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Items: 1 to 20 of 51


The effect of environmental chemicals on the tumor microenvironment.

Casey SC, Vaccari M, Al-Mulla F, Al-Temaimi R, Amedei A, Barcellos-Hoff MH, Brown DG, Chapellier M, Christopher J, Curran CS, Forte S, Hamid RA, Heneberg P, Koch DC, Krishnakumar PK, Laconi E, Maguer-Satta V, Marongiu F, Memeo L, Mondello C, Raju J, Roman J, Roy R, Ryan EP, Ryeom S, Salem HK, Scovassi AI, Singh N, Soucek L, Vermeulen L, Whitfield JR, Woodrick J, Colacci A, Bisson WH, Felsher DW.

Carcinogenesis. 2015 Jun;36 Suppl 1:S160-83. doi: 10.1093/carcin/bgv035. Review.


Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells.

McLean LS, Watkins CN, Campbell P, Zylstra D, Rowland L, Amis LH, Scott L, Babb CE, Livingston WJ, Darwanto A, Davis WL Jr, Senthil M, Sowers LC, Brantley E.

Chem Res Toxicol. 2015 May 18;28(5):855-71. doi: 10.1021/tx500485v. Epub 2015 Apr 1.


Insulin/Insulin-like growth factors in cancer: new roles for the aryl hydrocarbon receptor, tumor resistance mechanisms, and new blocking strategies.

Salisbury TB, Tomblin JK.

Front Endocrinol (Lausanne). 2015 Feb 2;6:12. doi: 10.3389/fendo.2015.00012. eCollection 2015. Review.


Aryl hydrocarbon receptor ligands in cancer: friend and foe.

Murray IA, Patterson AD, Perdew GH.

Nat Rev Cancer. 2014 Dec;14(12):801-14. Review.


Indole-3-carbinol and its N-alkoxy derivatives preferentially target ERα-positive breast cancer cells.

Caruso JA, Campana R, Wei C, Su CH, Hanks AM, Bornmann WG, Keyomarsi K.

Cell Cycle. 2014;13(16):2587-99. doi: 10.4161/15384101.2015.942210.


2-(4-Hydroxy-3-methoxyphenyl)-benzothiazole suppresses tumor progression and metastatic potential of breast cancer cells by inducing ubiquitin ligase CHIP.

Hiyoshi H, Goto N, Tsuchiya M, Iida K, Nakajima Y, Hirata N, Kanda Y, Nagasawa K, Yanagisawa J.

Sci Rep. 2014 Nov 18;4:7095. doi: 10.1038/srep07095.


Competitive molecular docking approach for predicting estrogen receptor subtype α agonists and antagonists.

Ng HW, Zhang W, Shu M, Luo H, Ge W, Perkins R, Tong W, Hong H.

BMC Bioinformatics. 2014;15 Suppl 11:S4. doi: 10.1186/1471-2105-15-S11-S4. Epub 2014 Oct 21.


Defining molecular sensors to assess long-term effects of pesticides on carcinogenesis.

L'Héritier F, Marques M, Fauteux M, Gaudreau L.

Int J Mol Sci. 2014 Sep 25;15(9):17148-61. doi: 10.3390/ijms150917148. Review.


Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae).

Ateba SB, Njamen D, Medjakovic S, Zehl M, Kaehlig H, Jungbauer A, Krenn L.

BMC Complement Altern Med. 2014 Aug 9;14:294. doi: 10.1186/1472-6882-14-294.


The Aryl Hydrocarbon Receptor: A Target for Breast Cancer Therapy.

Powell JB, Goode GD, Eltom SE.

J Cancer Ther. 2013 Sep;4(7):1177-1186.


Coactivator recruitment of AhR/ARNT1.

Endler A, Chen L, Shibasaki F.

Int J Mol Sci. 2014 Jun 19;15(6):11100-10. doi: 10.3390/ijms150611100. Review.


Homology modeling, molecular docking, and molecular dynamics simulations elucidated α-fetoprotein binding modes.

Shen J, Zhang W, Fang H, Perkins R, Tong W, Hong H.

BMC Bioinformatics. 2013;14 Suppl 14:S6. doi: 10.1186/1471-2105-14-S14-S6. Epub 2013 Oct 9.


Beta-naphthoflavone (DB06732) mediates estrogen receptor-positive breast cancer cell cycle arrest through AhR-dependent regulation of PI3K/AKT and MAPK/ERK signaling.

Wang C, Xu CX, Bu Y, Bottum KM, Tischkau SA.

Carcinogenesis. 2014 Mar;35(3):703-13. doi: 10.1093/carcin/bgt356. Epub 2013 Oct 26.


Multi-nutrient supplement improves hormone ratio associated with cancer risk.

Bazzan AJ, Zabrecky GP, Newberg AB.

J Transl Med. 2013 Oct 8;11:252. doi: 10.1186/1479-5876-11-252.


Role of the aryl hydrocarbon receptor in carcinogenesis and potential as a drug target.

Safe S, Lee SO, Jin UH.

Toxicol Sci. 2013 Sep;135(1):1-16. doi: 10.1093/toxsci/kft128. Epub 2013 Jun 14. Review.


Assessment and molecular actions of endocrine-disrupting chemicals that interfere with estrogen receptor pathways.

Kerdivel G, Habauzit D, Pakdel F.

Int J Endocrinol. 2013;2013:501851. doi: 10.1155/2013/501851. Epub 2013 May 2.


Mechanisms underlying the varied mammary carcinogenicity of the environmental pollutant 6-nitrochrysene and its metabolites (-)-[R,R]- and (+)-[S,S]-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene in the rat.

Sun YW, Guttenplan JB, Cooper T, Krzeminski J, Aliaga C, Boyiri T, Kosinska W, Zhao ZL, Chen KM, Berg A, Amin S, El-Bayoumy K.

Chem Res Toxicol. 2013 Apr 15;26(4):547-54. doi: 10.1021/tx300478z. Epub 2013 Mar 28.


Genetic polymorphisms in the aryl hydrocarbon receptor signaling pathway as potential risk factors of menopausal hot flashes.

Ziv-Gal A, Gallicchio L, Miller SR, Zacur HA, Flaws JA.

Am J Obstet Gynecol. 2012 Sep;207(3):202.e9-202.e18. doi: 10.1016/j.ajog.2012.05.019. Epub 2012 Jun 1.


Expression of the aryl hydrocarbon receptor is not required for the proliferation, migration, invasion, or estrogen-dependent tumorigenesis of MCF-7 breast cancer cells.

Spink BC, Bennett JA, Lostritto N, Cole JR, Spink DC.

Mol Carcinog. 2013 Jul;52(7):544-54. doi: 10.1002/mc.21889. Epub 2012 Mar 2.


A novel prenylflavone restricts breast cancer cell growth through AhR-mediated destabilization of ERα protein.

Tiong CT, Chen C, Zhang SJ, Li J, Soshilov A, Denison MS, Lee LS, Tam VH, Wong SP, Xu HE, Yong EL.

Carcinogenesis. 2012 May;33(5):1089-97. doi: 10.1093/carcin/bgs110. Epub 2012 Feb 16.

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