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HIV-1 Subtype C Mosaic Gag Expressed by BCG and MVA Elicits Persistent Effector T Cell Responses in a Prime-Boost Regimen in Mice.

Jongwe TI, Chapman R, Douglass N, Chetty S, Chege G, Williamson AL.

PLoS One. 2016 Jul 18;11(7):e0159141. doi: 10.1371/journal.pone.0159141. eCollection 2016.


Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection.

Sun J, Schaaf K, Duverger A, Wolschendorf F, Speer A, Wagner F, Niederweis M, Kutsch O.

Oncotarget. 2016 Mar 29;7(13):15394-409. doi: 10.18632/oncotarget.8190.


Vaccine-mediated immunity to experimental Mycobacterium tuberculosis is not impaired in the absence of Toll-like receptor 9.

Gopalakrishnan A, Dietzold J, Salgame P.

Cell Immunol. 2016 Apr;302:11-8. doi: 10.1016/j.cellimm.2015.12.009. Epub 2015 Dec 30.


Gene Transfer in Mycobacterium tuberculosis: Shuttle Phasmids to Enlightenment.

Jacobs WR Jr.

Microbiol Spectr. 2014 Apr;2(2). doi: 10.1128/microbiolspec.MGM2-0037-2013. Review.


The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems.

Nambi S, Long JE, Mishra BB, Baker R, Murphy KC, Olive AJ, Nguyen HP, Shaffer SA, Sassetti CM.

Cell Host Microbe. 2015 Jun 10;17(6):829-37. doi: 10.1016/j.chom.2015.05.008.


Stable Expression of Lentiviral Antigens by Quality-Controlled Recombinant Mycobacterium bovis BCG Vectors.

Hart BE, Asrican R, Lim SY, Sixsmith JD, Lukose R, Souther SJ, Rayasam SD, Saelens JW, Chen CJ, Seay SA, Berney-Meyer L, Magtanong L, Vermeul K, Pajanirassa P, Jimenez AE, Ng TW, Tobin DM, Porcelli SA, Larsen MH, Schmitz JE, Haynes BF, Jacobs WR Jr, Lee S, Frothingham R.

Clin Vaccine Immunol. 2015 Jul;22(7):726-41. doi: 10.1128/CVI.00075-15. Epub 2015 Apr 29.


Zinc regulates a switch between primary and alternative S18 ribosomal proteins in Mycobacterium tuberculosis.

Prisic S, Hwang H, Dow A, Barnaby O, Pan TS, Lonzanida JA, Chazin WJ, Steen H, Husson RN.

Mol Microbiol. 2015 Jul;97(2):263-80. doi: 10.1111/mmi.13022. Epub 2015 May 15.


Tuberculosis vaccine types and timings.

Orme IM.

Clin Vaccine Immunol. 2015 Mar;22(3):249-57. doi: 10.1128/CVI.00718-14. Epub 2014 Dec 24. Review.


Generation and screening of a comprehensive Mycobacterium avium subsp. paratuberculosis transposon mutant bank.

Rathnaiah G, Lamont EA, Harris NB, Fenton RJ, Zinniel DK, Liu X, Sotos J, Feng Z, Livneh-Kol A, Shpigel NY, Czuprynski CJ, Sreevatsan S, Barletta RG.

Front Cell Infect Microbiol. 2014 Oct 15;4:144. doi: 10.3389/fcimb.2014.00144. eCollection 2014.


Subpolar addition of new cell wall is directed by DivIVA in mycobacteria.

Meniche X, Otten R, Siegrist MS, Baer CE, Murphy KC, Bertozzi CR, Sassetti CM.

Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):E3243-51. doi: 10.1073/pnas.1402158111. Epub 2014 Jul 21.


Mycobacterial gene cuvA is required for optimal nutrient utilization and virulence.

Mir M, Prisic S, Kang CM, Lun S, Guo H, Murry JP, Rubin EJ, Husson RN.

Infect Immun. 2014 Oct;82(10):4104-17. doi: 10.1128/IAI.02207-14. Epub 2014 Jul 21.


Dietary pyridoxine controls efficacy of vitamin B6-auxotrophic tuberculosis vaccine bacillus Calmette-Guérin ΔureC::hly Δpdx1 in mice.

Gengenbacher M, Vogelzang A, Schuerer S, Lazar D, Kaiser P, Kaufmann SH.

MBio. 2014 Jun 3;5(3):e01262-14. doi: 10.1128/mBio.01262-14.


Specialized transduction designed for precise high-throughput unmarked deletions in Mycobacterium tuberculosis.

Jain P, Hsu T, Arai M, Biermann K, Thaler DS, Nguyen A, González PA, Tufariello JM, Kriakov J, Chen B, Larsen MH, Jacobs WR Jr.

MBio. 2014 Jun 3;5(3):e01245-14. doi: 10.1128/mBio.01245-14.


High-throughput sequencing enhanced phage display identifies peptides that bind mycobacteria.

Ngubane NA, Gresh L, Ioerger TR, Sacchettini JC, Zhang YJ, Rubin EJ, Pym A, Khati M.

PLoS One. 2013 Nov 12;8(11):e77844. doi: 10.1371/journal.pone.0077844. eCollection 2013.


Vaccine development for tuberculosis: current progress.

Orme IM.

Drugs. 2013 Jul;73(10):1015-24. doi: 10.1007/s40265-013-0081-8. Review.


Robust immunity to an auxotrophic Mycobacterium bovis BCG-VLP prime-boost HIV vaccine candidate in a nonhuman primate model.

Chege GK, Burgers WA, Stutz H, Meyers AE, Chapman R, Kiravu A, Bunjun R, Shephard EG, Jacobs WR Jr, Rybicki EP, Williamson AL.

J Virol. 2013 May;87(9):5151-60. doi: 10.1128/JVI.03178-12. Epub 2013 Feb 28.


Priming with a recombinant pantothenate auxotroph of Mycobacterium bovis BCG and boosting with MVA elicits HIV-1 Gag specific CD8+ T cells.

Chapman R, Shephard E, Stutz H, Douglass N, Sambandamurthy V, Garcia I, Ryffel B, Jacobs W, Williamson AL.

PLoS One. 2012;7(3):e32769. doi: 10.1371/journal.pone.0032769. Epub 2012 Mar 29.


Extended safety and efficacy studies of a live attenuated double leucine and pantothenate auxotroph of Mycobacterium tuberculosis as a vaccine candidate.

Sampson SL, Mansfield KG, Carville A, Magee DM, Quitugua T, Howerth EW, Bloom BR, Hondalus MK.

Vaccine. 2011 Jun 24;29(29-30):4839-47. doi: 10.1016/j.vaccine.2011.04.066. Epub 2011 May 5.


Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway.

Daleke MH, Cascioferro A, de Punder K, Ummels R, Abdallah AM, van der Wel N, Peters PJ, Luirink J, Manganelli R, Bitter W.

J Biol Chem. 2011 May 27;286(21):19024-34. doi: 10.1074/jbc.M110.204966. Epub 2011 Apr 6.


Genome-wide screen for Mycobacterium tuberculosis genes that regulate host immunity.

Beaulieu AM, Rath P, Imhof M, Siddall ME, Roberts J, Schnappinger D, Nathan CF.

PLoS One. 2010 Dec 10;5(12):e15120. doi: 10.1371/journal.pone.0015120.

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