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Results: 1 to 20 of 83

1.

Deficiency of p110δ Isoform of the Phosphoinositide 3 Kinase Leads to Enhanced Resistance to Leishmania donovani.

Khadem F, Mou Z, Liu D, Varikuti S, Satoskar A, Uzonna JE.

PLoS Negl Trop Dis. 2014 Jun 19;8(6):e2951. doi: 10.1371/journal.pntd.0002951. eCollection 2014 Jun.

PMID:
24945303
[PubMed - in process]
Free PMC Article
2.

Liver Sinusoidal Endothelial Cell-Mediated CD8 T Cell Priming Depends on Co-Inhibitory Signal Integration over Time.

Kaczmarek J, Homsi Y, van Üüm J, Metzger C, Knolle PA, Kolanus W, Lang T, Diehl L.

PLoS One. 2014 Jun 12;9(6):e99574. doi: 10.1371/journal.pone.0099574. eCollection 2014.

PMID:
24924593
[PubMed - in process]
Free PMC Article
3.

Knockout mouse models of insulin signaling: Relevance past and future.

Bunner AE, Chandrasekera PC, Barnard ND.

World J Diabetes. 2014 Apr 15;5(2):146-59. doi: 10.4239/wjd.v5.i2.146. Review.

PMID:
24748928
[PubMed]
Free PMC Article
4.

Administration of dexamethasone protects mice against ischemia/reperfusion induced renal injury by suppressing PI3K/AKT signaling.

Zhang J, Yao Y, Xiao F, Lan X, Yu C, Zhang Y, Jiang C, Yang J, Pei G, Li Y, Rong S, Hu S, Li J, Xu G.

Int J Clin Exp Pathol. 2013 Oct 15;6(11):2366-75. eCollection 2013.

PMID:
24228098
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Co-Receptor CD8-Mediated Modulation of T-Cell Receptor Functional Sensitivity and Epitope Recognition Degeneracy.

Szomolay B, Williams T, Wooldridge L, van den Berg HA.

Front Immunol. 2013 Oct 21;4:329. doi: 10.3389/fimmu.2013.00329. Review.

PMID:
24151493
[PubMed]
Free PMC Article
6.

Role of inositol poly-phosphatases and their targets in T cell biology.

Srivastava N, Sudan R, Kerr WG.

Front Immunol. 2013 Sep 23;4:288. doi: 10.3389/fimmu.2013.00288. Review.

PMID:
24069021
[PubMed]
Free PMC Article
7.

Transcriptional profiling of mRNAs and microRNAs in human bone marrow precursor B cells identifies subset- and age-specific variations.

Jensen K, Brusletto BS, Aass HC, Olstad OK, Kierulf P, Gautvik KM.

PLoS One. 2013 Jul 30;8(7):e70721. doi: 10.1371/journal.pone.0070721. Print 2013.

PMID:
23936243
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Artemether combined with shRNA interference of vascular cell adhesion molecule-1 significantly inhibited the malignant biological behavior of human glioma cells.

Wang YB, Hu Y, Li Z, Wang P, Xue YX, Yao YL, Yu B, Liu YH.

PLoS One. 2013 Apr 11;8(4):e60834. doi: 10.1371/journal.pone.0060834. Print 2013.

PMID:
23593320
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development.

Venigalla RK, McGuire VA, Clarke R, Patterson-Kane JC, Najafov A, Toth R, McCarthy PC, Simeons F, Stojanovski L, Arthur JS.

EMBO J. 2013 Apr 3;32(7):1008-22. doi: 10.1038/emboj.2013.40. Epub 2013 Mar 5.

PMID:
23463102
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Role of PI3K/Akt signaling in memory CD8 T cell differentiation.

Kim EH, Suresh M.

Front Immunol. 2013 Feb 1;4:20. doi: 10.3389/fimmu.2013.00020. eCollection 2013.

PMID:
23378844
[PubMed]
Free PMC Article
11.

P110α-mediated constitutive PI3K signaling limits the efficacy of p110δ-selective inhibition in mantle cell lymphoma, particularly with multiple relapse.

Iyengar S, Clear A, Bödör C, Maharaj L, Lee A, Calaminici M, Matthews J, Iqbal S, Auer R, Gribben J, Joel S.

Blood. 2013 Mar 21;121(12):2274-84. doi: 10.1182/blood-2012-10-460832. Epub 2013 Jan 22.

PMID:
23341541
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation.

Yasui T, Sakakibara-Yada K, Nishimura T, Morita K, Tada S, Mosialos G, Kieff E, Kikutani H.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):21022-7. doi: 10.1073/pnas.1218925110. Epub 2012 Dec 5.

PMID:
23223530
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

All PI3Kinase signaling is not mTOR: dissecting mTOR-dependent and independent signaling pathways in T cells.

Gamper CJ, Powell JD.

Front Immunol. 2012 Oct 9;3:312. doi: 10.3389/fimmu.2012.00312. eCollection 2012.

PMID:
23087689
[PubMed]
Free PMC Article
14.
15.

XB130 mediates cancer cell proliferation and survival through multiple signaling events downstream of Akt.

Shiozaki A, Shen-Tu G, Bai X, Iitaka D, De Falco V, Santoro M, Keshavjee S, Liu M.

PLoS One. 2012;7(8):e43646. doi: 10.1371/journal.pone.0043646. Epub 2012 Aug 23.

PMID:
22928011
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions.

Pauls SD, Lafarge ST, Landego I, Zhang T, Marshall AJ.

Front Immunol. 2012 Aug 9;3:224. doi: 10.3389/fimmu.2012.00224. eCollection 2012.

PMID:
22908014
[PubMed]
Free PMC Article
17.

Regulation of glucose metabolism in T cells: new insight into the role of Phosphoinositide 3-kinases.

Finlay DK.

Front Immunol. 2012 Aug 7;3:247. doi: 10.3389/fimmu.2012.00247. eCollection 2012.

PMID:
22891069
[PubMed]
Free PMC Article
18.

Molecular pathways: targeting phosphoinositide 3-kinase p110-delta in chronic lymphocytic leukemia.

Herman SE, Johnson AJ.

Clin Cancer Res. 2012 Aug 1;18(15):4013-8. doi: 10.1158/1078-0432.CCR-11-1402. Epub 2012 Jun 18. Review.

PMID:
22711705
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inhibition of T-cell activation by PIK3IP1.

DeFrances MC, Debelius DR, Cheng J, Kane LP.

Eur J Immunol. 2012 Oct;42(10):2754-9. doi: 10.1002/eji.201141653. Epub 2012 Jul 19.

PMID:
22706993
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Functional characterization of an isoform-selective inhibitor of PI3K-p110β as a potential anticancer agent.

Ni J, Liu Q, Xie S, Carlson C, Von T, Vogel K, Riddle S, Benes C, Eck M, Roberts T, Gray N, Zhao J.

Cancer Discov. 2012 May;2(5):425-33. doi: 10.1158/2159-8290.CD-12-0003. Epub 2012 Apr 12.

PMID:
22588880
[PubMed - indexed for MEDLINE]
Free PMC Article

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