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Items: 1 to 20 of 96

1.

PTH modulation of NCC activity regulates TRPV5 Ca2+ reabsorption.

Hoover RS, Tomilin V, Hanson L, Pochynyuk O, Ko B.

Am J Physiol Renal Physiol. 2016 Jan 15;310(2):F144-51. doi: 10.1152/ajprenal.00323.2015. Epub 2015 Nov 25.

PMID:
26608788
2.

A unifying mechanism for WNK kinase regulation of sodium-chloride cotransporter.

Huang CL, Cheng CJ.

Pflugers Arch. 2015 Nov;467(11):2235-41. doi: 10.1007/s00424-015-1708-2. Epub 2015 Apr 24.

PMID:
25904388
3.

Caveolin-1 Deficiency Inhibits the Basolateral K+ Channels in the Distal Convoluted Tubule and Impairs Renal K+ and Mg2+ Transport.

Wang L, Zhang C, Su X, Lin DH, Wang W.

J Am Soc Nephrol. 2015 Nov;26(11):2678-90. doi: 10.1681/ASN.2014070658. Epub 2015 Apr 6.

PMID:
25848073
4.

Revisiting the NaCl cotransporter regulation by with-no-lysine kinases.

Bazúa-Valenti S, Gamba G.

Am J Physiol Cell Physiol. 2015 May 15;308(10):C779-91. doi: 10.1152/ajpcell.00065.2015. Epub 2015 Mar 18. Review.

PMID:
25788573
5.

Mechanisms of angiotensin II stimulation of NCC are time-dependent in mDCT15 cells.

Ko B, Mistry A, Hanson L, Mallick R, Hoover RS.

Am J Physiol Renal Physiol. 2015 Apr 1;308(7):F720-7. doi: 10.1152/ajprenal.00465.2014. Epub 2015 Jan 28.

PMID:
25651566
6.

The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride.

Bazúa-Valenti S, Chávez-Canales M, Rojas-Vega L, González-Rodríguez X, Vázquez N, Rodríguez-Gama A, Argaiz ER, Melo Z, Plata C, Ellison DH, García-Valdés J, Hadchouel J, Gamba G.

J Am Soc Nephrol. 2015 Aug;26(8):1781-6. doi: 10.1681/ASN.2014050470. Epub 2014 Dec 26.

PMID:
25542968
7.

Hypertrophy in the Distal Convoluted Tubule of an 11β-Hydroxysteroid Dehydrogenase Type 2 Knockout Model.

Hunter RW, Ivy JR, Flatman PW, Kenyon CJ, Craigie E, Mullins LJ, Bailey MA, Mullins JJ.

J Am Soc Nephrol. 2015 Jul;26(7):1537-48. doi: 10.1681/ASN.2013060634. Epub 2014 Oct 27.

8.

Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation.

Shibata S, Arroyo JP, Castañeda-Bueno M, Puthumana J, Zhang J, Uchida S, Stone KL, Lam TT, Lifton RP.

Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15556-61. doi: 10.1073/pnas.1418342111. Epub 2014 Oct 13.

9.

Hypotonicity stimulates potassium flux through the WNK-SPAK/OSR1 kinase cascade and the Ncc69 sodium-potassium-2-chloride cotransporter in the Drosophila renal tubule.

Wu Y, Schellinger JN, Huang CL, Rodan AR.

J Biol Chem. 2014 Sep 19;289(38):26131-42. doi: 10.1074/jbc.M114.577767. Epub 2014 Aug 1.

10.

Distal convoluted tubule.

Subramanya AR, Ellison DH.

Clin J Am Soc Nephrol. 2014 Dec 5;9(12):2147-63. doi: 10.2215/CJN.05920613. Epub 2014 May 22. Review.

11.

WNK4 is the major WNK positively regulating NCC in the mouse kidney.

Takahashi D, Mori T, Nomura N, Khan MZ, Araki Y, Zeniya M, Sohara E, Rai T, Sasaki S, Uchida S.

Biosci Rep. 2014 May 9;34(3). pii: e00107. doi: 10.1042/BSR20140047.

12.

Regulation of with-no-lysine kinase signaling by Kelch-like proteins.

Uchida S, Sohara E, Rai T, Sasaki S.

Biol Cell. 2014 Feb;106(2):45-56. doi: 10.1111/boc.201300069. Epub 2014 Jan 10. Review.

13.

Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia.

Shibata S, Rinehart J, Zhang J, Moeckel G, Castañeda-Bueno M, Stiegler AL, Boggon TJ, Gamba G, Lifton RP.

Cell Metab. 2013 Nov 5;18(5):660-71. doi: 10.1016/j.cmet.2013.10.005.

14.

SPAK deficiency corrects pseudohypoaldosteronism II caused by WNK4 mutation.

Chu PY, Cheng CJ, Wu YC, Fang YW, Chau T, Uchida S, Sasaki S, Yang SS, Lin SH.

PLoS One. 2013 Sep 11;8(9):e72969. doi: 10.1371/journal.pone.0072969. eCollection 2013.

15.

The emerging family of CULLIN3-RING ubiquitin ligases (CRL3s): cellular functions and disease implications.

Genschik P, Sumara I, Lechner E.

EMBO J. 2013 Aug 28;32(17):2307-20. doi: 10.1038/emboj.2013.173. Epub 2013 Aug 2. Review.

16.

Aldosterone acutely stimulates NCC activity via a SPAK-mediated pathway.

Ko B, Mistry AC, Hanson L, Mallick R, Wynne BM, Thai TL, Bailey JL, Klein JD, Hoover RS.

Am J Physiol Renal Physiol. 2013 Sep 1;305(5):F645-52. doi: 10.1152/ajprenal.00053.2013. Epub 2013 Jun 5.

17.

Disease-causing mutations in KLHL3 impair its effect on WNK4 degradation.

Wu G, Peng JB.

FEBS Lett. 2013 Jun 19;587(12):1717-22. doi: 10.1016/j.febslet.2013.04.032. Epub 2013 May 9.

18.

Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4.

Shibata S, Zhang J, Puthumana J, Stone KL, Lifton RP.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7838-43. doi: 10.1073/pnas.1304592110. Epub 2013 Apr 1.

19.

Crystal structure of KLHL3 in complex with Cullin3.

Ji AX, Privé GG.

PLoS One. 2013;8(4):e60445. doi: 10.1371/journal.pone.0060445. Epub 2013 Apr 3.

20.

Renal tubular NEDD4-2 deficiency causes NCC-mediated salt-dependent hypertension.

Ronzaud C, Loffing-Cueni D, Hausel P, Debonneville A, Malsure SR, Fowler-Jaeger N, Boase NA, Perrier R, Maillard M, Yang B, Stokes JB, Koesters R, Kumar S, Hummler E, Loffing J, Staub O.

J Clin Invest. 2013 Feb;123(2):657-65. doi: 10.1172/JCI61110. Epub 2013 Jan 25.

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