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Cited In for PubMed (Select 14704432)


Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment.

Hoffman-Luca CG, Yang CY, Lu J, Ziazadeh D, McEachern D, Debussche L, Wang S.

PLoS One. 2015 Jun 12;10(6):e0128807. doi: 10.1371/journal.pone.0128807. eCollection 2015.


Elucidation of Ligand-Dependent Modulation of Disorder-Order Transitions in the Oncoprotein MDM2.

Bueren-Calabuig JA, Michel J.

PLoS Comput Biol. 2015 Jun 5;11(6):e1004282. doi: 10.1371/journal.pcbi.1004282. eCollection 2015 Jun.


MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4.

Marcar L, Ihrig B, Hourihan J, Bray SE, Quinlan PR, Jordan LB, Thompson AM, Hupp TR, Meek DW.

PLoS One. 2015 May 22;10(5):e0127713. doi: 10.1371/journal.pone.0127713. eCollection 2015.


8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction.

Pettersson M, Bliman D, Jacobsson J, Nilsson JR, Min J, Iconaru L, Guy RK, Kriwacki RW, Andréasson J, Grøtli M.

PLoS One. 2015 May 5;10(5):e0124423. doi: 10.1371/journal.pone.0124423. eCollection 2015.


Identification of Protein-Ligand Binding Sites by the Level-Set Variational Implicit-Solvent Approach.

Guo Z, Li B, Cheng LT, Zhou S, McCammon JA, Che J.

J Chem Theory Comput. 2015 Feb 10;11(2):753-765. Epub 2015 Jan 7.


Ligand deconstruction: Why some fragment binding positions are conserved and others are not.

Kozakov D, Hall DR, Jehle S, Luo L, Ochiana SO, Jones EV, Pollastri M, Allen KN, Whitty A, Vajda S.

Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2585-94. doi: 10.1073/pnas.1501567112. Epub 2015 Apr 27.


High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation.

Sokka M, Rilla K, Miinalainen I, Pospiech H, Syväoja JE.

Nucleic Acids Res. 2015 May 26;43(10):4975-89. doi: 10.1093/nar/gkv371. Epub 2015 Apr 27.


Inhibition of MDM2 homodimerization by XIAP IRES stabilizes MDM2, influencing cancer cell survival.

Liu T, Zhang H, Xiong J, Yi S, Gu L, Zhou M.

Mol Cancer. 2015 Mar 26;14:65. doi: 10.1186/s12943-015-0334-0.


Quantification of HER family receptors in breast cancer.

Nuciforo P, Radosevic-Robin N, Ng T, Scaltriti M.

Breast Cancer Res. 2015 Apr 9;17:53. doi: 10.1186/s13058-015-0561-8.


Targeting Cullin-RING E3 ubiquitin ligases for drug discovery: structure, assembly and small-molecule modulation.

Bulatov E, Ciulli A.

Biochem J. 2015 May 1;467(3):365-86. doi: 10.1042/BJ20141450. Review.


Structure- and ligand-based virtual screening identifies new scaffolds for inhibitors of the oncoprotein MDM2.

Houston DR, Yen LH, Pettit S, Walkinshaw MD.

PLoS One. 2015 Apr 17;10(4):e0121424. doi: 10.1371/journal.pone.0121424. eCollection 2015.


Nutlin-3 down-regulates retinoblastoma protein expression and inhibits muscle cell differentiation.

Walsh EM, Niu M, Bergholz J, Jim Xiao ZX.

Biochem Biophys Res Commun. 2015 May 29;461(2):293-9. doi: 10.1016/j.bbrc.2015.04.024. Epub 2015 Apr 12.


Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival.

Gillory LA, Stewart JE, Megison ML, Waters AM, Beierle EA.

J Surg Res. 2015 Jun 15;196(2):339-49. doi: 10.1016/j.jss.2015.03.021. Epub 2015 Mar 14.


Heroin activates ATF3 and CytC via c-Jun N-terminal kinase pathways to mediate neuronal apoptosis.

Pu H, Wang X, Su L, Ma C, Zhang Y, Zhang L, Chen X, Li X, Wang H, Liu X, Zhang J.

Med Sci Monit Basic Res. 2015 Apr 7;21:53-62. doi: 10.12659/MSMBR.893827.


Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles.

Fontaine F, Overman J, François M.

Cell Regen (Lond). 2015 Mar 12;4(1):2. doi: 10.1186/s13619-015-0015-x. eCollection 2015.


New perspective on targeting the tumor suppressor p53 pathway in the tumor microenvironment to enhance the efficacy of immunotherapy.

Guo G, Cui Y.

J Immunother Cancer. 2015 Mar 24;3:9. doi: 10.1186/s40425-015-0053-5. eCollection 2015.


Regulation of the DNA damage response by ubiquitin conjugation.

Brinkmann K, Schell M, Hoppe T, Kashkar H.

Front Genet. 2015 Mar 10;6:98. doi: 10.3389/fgene.2015.00098. eCollection 2015. Review.


Expression of p53 target genes in the early phase of long-term potentiation in the rat hippocampal CA1 area.

Pustylnyak VO, Lisachev PD, Shtark MB.

Neural Plast. 2015;2015:242158. doi: 10.1155/2015/242158. Epub 2015 Feb 12.


The histone code reader SPIN1 controls RET signaling in liposarcoma.

Franz H, Greschik H, Willmann D, Ozretić L, Jilg CA, Wardelmann E, Jung M, Buettner R, Schüle R.

Oncotarget. 2015 Mar 10;6(7):4773-89.

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