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Cited In for PubMed (Select 12484746)


The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.

Swinnen E, Wilms T, Idkowiak-Baldys J, Smets B, De Snijder P, Accardo S, Ghillebert R, Thevissen K, Cammue B, De Vos D, Bielawski J, Hannun YA, Winderickx J.

Mol Biol Cell. 2014 Jan;25(1):196-211. doi: 10.1091/mbc.E13-06-0340. Epub 2013 Nov 6.


The synthetic amphipathic peptidomimetic LTX109 is a potent fungicide that disturbs plasma membrane integrity in a sphingolipid dependent manner.

Bojsen R, Torbensen R, Larsen CE, Folkesson A, Regenberg B.

PLoS One. 2013 Jul 12;8(7):e69483. doi: 10.1371/journal.pone.0069483. Print 2013.


Orm proteins integrate multiple signals to maintain sphingolipid homeostasis.

Gururaj C, Federman RS, Chang A.

J Biol Chem. 2013 Jul 12;288(28):20453-63. doi: 10.1074/jbc.M113.472860. Epub 2013 Jun 4. Erratum in: J Biol Chem. 2015 Jan 16;290(3):1455. Federman, Ross [corrected to Federman, Ross S].


Regulation of sphingolipid synthesis through Orm1 and Orm2 in yeast.

Liu M, Huang C, Polu SR, Schneiter R, Chang A.

J Cell Sci. 2012 May 15;125(Pt 10):2428-35. doi: 10.1242/jcs.100578. Epub 2012 Feb 10.


Down-regulating sphingolipid synthesis increases yeast lifespan.

Huang X, Liu J, Dickson RC.

PLoS Genet. 2012 Feb;8(2):e1002493. doi: 10.1371/journal.pgen.1002493. Epub 2012 Feb 2.


Conserved molecular mechanisms underlying homeostasis of the Golgi complex.

Wilson C, Ragnini-Wilson A.

Int J Cell Biol. 2010;2010:758230. doi: 10.1155/2010/758230. Epub 2010 Oct 3.


Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control.

Han S, Lone MA, Schneiter R, Chang A.

Proc Natl Acad Sci U S A. 2010 Mar 30;107(13):5851-6. doi: 10.1073/pnas.0911617107. Epub 2010 Mar 8.


Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine.

Skepper CK, Dalisay DS, Molinski TF.

Bioorg Med Chem Lett. 2010 Mar 15;20(6):2029-32. doi: 10.1016/j.bmcl.2010.01.068. Epub 2010 Feb 1.


Kei1: a novel subunit of inositolphosphorylceramide synthase, essential for its enzyme activity and Golgi localization.

Sato K, Noda Y, Yoda K.

Mol Biol Cell. 2009 Oct;20(20):4444-57. doi: 10.1091/mbc.E09-03-0235. Epub 2009 Sep 2.


The vascular S1P gradient-cellular sources and biological significance.

Hla T, Venkataraman K, Michaud J.

Biochim Biophys Acta. 2008 Sep;1781(9):477-82. doi: 10.1016/j.bbalip.2008.07.003. Epub 2008 Jul 28. Review.


Thematic review series: sphingolipids. New insights into sphingolipid metabolism and function in budding yeast.

Dickson RC.

J Lipid Res. 2008 May;49(5):909-21. doi: 10.1194/jlr.R800003-JLR200. Epub 2008 Feb 23. Review.


Yeast ARV1 is required for efficient delivery of an early GPI intermediate to the first mannosyltransferase during GPI assembly and controls lipid flow from the endoplasmic reticulum.

Kajiwara K, Watanabe R, Pichler H, Ihara K, Murakami S, Riezman H, Funato K.

Mol Biol Cell. 2008 May;19(5):2069-82. doi: 10.1091/mbc.E07-08-0740. Epub 2008 Feb 20.


Redirection of sphingolipid metabolism toward de novo synthesis of ethanolamine in Leishmania.

Zhang K, Pompey JM, Hsu FF, Key P, Bandhuvula P, Saba JD, Turk J, Beverley SM.

EMBO J. 2007 Feb 21;26(4):1094-104. Epub 2007 Feb 8.


Sphingoid base is required for translation initiation during heat stress in Saccharomyces cerevisiae.

Meier KD, Deloche O, Kajiwara K, Funato K, Riezman H.

Mol Biol Cell. 2006 Mar;17(3):1164-75. Epub 2005 Dec 28.


A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast.

Proszynski TJ, Klemm RW, Gravert M, Hsu PP, Gloor Y, Wagner J, Kozak K, Grabner H, Walzer K, Bagnat M, Simons K, Walch-Solimena C.

Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):17981-6. Epub 2005 Dec 5.


Functional analysis of CaIPT1, a sphingolipid biosynthetic gene involved in multidrug resistance and morphogenesis of Candida albicans.

Prasad T, Saini P, Gaur NA, Vishwakarma RA, Khan LA, Haq QM, Prasad R.

Antimicrob Agents Chemother. 2005 Aug;49(8):3442-52.


Lip1p: a novel subunit of acyl-CoA ceramide synthase.

Vallée B, Riezman H.

EMBO J. 2005 Feb 23;24(4):730-41. Epub 2005 Feb 3.


Mutagenesis of the putative sterol-sensing domain of yeast Niemann Pick C-related protein reveals a primordial role in subcellular sphingolipid distribution.

Malathi K, Higaki K, Tinkelenberg AH, Balderes DA, Almanzar-Paramio D, Wilcox LJ, Erdeniz N, Redican F, Padamsee M, Liu Y, Khan S, Alcantara F, Carstea ED, Morris JA, Sturley SL.

J Cell Biol. 2004 Feb 16;164(4):547-56.


Sphingolipids are essential for differentiation but not growth in Leishmania.

Zhang K, Showalter M, Revollo J, Hsu FF, Turk J, Beverley SM.

EMBO J. 2003 Nov 17;22(22):6016-26.

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