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Items: 12


mTOR Directs Breast Morphogenesis through the PKC-alpha-Rac1 Signaling Axis.

Morrison MM, Young CD, Wang S, Sobolik T, Sanchez VM, Hicks DJ, Cook RS, Brantley-Sieders DM.

PLoS Genet. 2015 Jul 1;11(7):e1005291. doi: 10.1371/journal.pgen.1005291. eCollection 2015 Jul.


The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development.

Schäker K, Bartsch S, Patry C, Stoll SJ, Hillebrands JL, Wieland T, Kroll J.

J Biol Chem. 2015 Mar 6;290(10):6408-18. doi: 10.1074/jbc.M114.633701. Epub 2015 Jan 13.


Mislocalization of death receptors correlates with cellular resistance to their cognate ligands in human breast cancer cells.

Chen JJ, Shen HC, Rivera Rosado LA, Zhang Y, Di X, Zhang B.

Oncotarget. 2012 Aug;3(8):833-42.


Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis.

Osborn-Heaford HL, Ryan AJ, Murthy S, Racila AM, He C, Sieren JC, Spitz DR, Carter AB.

J Biol Chem. 2012 Jan 27;287(5):3301-12. doi: 10.1074/jbc.M111.308387. Epub 2011 Dec 8.


p21-Activated kinase 1 (Pak1) phosphorylates BAD directly at serine 111 in vitro and indirectly through Raf-1 at serine 112.

Ye DZ, Jin S, Zhuo Y, Field J.

PLoS One. 2011;6(11):e27637. doi: 10.1371/journal.pone.0027637. Epub 2011 Nov 11.


RhoA protects the mouse heart against ischemia/reperfusion injury.

Xiang SY, Vanhoutte D, Del Re DP, Purcell NH, Ling H, Banerjee I, Bossuyt J, Lang RA, Zheng Y, Matkovich SJ, Miyamoto S, Molkentin JD, Dorn GW 2nd, Brown JH.

J Clin Invest. 2011 Aug;121(8):3269-76. doi: 10.1172/JCI44371. Epub 2011 Jul 11.


The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain.

Leone DP, Srinivasan K, Brakebusch C, McConnell SK.

Dev Neurobiol. 2010 Aug;70(9):659-78. doi: 10.1002/dneu.20804.


Rac1 targeting suppresses p53 deficiency-mediated lymphomagenesis.

Bosco EE, Ni W, Wang L, Guo F, Johnson JF, Zheng Y.

Blood. 2010 Apr 22;115(16):3320-8. doi: 10.1182/blood-2009-02-202440. Epub 2010 Feb 23.


Silencing of D4-GDI inhibits growth and invasive behavior in MDA-MB-231 cells by activation of Rac-dependent p38 and JNK signaling.

Zhang Y, Rivera Rosado LA, Moon SY, Zhang B.

J Biol Chem. 2009 May 8;284(19):12956-65. doi: 10.1074/jbc.M807845200. Epub 2009 Mar 6.


The small GTPase RhoH is an atypical regulator of haematopoietic cells.

Fueller F, Kubatzky KF.

Cell Commun Signal. 2008 Sep 29;6:6. doi: 10.1186/1478-811X-6-6.


Cytotoxic necrotizing factor 1 prevents apoptosis via the Akt/IkappaB kinase pathway: role of nuclear factor-kappaB and Bcl-2.

Miraglia AG, Travaglione S, Meschini S, Falzano L, Matarrese P, Quaranta MG, Viora M, Fiorentini C, Fabbri A.

Mol Biol Cell. 2007 Jul;18(7):2735-44. Epub 2007 May 16.


RhoGTPases and p53 are involved in the morphological appearance and interferon-alpha response of hairy cells.

Chaigne-Delalande B, Deuve L, Reuzeau E, Basoni C, Lafarge D, Varon C, Tatin F, Anies G, Garand R, Kramer I, Génot E.

Am J Pathol. 2006 Feb;168(2):562-73.

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