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Epigenetic alterations in gastric cancer (Review).

Fu DG.

Mol Med Rep. 2015 Sep;12(3):3223-30. doi: 10.3892/mmr.2015.3816. Epub 2015 May 22. Review.


A time to kill: targeting apoptosis in cancer.

Koff JL, Ramachandiran S, Bernal-Mizrachi L.

Int J Mol Sci. 2015 Jan 28;16(2):2942-55. doi: 10.3390/ijms16022942. Review.


XAF1 directs apoptotic switch of p53 signaling through activation of HIPK2 and ZNF313.

Lee MG, Han J, Jeong SI, Her NG, Lee JH, Ha TK, Kang MJ, Ryu BK, Chi SG.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15532-7. doi: 10.1073/pnas.1411746111. Epub 2014 Oct 13.


Tumor suppressor XAF1 induces apoptosis, inhibits angiogenesis and inhibits tumor growth in hepatocellular carcinoma.

Zhu LM, Shi DM, Dai Q, Cheng XJ, Yao WY, Sun PH, Ding Y, Qiao MM, Wu YL, Jiang SH, Tu SP.

Oncotarget. 2014 Jul 30;5(14):5403-15.


Combination of gefitinib and DNA methylation inhibitor decitabine exerts synergistic anti-cancer activity in colon cancer cells.

Lou YF, Zou ZZ, Chen PJ, Huang GB, Li B, Zheng DQ, Yu XR, Luo XY.

PLoS One. 2014 May 29;9(5):e97719. doi: 10.1371/journal.pone.0097719. eCollection 2014.


DNA methylation and apoptosis resistance in cancer cells.

Hervouet E, Cheray M, Vallette FM, Cartron PF.

Cells. 2013 Jul 18;2(3):545-73. doi: 10.3390/cells2030545.


Synergistic targeting of AML stem/progenitor cells with IAP antagonist birinapant and demethylating agents.

Carter BZ, Mak PY, Mak DH, Shi Y, Qiu Y, Bogenberger JM, Mu H, Tibes R, Yao H, Coombes KR, Jacamo RO, McQueen T, Kornblau SM, Andreeff M.

J Natl Cancer Inst. 2014 Feb;106(2):djt440. doi: 10.1093/jnci/djt440.


The enigmatic roles of caspases in tumor development.

J├Ąger R, Zwacka RM.

Cancers (Basel). 2010 Nov 24;2(4):1952-79. doi: 10.3390/cancers2041952.


Circulating Methylated XAF1 DNA Indicates Poor Prognosis for Gastric Cancer.

Ling ZQ, Lv P, Lu XX, Yu JL, Han J, Ying LS, Zhu X, Zhu WY, Fang XH, Wang S, Wu YC.

PLoS One. 2013 Jun 27;8(6):e67195. doi: 10.1371/journal.pone.0067195. Print 2013.


ROS and ERK1/2-mediated caspase-9 activation increases XAF1 expression in dexamethasone-induced apoptosis of EBV-transformed B cells.

Park GB, Choi Y, Kim YS, Lee HK, Kim D, Hur DY.

Int J Oncol. 2013 Jul;43(1):29-38. doi: 10.3892/ijo.2013.1949. Epub 2013 May 20.


ZNF313 is a novel cell cycle activator with an E3 ligase activity inhibiting cellular senescence by destabilizing p21(WAF1.).

Han J, Kim YL, Lee KW, Her NG, Ha TK, Yoon S, Jeong SI, Lee JH, Kang MJ, Lee MG, Ryu BK, Baik JH, Chi SG.

Cell Death Differ. 2013 Aug;20(8):1055-67. doi: 10.1038/cdd.2013.33. Epub 2013 May 3.


XAF1 is frequently methylated in human esophageal cancer.

Chen XY, He QY, Guo MZ.

World J Gastroenterol. 2012 Jun 14;18(22):2844-9. doi: 10.3748/wjg.v18.i22.2844.


Targeting apoptosis signaling pathways for anticancer therapy.

Fulda S.

Front Oncol. 2011 Aug 27;1:23. doi: 10.3389/fonc.2011.00023. eCollection 2011.


Caspases and cancer.

Olsson M, Zhivotovsky B.

Cell Death Differ. 2011 Sep;18(9):1441-9. doi: 10.1038/cdd.2011.30. Epub 2011 Apr 1. Review.


XAF1 expression and regulatory effects of somatostatin on XAF1 in prostate cancer cells.

Xing Z, Zhou Z, Yu R, Li S, Li C, Nilsson S, Liu Z.

J Exp Clin Cancer Res. 2010 Dec 11;29:162. doi: 10.1186/1756-9966-29-162.


Helicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis.

Ding SZ, Goldberg JB, Hatakeyama M.

Future Oncol. 2010 May;6(5):851-62. doi: 10.2217/fon.10.37. Review.


Down-regulation of the pro-apoptotic XIAP associated factor-1 (XAF1) during progression of clear-cell renal cancer.

Kempkensteffen C, Fritzsche FR, Johannsen M, Weikert S, Hinz S, Dietel M, Riener MO, Moch H, Jung K, Krause H, Miller K, Kristiansen G.

BMC Cancer. 2009 Aug 8;9:276. doi: 10.1186/1471-2407-9-276.


Augmentation of effects of interferon-stimulated genes by reversal of epigenetic silencing: potential application to melanoma.

Borden EC.

Cytokine Growth Factor Rev. 2007 Oct-Dec;18(5-6):491-501. Epub 2007 Aug 6. Review.

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