caenorhabditis elegans.

Saha S, Liu-Yesucevitz L, Wolozin B.

Neurodegener Dis. 2014;13(2-3):110-3. doi: 10.1159/000355654. Epub 2013 Oct 31.

PMID:
24192129
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.

Mouchiroud L, Houtkooper RH, Moullan N, Katsyuba E, Ryu D, Cantó C, Mottis A, Jo YS, Viswanathan M, Schoonjans K, Guarente L, Auwerx J.

Cell. 2013 Jul 18;154(2):430-41. doi: 10.1016/j.cell.2013.06.016.

PMID:
23870130
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Molecular mechanisms underlying genotype-dependent responses to dietary restriction.

Schleit J, Johnson SC, Bennett CF, Simko M, Trongtham N, Castanza A, Hsieh EJ, Moller RM, Wasko BM, Delaney JR, Sutphin GL, Carr D, Murakami CJ, Tocchi A, Xian B, Chen W, Yu T, Goswami S, Higgins S, Holmberg M, Jeong KS, Kim JR, Klum S, Liao E, Lin MS, Lo W, Miller H, Olsen B, Peng ZJ, Pollard T, Pradeep P, Pruett D, Rai D, Ros V, Singh M, Spector BL, Vander Wende H, An EH, Fletcher M, Jelic M, Rabinovitch PS, MacCoss MJ, Han JD, Kennedy BK, Kaeberlein M.

Aging Cell. 2013 Dec;12(6):1050-61. doi: 10.1111/acel.12130. Epub 2013 Aug 11.

PMID:
23837470
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A cytoprotective perspective on longevity regulation.

Shore DE, Ruvkun G.

Trends Cell Biol. 2013 Sep;23(9):409-20. doi: 10.1016/j.tcb.2013.04.007. Epub 2013 May 30. Review.

PMID:
23726168
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Mitonuclear protein imbalance as a conserved longevity mechanism.

Houtkooper RH, Mouchiroud L, Ryu D, Moullan N, Katsyuba E, Knott G, Williams RW, Auwerx J.

Nature. 2013 May 23;497(7450):451-7. doi: 10.1038/nature12188.

PMID:
23698443
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Identification of a tissue-selective heat shock response regulatory network.

Guisbert E, Czyz DM, Richter K, McMullen PD, Morimoto RI.

PLoS Genet. 2013 Apr;9(4):e1003466. doi: 10.1371/journal.pgen.1003466. Epub 2013 Apr 18.

PMID:
23637632
[PubMed - in process]
Free PMC Article
18.

Mitochondria and organismal longevity.

Hwang AB, Jeong DE, Lee SJ.

Curr Genomics. 2012 Nov;13(7):519-32. doi: 10.2174/138920212803251427.

PMID:
23633912
[PubMed]
Free PMC Article
19.

Genome-Wide RNAi Longevity Screens in Caenorhabditis elegans.

Yanos ME, Bennett CF, Kaeberlein M.

Curr Genomics. 2012 Nov;13(7):508-18. doi: 10.2174/138920212803251391.

PMID:
23633911
[PubMed]
Free PMC Article
20.

Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant.

Pujol C, Bratic-Hench I, Sumakovic M, Hench J, Mourier A, Baumann L, Pavlenko V, Trifunovic A.

PLoS One. 2013;8(3):e59493. doi: 10.1371/journal.pone.0059493. Epub 2013 Mar 28.

PMID:
23555681
[PubMed - indexed for MEDLINE]
Free PMC Article
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