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Items: 17

1.

Adenylyl cyclases in the digestive system.

Sabbatini ME, Gorelick F, Glaser S.

Cell Signal. 2014 Jun;26(6):1173-81. doi: 10.1016/j.cellsig.2014.01.033. Epub 2014 Feb 9. Review.

2.

Cholecystokinin-mediated RhoGDI phosphorylation via PKCα promotes both RhoA and Rac1 signaling.

Sabbatini ME, Williams JA.

PLoS One. 2013 Jun 11;8(6):e66029. doi: 10.1371/journal.pone.0066029. Print 2013.

3.

Adenylyl cyclase 6 mediates the action of cyclic AMP-dependent secretagogues in mouse pancreatic exocrine cells via protein kinase A pathway activation.

Sabbatini ME, D'Alecy L, Lentz SI, Tang T, Williams JA.

J Physiol. 2013 Aug 1;591(15):3693-707. doi: 10.1113/jphysiol.2012.249698. Epub 2013 Jun 10.

4.

Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain.

Chen Z, Guo L, Hadas J, Gutowski S, Sprang SR, Sternweis PC.

J Biol Chem. 2012 Jul 20;287(30):25490-500. doi: 10.1074/jbc.M111.333716. Epub 2012 Jun 1.

5.

Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13.

Kozasa T, Hajicek N, Chow CR, Suzuki N.

J Biochem. 2011 Oct;150(4):357-69. doi: 10.1093/jb/mvr105. Epub 2011 Aug 26. Review.

6.

Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex.

Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, Chow CR, Shirouzu M, Terada T, Patel M, Yokoyama S, Kozasa T.

J Biol Chem. 2011 Jun 10;286(23):20625-36. doi: 10.1074/jbc.M110.201392. Epub 2011 Apr 20.

7.

CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini.

Sabbatini ME, Bi Y, Ji B, Ernst SA, Williams JA.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C592-601. doi: 10.1152/ajpcell.00448.2009. Epub 2009 Nov 25.

8.

Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors.

Aittaleb M, Boguth CA, Tesmer JJ.

Mol Pharmacol. 2010 Feb;77(2):111-25. doi: 10.1124/mol.109.061234. Epub 2009 Oct 30. Review.

9.

On the mechanism of autoinhibition of the RhoA-specific nucleotide exchange factor PDZRhoGEF.

Zheng M, Cierpicki T, Momotani K, Artamonov MV, Derewenda U, Bushweller JH, Somlyo AV, Derewenda ZS.

BMC Struct Biol. 2009 May 21;9:36. doi: 10.1186/1472-6807-9-36.

10.

Differences in Galpha12- and Galpha13-mediated plasma membrane recruitment of p115-RhoGEF.

Bhattacharyya R, Banerjee J, Khalili K, Wedegaertner PB.

Cell Signal. 2009 Jun;21(6):996-1006. doi: 10.1016/j.cellsig.2009.02.010. Epub 2009 Feb 25.

11.

Regulation and physiological functions of G12/13-mediated signaling pathways.

Suzuki N, Hajicek N, Kozasa T.

Neurosignals. 2009;17(1):55-70. doi: 10.1159/000186690. Epub 2009 Feb 12. Review.

12.

Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.

Chen Z, Singer WD, Danesh SM, Sternweis PC, Sprang SR.

Structure. 2008 Oct 8;16(10):1532-43. doi: 10.1016/j.str.2008.07.009.

13.

Lsc activity is controlled by oligomerization and regulates integrin adhesion.

Hu J, Strauch P, Rubtsov A, Donovan EE, Pelanda R, Torres RM.

Mol Immunol. 2008 Apr;45(7):1825-36. Epub 2007 Dec 21.

14.

Galphaq directly activates p63RhoGEF and Trio via a conserved extension of the Dbl homology-associated pleckstrin homology domain.

Rojas RJ, Yohe ME, Gershburg S, Kawano T, Kozasa T, Sondek J.

J Biol Chem. 2007 Oct 5;282(40):29201-10. Epub 2007 Jul 2.

15.

The G12 family of heterotrimeric G proteins promotes breast cancer invasion and metastasis.

Kelly P, Moeller BJ, Juneja J, Booden MA, Der CJ, Daaka Y, Dewhirst MW, Fields TA, Casey PJ.

Proc Natl Acad Sci U S A. 2006 May 23;103(21):8173-8. Epub 2006 May 16.

16.

A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins.

Kreutz B, Yau DM, Nance MR, Tanabe S, Tesmer JJ, Kozasa T.

Biochemistry. 2006 Jan 10;45(1):167-74.

17.

Functional consequences of G alpha 13 mutations that disrupt interaction with p115RhoGEF.

Grabocka E, Wedegaertner PB.

Oncogene. 2005 Mar 24;24(13):2155-65.

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