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Items: 1 to 20 of 26


Deubiquitinase CYLD acts as a negative regulator for bacterium NTHi-induced inflammation by suppressing K63-linked ubiquitination of MyD88.

Lee BC, Miyata M, Lim JH, Li JD.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E165-71. doi: 10.1073/pnas.1518615113. Epub 2015 Dec 30.


The TRAF-interacting protein (TRAIP) is a novel E2F target with peak expression in mitosis.

Chapard C, Hohl D, Huber M.

Oncotarget. 2015 Aug 28;6(25):20933-45.


Tumor necrosis factor (TNF) receptor-associated factor (TRAF)-interacting protein (TRIP) negatively regulates the TRAF2 ubiquitin-dependent pathway by suppressing the TRAF2-sphingosine 1-phosphate (S1P) interaction.

Park ES, Choi S, Shin B, Yu J, Yu J, Hwang JM, Yun H, Chung YH, Choi JS, Choi Y, Rho J.

J Biol Chem. 2015 Apr 10;290(15):9660-73. doi: 10.1074/jbc.M114.609685. Epub 2015 Feb 25.


CYLD-mediated signaling and diseases.

Mathis BJ, Lai Y, Qu C, Janicki JS, Cui T.

Curr Drug Targets. 2015;16(4):284-94. Review.


TRIP/NOPO E3 ubiquitin ligase promotes ubiquitylation of DNA polymerase η.

Wallace HA, Merkle JA, Yu MC, Berg TG, Lee E, Bosco G, Lee LA.

Development. 2014 Mar;141(6):1332-41. doi: 10.1242/dev.101196. Epub 2014 Feb 19.


TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1.

Zhang M, Wang L, Zhao X, Zhao K, Meng H, Zhao W, Gao C.

J Exp Med. 2012 Sep 24;209(10):1703-11. Epub 2012 Sep 3.


CYLD inhibits melanoma growth and progression through suppression of the JNK/AP-1 and β1-integrin signaling pathways.

Ke H, Augustine CK, Gandham VD, Jin JY, Tyler DS, Akiyama SK, Hall RP, Zhang JY.

J Invest Dermatol. 2013 Jan;133(1):221-9. doi: 10.1038/jid.2012.253. Epub 2012 Jul 26.


Pathogenetic importance and therapeutic implications of NF-κB in lymphoid malignancies.

Lim KH, Yang Y, Staudt LM.

Immunol Rev. 2012 Mar;246(1):359-78. doi: 10.1111/j.1600-065X.2012.01105.x. Review.


NOPO modulates Egr-induced JNK-independent cell death in Drosophila.

Ma X, Huang J, Yang L, Yang Y, Li W, Xue L.

Cell Res. 2012 Feb;22(2):425-31. doi: 10.1038/cr.2011.135. Epub 2011 Aug 16.


Serum response factor controls CYLD expression via MAPK signaling pathway.

Liang G, Ahlqvist K, Pannem R, Posern G, Massoumi R.

PLoS One. 2011 May 5;6(5):e19613. doi: 10.1371/journal.pone.0019613.


Prioritizing candidate disease genes by network-based boosting of genome-wide association data.

Lee I, Blom UM, Wang PI, Shim JE, Marcotte EM.

Genome Res. 2011 Jul;21(7):1109-21. doi: 10.1101/gr.118992.110. Epub 2011 May 2.


CYLD inhibits tumorigenesis and metastasis by blocking JNK/AP1 signaling at multiple levels.

Miliani de Marval P, Lutfeali S, Jin JY, Leshin B, Selim MA, Zhang JY.

Cancer Prev Res (Phila). 2011 Jun;4(6):851-9. doi: 10.1158/1940-6207.CAPR-10-0360. Epub 2011 Apr 8.


MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-kappaB signaling.

Liang J, Saad Y, Lei T, Wang J, Qi D, Yang Q, Kolattukudy PE, Fu M.

J Exp Med. 2010 Dec 20;207(13):2959-73. doi: 10.1084/jem.20092641. Epub 2010 Nov 29.


Oncogenic activation of NF-kappaB.

Staudt LM.

Cold Spring Harb Perspect Biol. 2010 Jun;2(6):a000109. doi: 10.1101/cshperspect.a000109. Epub 2010 Apr 21. Review.


Classical and/or alternative NF-kappaB pathway activation in multiple myeloma.

Demchenko YN, Glebov OK, Zingone A, Keats JJ, Bergsagel PL, Kuehl WM.

Blood. 2010 Apr 29;115(17):3541-52. doi: 10.1182/blood-2009-09-243535. Epub 2010 Jan 6.


CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin.

Wickström SA, Masoumi KC, Khochbin S, Fässler R, Massoumi R.

EMBO J. 2010 Jan 6;29(1):131-44. doi: 10.1038/emboj.2009.317. Epub 2009 Nov 5.


Central role of TRAF-interacting protein in a new model of brain sexual differentiation.

Krishnan S, Intlekofer KA, Aggison LK, Petersen SL.

Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16692-7. doi: 10.1073/pnas.0906293106. Epub 2009 Sep 17.


The protein-tyrosine kinase Syk interacts with TRAF-interacting protein TRIP in breast epithelial cells.

Zhou Q, Geahlen RL.

Oncogene. 2009 Mar 12;28(10):1348-56. doi: 10.1038/onc.2008.493. Epub 2009 Jan 19.


Protein partners of deubiquitinating enzymes.

Ventii KH, Wilkinson KD.

Biochem J. 2008 Sep 1;414(2):161-75. doi: 10.1042/BJ20080798. Review.

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