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Results: 1 to 20 of 28

1.

Towards the clinical implementation of pharmacogenetics in bipolar disorder.

Salloum NC, McCarthy MJ, Leckband SG, Kelsoe JR.

BMC Med. 2014 May 30;12:90. doi: 10.1186/1741-7015-12-90.

PMID:
24885933
[PubMed - in process]
Free PMC Article
2.

Imputation of TPMT defective alleles for the identification of patients with high-risk phenotypes.

Almoguera B, Vazquez L, Connolly JJ, Bradfield J, Sleiman P, Keating B, Hakonarson H.

Front Genet. 2014 May 12;5:96. doi: 10.3389/fgene.2014.00096. eCollection 2014.

PMID:
24860591
[PubMed]
Free PMC Article
3.

Thiopurine methyltransferase genotype and thiopurine S-methyltransferase activity in Greek children with inflammatory bowel disease.

Gazouli M, Pachoula I, Panayotou I, Chouliaras G, Anagnou NP, Chroussos G, Roma E.

Ann Gastroenterol. 2012;25(3):249-253.

PMID:
24714152
[PubMed - as supplied by publisher]
Free PMC Article
4.

Advances in the diagnosis and management of inflammatory bowel disease: challenges and uncertainties.

Mosli M, Al Beshir M, Al-Judaibi B, Al-Ameel T, Saleem A, Bessissow T, Ghosh S, Almadi M.

Saudi J Gastroenterol. 2014 Mar-Apr;20(2):81-101. doi: 10.4103/1319-3767.129473.

PMID:
24705146
[PubMed - in process]
Free PMC Article
5.

Phenome-wide association studies on a quantitative trait: application to TPMT enzyme activity and thiopurine therapy in pharmacogenomics.

Neuraz A, Chouchana L, Malamut G, Le Beller C, Roche D, Beaune P, Degoulet P, Burgun A, Loriot MA, Avillach P.

PLoS Comput Biol. 2013;9(12):e1003405. doi: 10.1371/journal.pcbi.1003405. Epub 2013 Dec 26.

PMID:
24385893
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Monitoring and safety of azathioprine therapy in inflammatory bowel disease.

Kim MJ, Choe YH.

Pediatr Gastroenterol Hepatol Nutr. 2013 Jun;16(2):65-70. doi: 10.5223/pghn.2013.16.2.65. Epub 2013 Jun 30. Review.

PMID:
24010109
[PubMed]
Free PMC Article
7.

Thiopurines in inflammatory bowel disease revisited.

Bär F, Sina C, Fellermann K.

World J Gastroenterol. 2013 Mar 21;19(11):1699-706. doi: 10.3748/wjg.v19.i11.1699. Review.

PMID:
23555158
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Nomenclature for alleles of the thiopurine methyltransferase gene.

Appell ML, Berg J, Duley J, Evans WE, Kennedy MA, Lennard L, Marinaki T, McLeod HL, Relling MV, Schaeffeler E, Schwab M, Weinshilboum R, Yeoh AE, McDonagh EM, Hebert JM, Klein TE, Coulthard SA.

Pharmacogenet Genomics. 2013 Apr;23(4):242-8. doi: 10.1097/FPC.0b013e32835f1cc0.

PMID:
23407052
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Thiopurine methyltransferase genotype-phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia.

Lennard L, Cartwright CS, Wade R, Richards SM, Vora A.

Br J Clin Pharmacol. 2013 Jul;76(1):125-36. doi: 10.1111/bcp.12066.

PMID:
23252716
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Thiopurine methyltransferase predicts the extent of cytotoxicty and DNA damage in astroglial cells after thioguanine exposure.

Hosni-Ahmed A, Barnes JD, Wan J, Jones TS.

PLoS One. 2011;6(12):e29163. doi: 10.1371/journal.pone.0029163. Epub 2011 Dec 21.

PMID:
22216194
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Two brothers with skewed thiopurine metabolism in ulcerative colitis treated successfully with allopurinol and mercaptopurine dose reduction.

Hoentjen F, Hanauer SB, de Boer NK, Rubin DT.

