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Items: 1 to 20 of 61


Early Intervention for Psychosis with N-Methyl-D-Aspartate Receptor Modulators.

Dong C, Hashimoto K.

Clin Psychopharmacol Neurosci. 2015 Dec 31;13(3):328-9. doi: 10.9758/cpn.2015.13.3.328. No abstract available.


Identification of pLG72-Induced Oxidative Stress Using Systemic Approaches.

Wang M, Chen HJ, Zhang J, Li W, Xie X, Chang HT.

Biomed Res Int. 2015;2015:429253. doi: 10.1155/2015/429253. Epub 2015 Oct 11.


Functional alterations of astrocytes in mental disorders: pharmacological significance as a drug target.

Koyama Y.

Front Cell Neurosci. 2015 Jul 6;9:261. doi: 10.3389/fncel.2015.00261. eCollection 2015. Review.


Adaptive evolution and elucidating the potential inhibitor against schizophrenia to target DAOA (G72) isoforms.

Sehgal SA, Mannan S, Kanwal S, Naveed I, Mir A.

Drug Des Devel Ther. 2015 Jul 3;9:3471-80. doi: 10.2147/DDDT.S63946. eCollection 2015.


Enantioselective inhibition of d-serine transport by (S)-ketamine.

Singh NS, Bernier M, Camandola S, Khadeer MA, Moaddel R, Mattson MP, Wainer IW.

Br J Pharmacol. 2015 Jul 3. doi: 10.1111/bph.13239. [Epub ahead of print]


A role for D-aspartate oxidase in schizophrenia and in schizophrenia-related symptoms induced by phencyclidine in mice.

Errico F, D'Argenio V, Sforazzini F, Iasevoli F, Squillace M, Guerri G, Napolitano F, Angrisano T, Di Maio A, Keller S, Vitucci D, Galbusera A, Chiariotti L, Bertolino A, de Bartolomeis A, Salvatore F, Gozzi A, Usiello A.

Transl Psychiatry. 2015 Feb 17;5:e512. doi: 10.1038/tp.2015.2.


In vivo assessment of neurotransmitters and modulators with magnetic resonance spectroscopy: application to schizophrenia.

Wijtenburg SA, Yang S, Fischer BA, Rowland LM.

Neurosci Biobehav Rev. 2015 Apr;51:276-95. doi: 10.1016/j.neubiorev.2015.01.007. Epub 2015 Jan 19. Review.


Subchronic pharmacological and chronic genetic NMDA receptor hypofunction differentially regulate the Akt signaling pathway and Arc expression in juvenile and adult mice.

Takagi S, Balu DT, Coyle JT.

Schizophr Res. 2015 Mar;162(1-3):216-21. doi: 10.1016/j.schres.2014.12.034. Epub 2015 Jan 12.


Free D-aspartate regulates neuronal dendritic morphology, synaptic plasticity, gray matter volume and brain activity in mammals.

Errico F, Nisticò R, Di Giorgio A, Squillace M, Vitucci D, Galbusera A, Piccinin S, Mango D, Fazio L, Middei S, Trizio S, Mercuri NB, Teule MA, Centonze D, Gozzi A, Blasi G, Bertolino A, Usiello A.

Transl Psychiatry. 2014 Jul 29;4:e417. doi: 10.1038/tp.2014.59.


Quantitative analyses of schizophrenia-associated metabolites in serum: serum D-lactate levels are negatively correlated with gamma-glutamylcysteine in medicated schizophrenia patients.

Fukushima T, Iizuka H, Yokota A, Suzuki T, Ohno C, Kono Y, Nishikiori M, Seki A, Ichiba H, Watanabe Y, Hongo S, Utsunomiya M, Nakatani M, Sadamoto K, Yoshio T.

PLoS One. 2014 Jul 8;9(7):e101652. doi: 10.1371/journal.pone.0101652. eCollection 2014.


D-amino acid oxidase is expressed in the ventral tegmental area and modulates cortical dopamine.

Betts JF, Schweimer JV, Burnham KE, Burnet PW, Sharp T, Harrison PJ.

Front Synaptic Neurosci. 2014 May 2;6:11. doi: 10.3389/fnsyn.2014.00011. eCollection 2014.


Overdose of D-serine Induces Movement Disorder and Neuromuscular Changes of Zebrafish Larvae.

Chen XG, Wang YH, Wen CC, Chen YH.

J Toxicol Pathol. 2014 Apr;27(1):19-24. doi: 10.1293/tox.2013-0032. Epub 2014 Apr 30.


A snapshot of plasma metabolites in first-episode schizophrenia: a capillary electrophoresis time-of-flight mass spectrometry study.

Koike S, Bundo M, Iwamoto K, Suga M, Kuwabara H, Ohashi Y, Shinoda K, Takano Y, Iwashiro N, Satomura Y, Nagai T, Natsubori T, Tada M, Yamasue H, Kasai K.

Transl Psychiatry. 2014 Apr 8;4:e379. doi: 10.1038/tp.2014.19.


Ischemic acute kidney injury perturbs homeostasis of serine enantiomers in the body fluid in mice: early detection of renal dysfunction using the ratio of serine enantiomers.

Sasabe J, Suzuki M, Miyoshi Y, Tojo Y, Okamura C, Ito S, Konno R, Mita M, Hamase K, Aiso S.

PLoS One. 2014 Jan 29;9(1):e86504. doi: 10.1371/journal.pone.0086504. eCollection 2014.


The C-terminal region of G72 increases D-amino acid oxidase activity.

Chang SL, Hsieh CH, Chen YJ, Wang CM, Shih CS, Huang PW, Mir A, Lane HY, Tsai GE, Chang HT.

Int J Mol Sci. 2013 Dec 20;15(1):29-43. doi: 10.3390/ijms15010029.


Development and validation of a sensitive LC-MS/MS method for the determination of D-serine in human plasma.

Xie Y, Alexander GM, Schwartzman RJ, N Singh, Torjman MC, Goldberg ME, Wainer IW, Moaddel R.

J Pharm Biomed Anal. 2014 Feb;89:1-5. doi: 10.1016/j.jpba.2013.10.028. Epub 2013 Oct 30.


Lysine metabolism in mammalian brain: an update on the importance of recent discoveries.

Hallen A, Jamie JF, Cooper AJ.

Amino Acids. 2013 Dec;45(6):1249-72. doi: 10.1007/s00726-013-1590-1. Epub 2013 Sep 17. Review.


Neonatal disruption of serine racemase causes schizophrenia-like behavioral abnormalities in adulthood: clinical rescue by d-serine.

Hagiwara H, Iyo M, Hashimoto K.

PLoS One. 2013 Apr 22;8(4):e62438. doi: 10.1371/journal.pone.0062438. Print 2013.


D-serine as a gliotransmitter and its roles in brain development and disease.

Van Horn MR, Sild M, Ruthazer ES.

Front Cell Neurosci. 2013 Apr 23;7:39. doi: 10.3389/fncel.2013.00039. eCollection 2013.


In vivo D-serine hetero-exchange through alanine-serine-cysteine (ASC) transporters detected by microelectrode biosensors.

Maucler C, Pernot P, Vasylieva N, Pollegioni L, Marinesco S.

ACS Chem Neurosci. 2013 May 15;4(5):772-81. doi: 10.1021/cn4000549. Epub 2013 Apr 12.

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