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Items: 1 to 20 of 79

1.

Regulators of complement activity mediate inhibitory mechanisms through a common C3b-binding mode.

Forneris F, Wu J, Xue X, Ricklin D, Lin Z, Sfyroera G, Tzekou A, Volokhina E, Granneman JC, Hauhart R, Bertram P, Liszewski MK, Atkinson JP, Lambris JD, Gros P.

EMBO J. 2016 May 17;35(10):1133-49. doi: 10.15252/embj.201593673. Epub 2016 Mar 24.

2.

The role of ADAMTS-13 activity and complement mutational analysis in differentiating acute thrombotic microangiopathies.

Phillips EH, Westwood JP, Brocklebank V, Wong EK, Tellez JO, Marchbank KJ, McGuckin S, Gale DP, Connolly J, Goodship TH, Kavanagh D, Scully MA.

J Thromb Haemost. 2016 Jan;14(1):175-85. doi: 10.1111/jth.13189. Epub 2016 Jan 11.

3.

A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.

Challis RC, Araujo GS, Wong EK, Anderson HE, Awan A, Dorman AM, Waldron M, Wilson V, Brocklebank V, Strain L, Morgan BP, Harris CL, Marchbank KJ, Goodship TH, Kavanagh D.

J Am Soc Nephrol. 2016 Jun;27(6):1617-24. doi: 10.1681/ASN.2015010100. Epub 2015 Oct 21.

PMID:
26490391
4.

Complement regulator CD46: genetic variants and disease associations.

Liszewski MK, Atkinson JP.

Hum Genomics. 2015 Jun 10;9:7. doi: 10.1186/s40246-015-0029-z. Review.

5.

The molecular and structural bases for the association of complement C3 mutations with atypical hemolytic uremic syndrome.

Martínez-Barricarte R, Heurich M, López-Perrote A, Tortajada A, Pinto S, López-Trascasa M, Sánchez-Corral P, Morgan BP, Llorca O, Harris CL, Rodríguez de Córdoba S.

Mol Immunol. 2015 Aug;66(2):263-73. doi: 10.1016/j.molimm.2015.03.248. Epub 2015 Apr 11.

6.

Genetic analysis of membrane cofactor protein (CD46) of the complement system in women with and without preeclamptic pregnancies.

Lokki AI, Aalto-Viljakainen T, Meri S, Laivuori H; FINNPEC.

PLoS One. 2015 Feb 24;10(2):e0117840. doi: 10.1371/journal.pone.0117840. eCollection 2015. Erratum in: PLoS One. 2015;10(4):e0125449.

7.

Atypical hemolytic-uremic syndrome: a case report and literature review.

Rafiq A, Tariq H, Abbas N, Shenoy R.

Am J Case Rep. 2015 Feb 24;16:109-14. doi: 10.12659/AJCR.892907. Review.

8.

Atypical hemolytic uremic syndrome post-kidney transplantation: two case reports and review of the literature.

Alasfar S, Alachkar N.

Front Med (Lausanne). 2014 Dec 12;1:52. doi: 10.3389/fmed.2014.00052. eCollection 2014. Review.

9.

Management of hemolytic uremic syndrome.

Kavanagh D, Raman S, Sheerin NS.

F1000Prime Rep. 2014 Dec 1;6:119. doi: 10.12703/P6-119. eCollection 2014. Review.

10.

Regulation of complement and modulation of its activity in monoclonal antibody therapy of cancer.

Meyer S, Leusen JH, Boross P.

MAbs. 2014;6(5):1133-44. doi: 10.4161/mabs.29670. Epub 2014 Oct 30. Review.

11.

Atypical Hemolytic Uremic Syndrome: Differential Diagnosis from TTP/HUS and Management.

Yenerel MN.

Turk J Haematol. 2014 Sep 5;31(3):216-25. doi: 10.4274/tjh.2013.0374.

12.

New functional and structural insights from updated mutational databases for complement factor H, Factor I, membrane cofactor protein and C3.

Rodriguez E, Rallapalli PM, Osborne AJ, Perkins SJ.

Biosci Rep. 2014 Oct 22;34(5). pii: e00146. doi: 10.1042/BSR20140117.

13.

Complement mutations in diacylglycerol kinase-ε-associated atypical hemolytic uremic syndrome.

Sánchez Chinchilla D, Pinto S, Hoppe B, Adragna M, Lopez L, Justa Roldan ML, Peña A, Lopez Trascasa M, Sánchez-Corral P, Rodríguez de Córdoba S.

Clin J Am Soc Nephrol. 2014 Sep 5;9(9):1611-9. doi: 10.2215/CJN.01640214. Epub 2014 Aug 18.

14.

Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission.

Volokhina EB, Westra D, van der Velden TJ, van de Kar NC, Mollnes TE, van den Heuvel LP.

Clin Exp Immunol. 2015 Aug;181(2):306-13. doi: 10.1111/cei.12426.

PMID:
25079699
15.

Genetic variants in the complement system predisposing to age-related macular degeneration: a review.

Schramm EC, Clark SJ, Triebwasser MP, Raychaudhuri S, Seddon JM, Atkinson JP.

Mol Immunol. 2014 Oct;61(2):118-25. doi: 10.1016/j.molimm.2014.06.032. Epub 2014 Jul 15. Review.

16.

Characterization of a factor H mutation that perturbs the alternative pathway of complement in a family with membranoproliferative GN.

Wong EK, Anderson HE, Herbert AP, Challis RC, Brown P, Reis GS, Tellez JO, Strain L, Fluck N, Humphrey A, Macleod A, Richards A, Ahlert D, Santibanez-Koref M, Barlow PN, Marchbank KJ, Harris CL, Goodship TH, Kavanagh D.

J Am Soc Nephrol. 2014 Nov;25(11):2425-33. doi: 10.1681/ASN.2013070732. Epub 2014 Apr 10.

17.

Acute Progression of Adult-Onset Atypical Hemolytic-Uremic Syndrome due to CFH Mutation: A Case Report.

Posnik B, Sikorska D, Hoppe K, Schwermer K, Pawlaczyk K, Oko A.

Case Rep Nephrol. 2013;2013:739820. doi: 10.1155/2013/739820. Epub 2013 Feb 21.

18.

Update on hemolytic uremic syndrome: Diagnostic and therapeutic recommendations.

Salvadori M, Bertoni E.

World J Nephrol. 2013 Aug 6;2(3):56-76. doi: 10.5527/wjn.v2.i3.56. Review.

19.

Atypical hemolytic uremic syndrome.

Kavanagh D, Goodship TH, Richards A.

Semin Nephrol. 2013 Nov;33(6):508-30. doi: 10.1016/j.semnephrol.2013.08.003. Review.

20.

Comprehensive genetic analysis of complement and coagulation genes in atypical hemolytic uremic syndrome.

Bu F, Maga T, Meyer NC, Wang K, Thomas CP, Nester CM, Smith RJ.

J Am Soc Nephrol. 2014 Jan;25(1):55-64. doi: 10.1681/ASN.2013050453. Epub 2013 Sep 12.

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