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Items: 1 to 20 of 30

1.

Anxiety-like behaviors at the end of the nocturnal period in sP rats with a "history" of unpredictable, limited access to alcohol.

Colombo G, Lobina C, Maccioni P, Carai MA, Lorrai I, Zaru A, Contini A, Mugnaini C, Corelli F, Gessa GL.

Alcohol. 2015 Nov;49(7):707-12. doi: 10.1016/j.alcohol.2015.04.010. Epub 2015 Jul 21.

PMID:
26254964
2.

GABAB receptor upregulates fragile X mental retardation protein expression in neurons.

Zhang W, Xu C, Tu H, Wang Y, Sun Q, Hu P, Hu Y, Rondard P, Liu J.

Sci Rep. 2015 May 28;5:10468. doi: 10.1038/srep10468.

3.

Discovery of a Negative Allosteric Modulator of GABAB Receptors.

Chen LH, Sun B, Zhang Y, Xu TJ, Xia ZX, Liu JF, Nan FJ.

ACS Med Chem Lett. 2014 May 27;5(7):742-7. doi: 10.1021/ml500162z. eCollection 2014 Jul 10.

4.

Evaluation of peripheral versus central effects of GABA(B) receptor activation using a novel, positive allosteric modulator of the GABA(B) receptor ADX71943, a pharmacological tool compound with a fully peripheral activity profile.

Kalinichev M, Donovan-Rodriguez T, Girard F, Riguet E, Rouillier M, Bournique B, Haddouk H, Mutel V, Poli S.

Br J Pharmacol. 2014 Nov;171(21):4941-54. doi: 10.1111/bph.12812. Epub 2014 Sep 5.

5.

Positive allosteric modulation of GABAB receptors ameliorates sensorimotor gating in rodent models.

Frau R, Bini V, Pillolla G, Malherbe P, Pardu A, Thomas AW, Devoto P, Bortolato M.

CNS Neurosci Ther. 2014 Jul;20(7):679-84. doi: 10.1111/cns.12261. Epub 2014 Apr 7.

6.

Alterations in the rate of binge ethanol consumption: implications for preclinical studies in mice.

Linsenbardt DN, Boehm SL 2nd.

Addict Biol. 2014 Sep;19(5):812-25. doi: 10.1111/adb.12052. Epub 2013 Mar 13.

7.

Discriminative stimulus effects of the GABAB receptor-positive modulator rac-BHFF: comparison with GABAB receptor agonists and drugs of abuse.

Koek W, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2013 Mar;344(3):553-60. doi: 10.1124/jpet.112.202226. Epub 2012 Dec 28.

8.

Biphasic effects of cannabinoids in anxiety responses: CB1 and GABA(B) receptors in the balance of GABAergic and glutamatergic neurotransmission.

Rey AA, Purrio M, Viveros MP, Lutz B.

Neuropsychopharmacology. 2012 Nov;37(12):2624-34. doi: 10.1038/npp.2012.123. Epub 2012 Aug 1.

9.
10.

Comparison of the effect of the GABAΒ receptor agonist, baclofen, and the positive allosteric modulator of the GABAB receptor, GS39783, on alcohol self-administration in 3 different lines of alcohol-preferring rats.

Maccioni P, Zaru A, Loi B, Lobina C, Carai MA, Gessa GL, Capra A, Mugnaini C, Pasquini S, Corelli F, Hyytiä P, Lumeng L, Colombo G.

Alcohol Clin Exp Res. 2012 Oct;36(10):1748-66. doi: 10.1111/j.1530-0277.2012.01782.x. Epub 2012 Apr 6.

11.

Effects of the GABAB receptor-positive modulators CGP7930 and rac-BHFF in baclofen- and γ-hydroxybutyrate-discriminating pigeons.

Koek W, France CP, Cheng K, Rice KC.

J Pharmacol Exp Ther. 2012 May;341(2):369-76. doi: 10.1124/jpet.111.190975. Epub 2012 Feb 7.

12.

Structure and ligand recognition of class C GPCRs.

Chun L, Zhang WH, Liu JF.

Acta Pharmacol Sin. 2012 Mar;33(3):312-23. doi: 10.1038/aps.2011.186. Epub 2012 Jan 30. Review.

13.

Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery.

Melancon BJ, Hopkins CR, Wood MR, Emmitte KA, Niswender CM, Christopoulos A, Conn PJ, Lindsley CW.

J Med Chem. 2012 Feb 23;55(4):1445-64. doi: 10.1021/jm201139r. Epub 2012 Jan 6. No abstract available.

14.

Sleep-deprivation induces changes in GABA(B) and mGlu receptor expression and has consequences for synaptic long-term depression.

Tadavarty R, Rajput PS, Wong JM, Kumar U, Sastry BR.

PLoS One. 2011;6(9):e24933. doi: 10.1371/journal.pone.0024933. Epub 2011 Sep 27.

15.

A Gut Feeling about GABA: Focus on GABA(B) Receptors.

Hyland NP, Cryan JF.

Front Pharmacol. 2010 Oct 4;1:124. doi: 10.3389/fphar.2010.00124. eCollection 2010.

16.

Allosteric modulation of the M₃ muscarinic receptor by amiodarone and N-ethylamiodarone: application of the four-ligand allosteric two-state model.

Stahl E, Elmslie G, Ellis J.

Mol Pharmacol. 2011 Sep;80(3):378-88. doi: 10.1124/mol.111.072991. Epub 2011 May 20.

17.

Reduction by the Positive Allosteric Modulator of the GABA(B) Receptor, GS39783, of Alcohol Self-Administration in Sardinian Alcohol-Preferring Rats Exposed to the "Sipper" Procedure.

Maccioni P, Flore P, Carai MA, Mugnaini C, Pasquini S, Corelli F, Gessa GL, Colombo G.

Front Psychiatry. 2010 Jul 19;1:20. doi: 10.3389/fpsyt.2010.00020. eCollection 2010.

18.

Both GABA(B) receptor activation and blockade exacerbated anhedonic aspects of nicotine withdrawal in rats.

Vlachou S, Paterson NE, Guery S, Kaupmann K, Froestl W, Banerjee D, Finn MG, Markou A.

Eur J Pharmacol. 2011 Mar 25;655(1-3):52-8. doi: 10.1016/j.ejphar.2011.01.009. Epub 2011 Jan 22.

19.

Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats.

Vlachou S, Guery S, Froestl W, Banerjee D, Benedict J, Finn MG, Markou A.

Psychopharmacology (Berl). 2011 May;215(1):117-28. doi: 10.1007/s00213-010-2119-x. Epub 2010 Dec 22.

20.

Trans-activation between 7TM domains: implication in heterodimeric GABAB receptor activation.

Monnier C, Tu H, Bourrier E, Vol C, Lamarque L, Trinquet E, Pin JP, Rondard P.

EMBO J. 2011 Jan 5;30(1):32-42. doi: 10.1038/emboj.2010.270. Epub 2010 Nov 9.

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