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Results: 1 to 20 of 82

Cited In for PubMed (Select 12949490)


Altered cofactor regulation with disease-associated p97/VCP mutations.

Zhang X, Gui L, Zhang X, Bulfer SL, Sanghez V, Wong DE, Lee Y, Lehmann L, Lee JS, Shih PY, Lin HJ, Iacovino M, Weihl CC, Arkin MR, Wang Y, Chou TF.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):E1705-14. doi: 10.1073/pnas.1418820112. Epub 2015 Mar 16.


The Pex1/Pex6 Complex Is a Heterohexameric AAA+ Motor with Alternating and Highly Coordinated Subunits.

Gardner BM, Chowdhury S, Lander GC, Martin A.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1375-88. doi: 10.1016/j.jmb.2015.01.019. Epub 2015 Feb 7.


Mechanistic insights into the recycling machine of the SNARE complex.

Zhao M, Wu S, Zhou Q, Vivona S, Cipriano DJ, Cheng Y, Brunger AT.

Nature. 2015 Feb 5;518(7537):61-7. doi: 10.1038/nature14148. Epub 2015 Jan 12.


Nucleocytoplasmic shuttling of valosin-containing protein (VCP/p97) regulated by its N domain and C-terminal region.

Song C, Wang Q, Song C, Lockett SJ, Colburn NH, Li CC, Wang JM, Rogers TJ.

Biochim Biophys Acta. 2015 Jan;1853(1):222-32. doi: 10.1016/j.bbamcr.2014.10.019. Epub 2014 Oct 30.


xMDFF: molecular dynamics flexible fitting of low-resolution X-ray structures.

McGreevy R, Singharoy A, Li Q, Zhang J, Xu D, Perozo E, Schulten K.

Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2344-55. doi: 10.1107/S1399004714013856. Epub 2014 Aug 29.


Deformable elastic network refinement for low-resolution macromolecular crystallography.

Schröder GF, Levitt M, Brunger AT.

Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2241-55. doi: 10.1107/S1399004714016496. Epub 2014 Aug 29.


Emerging mechanistic insights into AAA complexes regulating proteasomal degradation.

Förster F, Schuller JM, Unverdorben P, Aufderheide A.

Biomolecules. 2014 Aug 6;4(3):774-94. doi: 10.3390/biom4030774. Review.


Biochemical and cellular analysis of human variants of the DYT1 dystonia protein, TorsinA/TOR1A.

Hettich J, Ryan SD, de Souza ON, Saraiva Macedo Timmers LF, Tsai S, Atai NA, da Hora CC, Zhang X, Kothary R, Snapp E, Ericsson M, Grundmann K, Breakefield XO, Nery FC.

Hum Mutat. 2014 Sep;35(9):1101-13. doi: 10.1002/humu.22602. Epub 2014 Jul 17.


Specific inhibition of p97/VCP ATPase and kinetic analysis demonstrate interaction between D1 and D2 ATPase domains.

Chou TF, Bulfer SL, Weihl CC, Li K, Lis LG, Walters MA, Schoenen FJ, Lin HJ, Deshaies RJ, Arkin MR.

J Mol Biol. 2014 Jul 29;426(15):2886-99. doi: 10.1016/j.jmb.2014.05.022. Epub 2014 May 27.


The final moments of misfolded proteins en route to the proteasome.

Zhang T, Ye Y.

DNA Cell Biol. 2014 Aug;33(8):477-83. doi: 10.1089/dna.2014.2452. Epub 2014 May 15. Review.


Anomalous diffraction in crystallographic phase evaluation.

Hendrickson WA.

Q Rev Biophys. 2014 Feb;47(1):49-93. doi: 10.1017/S0033583514000018. Review.


Architecture and assembly of the archaeal Cdc48*20S proteasome.

Barthelme D, Chen JZ, Grabenstatter J, Baker TA, Sauer RT.

Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):E1687-94. doi: 10.1073/pnas.1404823111. Epub 2014 Apr 7.


The p97-FAF1 protein complex reveals a common mode of p97 adaptor binding.

Ewens CA, Panico S, Kloppsteck P, McKeown C, Ebong IO, Robinson C, Zhang X, Freemont PS.

J Biol Chem. 2014 Apr 25;289(17):12077-84. doi: 10.1074/jbc.M114.559591. Epub 2014 Mar 11.


Structural basis for ovarian tumor domain-containing protein 1 (OTU1) binding to p97/valosin-containing protein (VCP).

Kim SJ, Cho J, Song EJ, Kim SJ, Kim HM, Lee KE, Suh SW, Kim EE.

J Biol Chem. 2014 May 2;289(18):12264-74. doi: 10.1074/jbc.M113.523936. Epub 2014 Mar 7.


Inter-ring rotations of AAA ATPase p97 revealed by electron cryomicroscopy.

Yeung HO, Förster A, Bebeacua C, Niwa H, Ewens C, McKeown C, Zhang X, Freemont PS.

Open Biol. 2014 Mar 5;4:130142. doi: 10.1098/rsob.130142.


Altered intersubunit communication is the molecular basis for functional defects of pathogenic p97 mutants.

Tang WK, Xia D.

J Biol Chem. 2013 Dec 20;288(51):36624-35. doi: 10.1074/jbc.M113.488924. Epub 2013 Nov 6.


Exercise training reverses skeletal muscle atrophy in an experimental model of VCP disease.

Nalbandian A, Nguyen C, Katheria V, Llewellyn KJ, Badadani M, Caiozzo V, Kimonis VE.

PLoS One. 2013 Oct 9;8(10):e76187. doi: 10.1371/journal.pone.0076187. eCollection 2013.


A conserved protein with AN1 zinc finger and ubiquitin-like domains modulates Cdc48 (p97) function in the ubiquitin-proteasome pathway.

Sá-Moura B, Funakoshi M, Tomko RJ Jr, Dohmen RJ, Wu Z, Peng J, Hochstrasser M.

J Biol Chem. 2013 Nov 22;288(47):33682-96. doi: 10.1074/jbc.M113.521088. Epub 2013 Oct 11.


Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine.

Liu J, Mei Z, Li N, Qi Y, Xu Y, Shi Y, Wang F, Lei J, Gao N.

J Biol Chem. 2013 Jun 14;288(24):17597-608. doi: 10.1074/jbc.M113.458752. Epub 2013 Apr 17.


Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential.

Jiao L, Ouyang S, Liang M, Niu F, Shaw N, Wu W, Ding W, Jin C, Peng Y, Zhu Y, Zhang F, Wang T, Li C, Zuo X, Luan CH, Li D, Liu ZJ.

J Virol. 2013 Jun;87(12):6829-39. doi: 10.1128/JVI.00672-13. Epub 2013 Apr 10.

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