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Clinical and molecular review of atypical congenital adrenal hyperplasia.

Sahakitrungruang T.

Ann Pediatr Endocrinol Metab. 2015 Mar;20(1):1-7. doi: 10.6065/apem.2015.20.1.1. Epub 2015 Mar 31. Review.


Pharmacogenomics of human P450 oxidoreductase.

Pandey AV, Sproll P.

Front Pharmacol. 2014 May 9;5:103. doi: 10.3389/fphar.2014.00103. eCollection 2014. Review.


NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells.

Gocek E, Marchwicka A, Bujko K, Marcinkowska E.

PLoS One. 2014 Mar 18;9(3):e91752. doi: 10.1371/journal.pone.0091752. eCollection 2014.


Novel associations in disorders of sex development: findings from the I-DSD Registry.

Cox K, Bryce J, Jiang J, Rodie M, Sinnott R, Alkhawari M, Arlt W, Audi L, Balsamo A, Bertelloni S, Cools M, Darendeliler F, Drop S, Ellaithi M, Guran T, Hiort O, Holterhus PM, Hughes I, Krone N, Lisa L, Morel Y, Soder O, Wieacker P, Ahmed SF.

J Clin Endocrinol Metab. 2014 Feb;99(2):E348-55. doi: 10.1210/jc.2013-2918. Epub 2013 Dec 3.


Conditional deletion of cytochrome p450 reductase in osteoprogenitor cells affects long bone and skull development in mice recapitulating antley-bixler syndrome: role of a redox enzyme in development.

Panda SP, Guntur AR, Polusani SR, Fajardo RJ, Gakunga PT, Roman LJ, Masters BS.

PLoS One. 2013 Sep 25;8(9):e75638. doi: 10.1371/journal.pone.0075638. eCollection 2013.


Measurement of Serum 17α-hydroxyprogesterone in Newborn Infants by Stable Isotope Dilution-Gas Chromatography/Mass Spectrometry.

Homma K, Hida M, Ikeda K, Yamaga N, Murata M, Hasegawa T.

Clin Pediatr Endocrinol. 2009 Jul;18(3):77-80. doi: 10.1297/cpe.18.77. Epub 2009 Aug 1.


Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem.

Klein K, Zanger UM.

Front Genet. 2013 Feb 25;4:12. doi: 10.3389/fgene.2013.00012. eCollection 2013.


Prenatal diagnosis of congenital adrenal hyperplasia caused by P450 oxidoreductase deficiency.

Reisch N, Idkowiak J, Hughes BA, Ivison HE, Abdul-Rahman OA, Hendon LG, Olney AH, Nielsen S, Harrison R, Blair EM, Dhir V, Krone N, Shackleton CH, Arlt W.

J Clin Endocrinol Metab. 2013 Mar;98(3):E528-36. doi: 10.1210/jc.2012-3449. Epub 2013 Jan 30.


Modeling of Anopheles minimus Mosquito NADPH-Cytochrome P450 Oxidoreductase (CYPOR) and Mutagenesis Analysis.

Sarapusit S, Lertkiatmongkol P, Duangkaew P, Rongnoparut P.

Int J Mol Sci. 2013 Jan 16;14(1):1788-801. doi: 10.3390/ijms14011788.


Human cytochromes P450 in health and disease.

Nebert DW, Wikvall K, Miller WL.

Philos Trans R Soc Lond B Biol Sci. 2013 Jan 6;368(1612):20120431. doi: 10.1098/rstb.2012.0431. Print 2013 Feb 19. Review.


NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicology.

Riddick DS, Ding X, Wolf CR, Porter TD, Pandey AV, Zhang QY, Gu J, Finn RD, Ronseaux S, McLaughlin LA, Henderson CJ, Zou L, Flück CE.

Drug Metab Dispos. 2013 Jan;41(1):12-23. doi: 10.1124/dmd.112.048991. Epub 2012 Oct 19.


Molecular Diagnosis of Congenital Adrenal Hyperplasia in Iran: Focusing on CYP21A2 Gene.

Rabbani B, Mahdieh N, Haghi Ashtiani MT, Akbari MT, Rabbani A.

Iran J Pediatr. 2011 Jun;21(2):139-50.


NADPH-cytochrome P450 oxidoreductase: prototypic member of the diflavin reductase family.

Iyanagi T, Xia C, Kim JJ.

Arch Biochem Biophys. 2012 Dec 1;528(1):72-89. doi: 10.1016/ Epub 2012 Sep 11. Review.


Influence of various polymorphic variants of cytochrome P450 oxidoreductase (POR) on drug metabolic activity of CYP3A4 and CYP2B6.

Chen X, Pan LQ, Naranmandura H, Zeng S, Chen SQ.

PLoS One. 2012;7(6):e38495. doi: 10.1371/journal.pone.0038495. Epub 2012 Jun 12.


Heme oxygenase isoforms differ in their subcellular trafficking during hypoxia and are differentially modulated by cytochrome P450 reductase.

Linnenbaum M, Busker M, Kraehling JR, Behrends S.

PLoS One. 2012;7(4):e35483. doi: 10.1371/journal.pone.0035483. Epub 2012 Apr 24.


Identification of six novel P450 oxidoreductase missense variants in Ashkenazi and Moroccan Jewish populations.

Tomková M, Marohnic CC, Gurwitz D, Seda O, Masters BS, Martásek P.

Pharmacogenomics. 2012 Apr;13(5):543-54. doi: 10.2217/pgs.12.21.


Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes.

D'Agostino J, Ding X, Zhang P, Jia K, Fang C, Zhu Y, Spink DC, Zhang QY.

J Biol Chem. 2012 May 18;287(21):17777-88. doi: 10.1074/jbc.M112.354274. Epub 2012 Mar 27.


A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency.

Idkowiak J, Randell T, Dhir V, Patel P, Shackleton CH, Taylor NF, Krone N, Arlt W.

J Clin Endocrinol Metab. 2012 Mar;97(3):E465-75. doi: 10.1210/jc.2011-2413. Epub 2011 Dec 14.


Genotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency.

Krone N, Reisch N, Idkowiak J, Dhir V, Ivison HE, Hughes BA, Rose IT, O'Neil DM, Vijzelaar R, Smith MJ, MacDonald F, Cole TR, Adolphs N, Barton JS, Blair EM, Braddock SR, Collins F, Cragun DL, Dattani MT, Day R, Dougan S, Feist M, Gottschalk ME, Gregory JW, Haim M, Harrison R, Olney AH, Hauffa BP, Hindmarsh PC, Hopkin RJ, Jira PE, Kempers M, Kerstens MN, Khalifa MM, Köhler B, Maiter D, Nielsen S, O'Riordan SM, Roth CL, Shane KP, Silink M, Stikkelbroeck NM, Sweeney E, Szarras-Czapnik M, Waterson JR, Williamson L, Hartmann MF, Taylor NF, Wudy SA, Malunowicz EM, Shackleton CH, Arlt W.

J Clin Endocrinol Metab. 2012 Feb;97(2):E257-67. doi: 10.1210/jc.2011-0640. Epub 2011 Dec 7.


Formation of P450 · P450 complexes and their effect on P450 function.

Reed JR, Backes WL.

Pharmacol Ther. 2012 Mar;133(3):299-310. doi: 10.1016/j.pharmthera.2011.11.009. Epub 2011 Nov 29. Review.

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