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Distinct encounter complexes of PAI-1 with plasminogen activators and vitronectin revealed by changes in the conformation and dynamics of the reactive center loop.

Qureshi T, Goswami S, McClintock CS, Ramsey MT, Peterson CB.

Protein Sci. 2016 Feb;25(2):499-510. doi: 10.1002/pro.2841. Epub 2015 Dec 2.


Autotaxin, a lysophospholipase D with pleomorphic effects in oncogenesis and cancer progression.

Federico L, Jeong KJ, Vellano CP, Mills GB.

J Lipid Res. 2016 Jan;57(1):25-35. doi: 10.1194/jlr.R060020. Epub 2015 May 14.


Effect of Puumala hantavirus infection on human umbilical vein endothelial cell hemostatic function: platelet interactions, increased tissue factor expression and fibrinolysis regulator release.

Goeijenbier M, Meijers JC, Anfasa F, Roose JM, van de Weg CA, Bakhtiari K, Henttonen H, Vaheri A, Osterhaus AD, van Gorp EC, Martina BE.

Front Microbiol. 2015 Mar 24;6:220. doi: 10.3389/fmicb.2015.00220. eCollection 2015.


Identification and therapeutic potential of a vitronectin binding region of meningococcal msf.

Hill DJ, Griffiths NJ, Borodina E, Andreae CA, Sessions RB, Virji M.

PLoS One. 2015 Mar 31;10(3):e0124133. doi: 10.1371/journal.pone.0124133. eCollection 2015.


Abrogation of plasminogen activator inhibitor-1-vitronectin interaction ameliorates acute kidney injury in murine endotoxemia.

Gupta KK, Donahue DL, Sandoval-Cooper MJ, Castellino FJ, Ploplis VA.

PLoS One. 2015 Mar 23;10(3):e0120728. doi: 10.1371/journal.pone.0120728. eCollection 2015.


Provisional Matrix Deposition in Hemostasis and Venous Insufficiency: Tissue Preconditioning for Nonhealing Venous Ulcers.

Parker TJ, Broadbent JA, McGovern JA, Broszczak DA, Parker CN, Upton Z.

Adv Wound Care (New Rochelle). 2015 Mar 1;4(3):174-191.


Serpin latency transition at atomic resolution.

Cazzolli G, Wang F, a Beccara S, Gershenson A, Faccioli P, Wintrode PL.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15414-9. doi: 10.1073/pnas.1407528111. Epub 2014 Oct 13.


Computational survey of peptides derived from disulphide-bonded protein loops that may serve as mediators of protein-protein interactions.

Duffy FJ, Devocelle M, Croucher DR, Shields DC.

BMC Bioinformatics. 2014 Sep 17;15:305. doi: 10.1186/1471-2105-15-305.


Myofibroblasts and the extracellular matrix network in post-myocardial infarction cardiac remodeling.

Ma Y, de Castro Brás LE, Toba H, Iyer RP, Hall ME, Winniford MD, Lange RA, Tyagi SC, Lindsey ML.

Pflugers Arch. 2014 Jun;466(6):1113-27. doi: 10.1007/s00424-014-1463-9. Epub 2014 Feb 13. Review.


Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM).

Xu X, Cai Y, Wei Y, Donate F, Juarez J, Parry G, Chen L, Meehan EJ, Ahn RW, Ugolkov A, Dubrovskyi O, O'Halloran TV, Huang M, Mazar AP.

PLoS One. 2014 Jan 21;9(1):e85349. doi: 10.1371/journal.pone.0085349. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99911.


Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex.

Florova G, Karandashova S, Declerck PJ, Idell S, Komissarov AA.

Biochemistry. 2013 Jul 9;52(27):4697-709. doi: 10.1021/bi400470s. Epub 2013 Jun 25.


Vitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages.

Bae HB, Tadie JM, Jiang S, Park DW, Bell CP, Thompson LC, Peterson CB, Thannickal VJ, Abraham E, Zmijewski JW.

J Immunol. 2013 Mar 1;190(5):2273-81. doi: 10.4049/jimmunol.1200625. Epub 2013 Jan 23.


Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation.

Fjellström O, Deinum J, Sjögren T, Johansson C, Geschwindner S, Nerme V, Legnehed A, McPheat J, Olsson K, Bodin C, Paunovic A, Gustafsson D.

J Biol Chem. 2013 Jan 11;288(2):873-85. doi: 10.1074/jbc.M112.371732. Epub 2012 Nov 15.


Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.

Kato K, Nishimasu H, Okudaira S, Mihara E, Ishitani R, Takagi J, Aoki J, Nureki O.

Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16876-81. doi: 10.1073/pnas.1208017109. Epub 2012 Oct 1.


Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity.

Jeon H, Kim JH, Kim JH, Lee WH, Lee MS, Suk K.

J Neuroinflammation. 2012 Jun 29;9:149. doi: 10.1186/1742-2094-9-149.


Effects of extracellular DNA on plasminogen activation and fibrinolysis.

Komissarov AA, Florova G, Idell S.

J Biol Chem. 2011 Dec 9;286(49):41949-62. doi: 10.1074/jbc.M111.301218. Epub 2011 Oct 5.


Crystal structure of plasminogen activator inhibitor-1 in an active conformation with normal thermodynamic stability.

Jensen JK, Thompson LC, Bucci JC, Nissen P, Gettins PG, Peterson CB, Andreasen PA, Morth JP.

J Biol Chem. 2011 Aug 26;286(34):29709-17. doi: 10.1074/jbc.M111.236554. Epub 2011 Jun 21.


Metals affect the structure and activity of human plasminogen activator inhibitor-1. I. Modulation of stability and protease inhibition.

Thompson LC, Goswami S, Ginsberg DS, Day DE, Verhamme IM, Peterson CB.

Protein Sci. 2011 Feb;20(2):353-65. doi: 10.1002/pro.568.

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