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A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function.

Zeng M, Shang Y, Guo T, He Q, Yung WH, Liu K, Zhang M.

Proc Natl Acad Sci U S A. 2016 May 31;113(22):E3081-90. doi: 10.1073/pnas.1523265113. Epub 2016 May 16.


Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site.

Fujiwara Y, Goda N, Tamashiro T, Narita H, Satomura K, Tenno T, Nakagawa A, Oda M, Suzuki M, Sakisaka T, Takai Y, Hiroaki H.

Protein Sci. 2015 Mar;24(3):376-85. doi: 10.1002/pro.2628. Epub 2015 Jan 13.


Whirlin and PDZ domain-containing 7 (PDZD7) proteins are both required to form the quaternary protein complex associated with Usher syndrome type 2.

Chen Q, Zou J, Shen Z, Zhang W, Yang J.

J Biol Chem. 2014 Dec 26;289(52):36070-88. doi: 10.1074/jbc.M114.610535. Epub 2014 Nov 18.


A unique PDZ domain and arrestin-like fold interaction reveals mechanistic details of endocytic recycling by SNX27-retromer.

Gallon M, Clairfeuille T, Steinberg F, Mas C, Ghai R, Sessions RB, Teasdale RD, Collins BM, Cullen PJ.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3604-13. doi: 10.1073/pnas.1410552111. Epub 2014 Aug 18.


Periaxin and AHNAK nucleoprotein 2 form intertwined homodimers through domain swapping.

Han H, Kursula P.

J Biol Chem. 2014 May 16;289(20):14121-31. doi: 10.1074/jbc.M114.554816. Epub 2014 Mar 27.


Adiponectin receptor 1 C-terminus interacts with PDZ-domain proteins such as syntrophins.

Neumeier M, Krautbauer S, Schmidhofer S, Hader Y, Eisinger K, Eggenhofer E, Froehner SC, Adams ME, Mages W, Buechler C.

Exp Mol Pathol. 2013 Oct;95(2):180-6. doi: 10.1016/j.yexmp.2013.07.002. Epub 2013 Jul 13.


Noncanonical role of the PDZ4 domain of the adaptor protein PDZK1 in the regulation of the hepatic high density lipoprotein receptor scavenger receptor class B, type I (SR-BI).

Tsukamoto K, Wales TE, Daniels K, Pal R, Sheng R, Cho W, Stafford W, Engen JR, Krieger M, Kocher O.

J Biol Chem. 2013 Jul 5;288(27):19845-60. doi: 10.1074/jbc.M113.460170. Epub 2013 May 17.


Characterization of PDZ domain-peptide interaction interface based on energetic patterns.

Li N, Hou T, Ding B, Wang W.

Proteins. 2011 Nov;79(11):3208-20. doi: 10.1002/prot.23157. Epub 2011 Sep 17. Erratum in: Proteins. 2013 Sep;81(9):1676.


Identification of specificity determining residues in peptide recognition domains using an information theoretic approach applied to large-scale binding maps.

Yip KY, Utz L, Sitwell S, Hu X, Sidhu SS, Turk BE, Gerstein M, Kim PM.

BMC Biol. 2011 Aug 11;9:53. doi: 10.1186/1741-7007-9-53.


Crystallization and preliminary diffraction analysis of the CAL PDZ domain in complex with a selective peptide inhibitor.

Amacher JF, Cushing PR, Weiner JA, Madden DR.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt 5):600-3. doi: 10.1107/S1744309111009985. Epub 2011 Apr 28.


A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding.

Lenfant N, Polanowska J, Bamps S, Omi S, Borg JP, Reboul J.

BMC Genomics. 2010 Nov 26;11:671. doi: 10.1186/1471-2164-11-671.


PDZ domains and their binding partners: structure, specificity, and modification.

Lee HJ, Zheng JJ.

Cell Commun Signal. 2010 May 28;8:8. doi: 10.1186/1478-811X-8-8.


Organelle tethering by a homotypic PDZ interaction underlies formation of the Golgi membrane network.

Sengupta D, Truschel S, Bachert C, Linstedt AD.

J Cell Biol. 2009 Jul 13;186(1):41-55. doi: 10.1083/jcb.200902110. Epub 2009 Jul 6.


The postsynaptic density proteins Homer and Shank form a polymeric network structure.

Hayashi MK, Tang C, Verpelli C, Narayanan R, Stearns MH, Xu RM, Li H, Sala C, Hayashi Y.

Cell. 2009 Apr 3;137(1):159-71. doi: 10.1016/j.cell.2009.01.050.


Structure of the second PDZ domain from human zonula occludens 2.

Chen H, Tong S, Li X, Wu J, Zhu Z, Niu L, Teng M.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Apr 1;65(Pt 4):327-30. doi: 10.1107/S1744309109002334. Epub 2009 Mar 25.


Signaling pathways of PDZ2 domain: a molecular dynamics interaction correlation analysis.

Kong Y, Karplus M.

Proteins. 2009 Jan;74(1):145-54. doi: 10.1002/prot.22139.


Structural and functional analysis of the PDZ domains of human HtrA1 and HtrA3.

Runyon ST, Zhang Y, Appleton BA, Sazinsky SL, Wu P, Pan B, Wiesmann C, Skelton NJ, Sidhu SS.

Protein Sci. 2007 Nov;16(11):2454-71.


Domain swapping within PDZ2 is responsible for dimerization of ZO proteins.

Fanning AS, Lye MF, Anderson JM, Lavie A.

J Biol Chem. 2007 Dec 28;282(52):37710-6. Epub 2007 Oct 9.


Structural and functional analysis of the ligand specificity of the HtrA2/Omi PDZ domain.

Zhang Y, Appleton BA, Wu P, Wiesmann C, Sidhu SS.

Protein Sci. 2007 Aug;16(8):1738-50.


Crystal structures of autoinhibitory PDZ domain of Tamalin: implications for metabotropic glutamate receptor trafficking regulation.

Sugi T, Oyama T, Muto T, Nakanishi S, Morikawa K, Jingami H.

EMBO J. 2007 Apr 18;26(8):2192-205. Epub 2007 Mar 29.

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