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Results: 20

1.

Targeted chiral analysis of bioactive arachidonic Acid metabolites using liquid-chromatography-mass spectrometry.

Mesaros C, Blair IA.

Metabolites. 2012 Apr 20;2(2):337-65. doi: 10.3390/metabo2020337.

PMID:
24957514
[PubMed]
Free PMC Article
2.

The interrelationship between leukotriene B4 and leukotriene-A4-hydrolase in collagen/adjuvant-induced arthritis in rats.

Mendes MT, Silveira PF.

Biomed Res Int. 2014;2014:730421. doi: 10.1155/2014/730421. Epub 2014 Feb 20.

PMID:
24701582
[PubMed - in process]
Free PMC Article
3.

Curcumin inhibits the activation of immunoglobulin e-mediated mast cells and passive systemic anaphylaxis in mice by reducing serum eicosanoid and histamine levels.

Li X, Lu Y, Jin Y, Son JK, Lee SH, Chang HW.

Biomol Ther (Seoul). 2014 Jan;22(1):27-34. doi: 10.4062/biomolther.2013.092.

PMID:
24596618
[PubMed]
Free PMC Article
4.

Modulation of basophils' degranulation and allergy-related enzymes by monomeric and dimeric naphthoquinones.

Pinho BR, Sousa C, Valentão P, Oliveira JM, Andrade PB.

PLoS One. 2014 Feb 28;9(2):e90122. doi: 10.1371/journal.pone.0090122. eCollection 2014.

PMID:
24587235
[PubMed - in process]
Free PMC Article
5.

OXER1, a G protein-coupled oxoeicosatetraenoid receptor, mediates the survival-promoting effects of arachidonate 5-lipoxygenase in prostate cancer cells.

Sarveswaran S, Ghosh J.

Cancer Lett. 2013 Aug 9;336(1):185-95. doi: 10.1016/j.canlet.2013.04.027. Epub 2013 May 2.

PMID:
23643940
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Regulation of leukotriene and 5oxoETE synthesis and the effect of 5-lipoxygenase inhibitors: a mathematical modeling approach.

Karelina TA, Zhudenkov KV, Demin OO, Svetlichny DV, Agoram B, Fairman D, Demin OV.

BMC Syst Biol. 2012 Nov 12;6:141. doi: 10.1186/1752-0509-6-141.

PMID:
23146124
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Leukotriene B4-driven neutrophil recruitment to the skin is essential for allergic skin inflammation.

Oyoshi MK, He R, Li Y, Mondal S, Yoon J, Afshar R, Chen M, Lee DM, Luo HR, Luster AD, Cho JS, Miller LS, Larson A, Murphy GF, Geha RS.

Immunity. 2012 Oct 19;37(4):747-58. doi: 10.1016/j.immuni.2012.06.018. Epub 2012 Oct 11.

PMID:
23063331
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Structure and ligand based drug design strategies in the development of novel 5- LOX inhibitors.

Aparoy P, Reddy KK, Reddanna P.

Curr Med Chem. 2012;19(22):3763-78. Review.

PMID:
22680930
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Targeted proteomics of the eicosanoid biosynthetic pathway completes an integrated genomics-proteomics-metabolomics picture of cellular metabolism.

Sabidó E, Quehenberger O, Shen Q, Chang CY, Shah I, Armando AM, Andreyev A, Vitek O, Dennis EA, Aebersold R.

Mol Cell Proteomics. 2012 Jul;11(7):M111.014746. doi: 10.1074/mcp.M111.014746. Epub 2012 Feb 23.

PMID:
22361236
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Cyclooxygenase- and lipoxygenase-mediated DNA damage.

Speed N, Blair IA.

Cancer Metastasis Rev. 2011 Dec;30(3-4):437-47. doi: 10.1007/s10555-011-9298-8. Review.

PMID:
22009064
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

On the inhibition of 5-lipoxygenase product formation by tryptanthrin: mechanistic studies and efficacy in vivo.

Pergola C, Jazzar B, Rossi A, Northoff H, Hamburger M, Sautebin L, Werz O.

Br J Pharmacol. 2012 Feb;165(3):765-76. doi: 10.1111/j.1476-5381.2011.01605.x.

PMID:
21797843
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Effects of transient receptor potential channel blockers on pacemaker activity in interstitial cells of Cajal from mouse small intestine.

Kim BJ, Nam JH, Kim SJ.

Mol Cells. 2011 Aug;32(2):153-60. doi: 10.1007/s10059-011-1019-1. Epub 2011 May 20.

PMID:
21607648
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis.

Chen M, Lam BK, Luster AD, Zarini S, Murphy RC, Bair AM, Soberman RJ, Lee DM.

J Immunol. 2010 Nov 1;185(9):5503-11. doi: 10.4049/jimmunol.1001258. Epub 2010 Sep 27.

PMID:
20876351
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase.

Chen HC, Xie J, Zhang Z, Su LT, Yue L, Runnels LW.

PLoS One. 2010 Jun 17;5(6):e11161. doi: 10.1371/journal.pone.0011161.

PMID:
20567598
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Neuroinflammation in Alzheimer's disease: mechanisms, pathologic consequences, and potential for therapeutic manipulation.

Hensley K.

J Alzheimers Dis. 2010;21(1):1-14. doi: 10.3233/JAD-2010-1414. Review.

PMID:
20182045
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

5-Lipoxygenase-mediated endogenous DNA damage.

Jian W, Lee SH, Williams MV, Blair IA.

J Biol Chem. 2009 Jun 19;284(25):16799-807. doi: 10.1074/jbc.M109.011841. Epub 2009 Apr 23.

PMID:
19390118
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15.

Tang F, Chen Z, Ciszewski C, Setty M, Solus J, Tretiakova M, Ebert E, Han J, Lin A, Guandalini S, Groh V, Spies T, Green P, Jabri B.

J Exp Med. 2009 Mar 16;206(3):707-19. doi: 10.1084/jem.20071887. Epub 2009 Feb 23.

PMID:
19237603
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The molecular mechanism of the inhibition by licofelone of the biosynthesis of 5-lipoxygenase products.

Fischer L, Hornig M, Pergola C, Meindl N, Franke L, Tanrikulu Y, Dodt G, Schneider G, Steinhilber D, Werz O.

Br J Pharmacol. 2007 Oct;152(4):471-80. Epub 2007 Aug 20.

PMID:
17704828
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The structure of coral allene oxide synthase reveals a catalase adapted for metabolism of a fatty acid hydroperoxide.

Oldham ML, Brash AR, Newcomer ME.

Proc Natl Acad Sci U S A. 2005 Jan 11;102(2):297-302. Epub 2004 Dec 29.

PMID:
15625113
[PubMed - indexed for MEDLINE]
Free PMC Article

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