Dig Dis Sci. 2012 Jan;57(1):250-3. doi: 10.1007/s10620-011-1999-x. Epub 2011 Dec 7.

PMID:
22147254
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Recent progress and clinical importance on pharmacogenetics in cancer therapy.

Soh TI, Yong WP, Innocenti F.

Clin Chem Lab Med. 2011 Oct;49(10):1621-32. doi: 10.1515/CCLM.2011.715. Epub 2011 Sep 28. Review.

PMID:
21950596
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Part 3: Pharmacogenetic variability in phase II anticancer drug metabolism.

Deenen MJ, Cats A, Beijnen JH, Schellens JH.

Oncologist. 2011;16(7):992-1005. doi: 10.1634/theoncologist.2010-0260. Epub 2011 Jun 9. Review.

PMID:
21659608
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Clinical Pharmacogenetics Implementation Consortium guidelines for thiopurine methyltransferase genotype and thiopurine dosing.

Relling MV, Gardner EE, Sandborn WJ, Schmiegelow K, Pui CH, Yee SW, Stein CM, Carrillo M, Evans WE, Klein TE; Clinical Pharmacogenetics Implementation Consortium.

Clin Pharmacol Ther. 2011 Mar;89(3):387-91. doi: 10.1038/clpt.2010.320. Epub 2011 Jan 26. Erratum in: Clin Pharmacol Ther. 2011 Dec;90(6):894.

PMID:
21270794
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Influence of 5-aminosalicylic acid on 6-thioguanosine phosphate metabolite levels: a prospective study in patients under steady thiopurine therapy.

de Graaf P, de Boer NK, Wong DR, Karner S, Jharap B, Hooymans PM, Veldkamp AI, Mulder CJ, van Bodegraven AA, Schwab M.

Br J Pharmacol. 2010 Jul;160(5):1083-91. doi: 10.1111/j.1476-5381.2010.00731.x.

PMID:
20590602
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Very important pharmacogene summary: thiopurine S-methyltransferase.

Wang L, Pelleymounter L, Weinshilboum R, Johnson JA, Hebert JM, Altman RB, Klein TE.

Pharmacogenet Genomics. 2010 Jun;20(6):401-5. doi: 10.1097/FPC.0b013e3283352860. Review. No abstract available.

PMID:
20154640
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Thiopurine S-methyltransferase pharmacogenetics: functional characterization of a novel rapidly degraded variant allozyme.

Feng Q, Vannaprasaht S, Peng Y, Angsuthum S, Avihingsanon Y, Yee VC, Tassaneeyakul W, Weinshilboum RM.

Biochem Pharmacol. 2010 Apr 1;79(7):1053-61. doi: 10.1016/j.bcp.2009.11.016. Epub 2009 Nov 27.

PMID:
19945438
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Perioperative genomic profiles using structure-specific oligonucleotide probes.

Hogan KJ, Burmester JK, Caldwell MD, Hogan QH, Coursin DB, Green DN, Selzer RM, Broderick TP, Rusy DA, Poroli M, Lutz AL, Sanders AM, Oldenburg MC, Koelbl JA, de Arruda-Indig M, Halsey JL, Day SP, Domanico MJ.

Clin Med Res. 2009 Sep;7(3):69-84. doi: 10.3121/cmr.2009.837. Epub 2009 May 27.

PMID:
19474452
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Pharmacogenetics and pharmacogenomics of anticancer agents.

Huang RS, Ratain MJ.

CA Cancer J Clin. 2009 Jan-Feb;59(1):42-55. doi: 10.3322/caac.20002. Review.

PMID:
19147868
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

TPMT genetic variations in populations of the Russian Federation.

Samochatova EV, Chupova NV, Rudneva A, Makarova O, Nasedkina TV, Fedorova OE, Glotov AS, Kozhekbaeva Zh, Maiorova OA, Roumyantsev AG, Krynetski EY, Krynetskaia NF, Evans WE, Ribeiro RC.

Pediatr Blood Cancer. 2009 Feb;52(2):203-8. doi: 10.1002/pbc.21837.

PMID:
19034904
[PubMed - indexed for MEDLINE]
Free PMC Article

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