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Targeting TGF-β1 inhibits invasion of anaplastic thyroid carcinoma cell through SMAD2-dependent S100A4-MMP-2/9 signalling.

Zhang K, Liu X, Hao F, Dong A, Chen D.

Am J Transl Res. 2016 May 15;8(5):2196-209. eCollection 2016.


The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer Metastasis.

Lebrun JJ.

ISRN Mol Biol. 2012 Dec 24;2012:381428. doi: 10.5402/2012/381428. eCollection 2012. Review.


Chordin-Like 1 Suppresses Bone Morphogenetic Protein 4-Induced Breast Cancer Cell Migration and Invasion.

Cyr-Depauw C, Northey JJ, Tabariès S, Annis MG, Dong Z, Cory S, Hallett M, Rennhack JP, Andrechek ER, Siegel PM.

Mol Cell Biol. 2016 May 2;36(10):1509-25. doi: 10.1128/MCB.00600-15. Print 2016 May 15.


MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3.

Wang C, Liu P, Wu H, Cui P, Li Y, Liu Y, Liu Z, Gou S.

Oncotarget. 2016 Mar 22;7(12):14912-24. doi: 10.18632/oncotarget.7482.


BMP signaling in mesenchymal stem cell differentiation and bone formation.

Beederman M, Lamplot JD, Nan G, Wang J, Liu X, Yin L, Li R, Shui W, Zhang H, Kim SH, Zhang W, Zhang J, Kong Y, Denduluri S, Rogers MR, Pratt A, Haydon RC, Luu HH, Angeles J, Shi LL, He TC.

J Biomed Sci Eng. 2013 Aug;6(8A):32-52.


LKB1/AMPK inhibits TGF-β1 production and the TGF-β signaling pathway in breast cancer cells.

Li NS, Zou JR, Lin H, Ke R, He XL, Xiao L, Huang D, Luo L, Lv N, Luo Z.

Tumour Biol. 2016 Jun;37(6):8249-58. doi: 10.1007/s13277-015-4639-9. Epub 2015 Dec 30.


TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and Metastasis.

Papageorgis P.

J Oncol. 2015;2015:587193. doi: 10.1155/2015/587193. Epub 2015 Mar 25. Review.


Identifying and targeting tumor-initiating cells in the treatment of breast cancer.

Wei W, Lewis MT.

Endocr Relat Cancer. 2015 Jun;22(3):R135-55. doi: 10.1530/ERC-14-0447. Epub 2015 Apr 15. Review.


Role of TGFβ in regulation of the tumor microenvironment and drug delivery (review).

Papageorgis P, Stylianopoulos T.

Int J Oncol. 2015 Mar;46(3):933-43. doi: 10.3892/ijo.2015.2816. Epub 2015 Jan 7. Review.


HOXB7 promotes malignant progression by activating the TGFβ signaling pathway.

Liu S, Jin K, Hui Y, Fu J, Jie C, Feng S, Reisman D, Wang Q, Fan D, Sukumar S, Chen H.

Cancer Res. 2015 Feb 15;75(4):709-19. doi: 10.1158/0008-5472.CAN-14-3100. Epub 2014 Dec 26.


Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis.

Novitskiy SV, Forrester E, Pickup MW, Gorska AE, Chytil A, Aakre M, Polosukhina D, Owens P, Yusupova DR, Zhao Z, Ye F, Shyr Y, Moses HL.

Breast Cancer Res. 2014 Oct 4;16(5):425. doi: 10.1186/s13058-014-0425-7.


A phase I dose-escalation study to a predefined dose of a transforming growth factor-β1 monoclonal antibody (TβM1) in patients with metastatic cancer.

Cohn A, Lahn MM, Williams KE, Cleverly AL, Pitou C, Kadam SK, Farmen MW, Desaiah D, Raju R, Conkling P, Richards D.

Int J Oncol. 2014 Dec;45(6):2221-31. doi: 10.3892/ijo.2014.2679. Epub 2014 Sep 26.


TGFBR1 and cancer susceptibility.

Pasche B, Pennison MJ, Jimenez H, Wang M.

Trans Am Clin Climatol Assoc. 2014;125:300-12. Review.


An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancer.

Sato M, Kadota M, Tang B, Yang HH, Yang YA, Shan M, Weng J, Welsh MA, Flanders KC, Nagano Y, Michalowski AM, Clifford RJ, Lee MP, Wakefield LM.

Breast Cancer Res. 2014 Jun 2;16(3):R57. doi: 10.1186/bcr3668.


Context-dependent function of the deubiquitinating enzyme USP9X in pancreatic ductal adenocarcinoma.

Cox JL, Wilder PJ, Wuebben EL, Ouellette MM, Hollingsworth MA, Rizzino A.

Cancer Biol Ther. 2014 Aug;15(8):1042-52. doi: 10.4161/cbt.29182. Epub 2014 May 19. Erratum in: Cancer Biol Ther. 2016;17(3):336.


When Good Turns Bad: Regulation of Invasion and Metastasis by ErbB2 Receptor Tyrosine Kinase.

Brix DM, Clemmensen KK, Kallunki T.

Cells. 2014 Jan 27;3(1):53-78. doi: 10.3390/cells3010053.


Divergent signaling pathways cooperatively regulate TGFβ induction of cysteine-rich protein 2 in vascular smooth muscle cells.

Wu ML, Chen CH, Lin YT, Jheng YJ, Ho YC, Yang LT, Chen L, Layne MD, Yet SF.

Cell Commun Signal. 2014 Mar 28;12:22. doi: 10.1186/1478-811X-12-22.


Autocrine signaling via release of ATP and activation of P2X7 receptor influences motile activity of human lung cancer cells.

Takai E, Tsukimoto M, Harada H, Kojima S.

Purinergic Signal. 2014 Sep;10(3):487-97. doi: 10.1007/s11302-014-9411-x. Epub 2014 Mar 14.


Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis.

Daehn I, Casalena G, Zhang T, Shi S, Fenninger F, Barasch N, Yu L, D'Agati V, Schlondorff D, Kriz W, Haraldsson B, Bottinger EP.

J Clin Invest. 2014 Apr;124(4):1608-21. doi: 10.1172/JCI71195. Epub 2014 Mar 3.


Role of TGF-β in breast cancer bone metastases.

Chiechi A, Waning DL, Stayrook KR, Buijs JT, Guise TA, Mohammad KS.

Adv Biosci Biotechnol. 2013 Oct 1;4(10C):15-30.

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