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Results: 1 to 20 of 29

1.
2.

Palladium-catalyzed transformations of salvinorin A, a neoclerodane diterpene from Salvia divinorum.

Riley AP, Day VW, Navarro HA, Prisinzano TE.

Org Lett. 2013 Dec 6;15(23):5936-9. doi: 10.1021/ol4027528. Epub 2013 Nov 18.

PMID:
24246026
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mechanistic and computational studies of exocyclic stereocontrol in the synthesis of bryostatin-like cis-2,6-disubstituted 4-alkylidenetetrahydropyrans by Prins cyclization.

Ogawa Y, Painter PP, Tantillo DJ, Wender PA.

J Org Chem. 2013 Jan 4;78(1):104-15. doi: 10.1021/jo301953h. Epub 2012 Nov 7.

PMID:
23121542
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Designed, synthetically accessible bryostatin analogues potently induce activation of latent HIV reservoirs in vitro.

DeChristopher BA, Loy BA, Marsden MD, Schrier AJ, Zack JA, Wender PA.

Nat Chem. 2012 Sep;4(9):705-10. doi: 10.1038/nchem.1395. Epub 2012 Jul 15.

PMID:
22914190
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis.

Wender PA, Loy BA, Schrier AJ.

Isr J Chem. 2011 Apr 1;51(3-4):453-472. Epub 2011 Mar 24.

PMID:
22661768
[PubMed]
Free PMC Article
6.

Bryostatin analogue-induced apoptosis in mantle cell lymphoma cell lines.

Lopez-Campistrous A, Song X, Schrier AJ, Wender PA, Dower NA, Stone JC.

Exp Hematol. 2012 Aug;40(8):646-56.e2. doi: 10.1016/j.exphem.2012.03.002. Epub 2012 Mar 28.

PMID:
22465296
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

"Picolog," a synthetically-available bryostatin analog, inhibits growth of MYC-induced lymphoma in vivo.

DeChristopher BA, Fan AC, Felsher DW, Wender PA.

Oncotarget. 2012 Jan;3(1):58-66.

PMID:
22308267
[PubMed - indexed for MEDLINE]
Free PMC Article
8.
9.

Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues.

Smith AB 3rd, Hogan AM, Liu Z, Razler TM, Meis RM, Morinaka BI, Molinski TF.

Tetrahedron. 2011 Jul 8;67(27-28):5069-5078.

PMID:
21811346
[PubMed]
Free PMC Article
10.

Total syntheses of bryostatins: synthesis of two ring-expanded bryostatin analogues and the development of a new-generation strategy to access the C7-C27 fragment.

Trost BM, Yang H, Dong G.

Chemistry. 2011 Aug 22;17(35):9789-805. doi: 10.1002/chem.201002932. Epub 2011 Jul 21.

PMID:
21780195
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Regulation and Function of the RasGRP Family of Ras Activators in Blood Cells.

Stone JC.

Genes Cancer. 2011 Mar;2(3):320-34. doi: 10.1177/1947601911408082.

PMID:
21779502
[PubMed]
Free PMC Article
12.

Design, synthesis, and biological evaluation of diminutive forms of (+)-spongistatin 1: lessons learned.

Smith AB 3rd, Risatti CA, Atasoylu O, Bennett CS, Liu J, Cheng H, TenDyke K, Xu Q.

J Am Chem Soc. 2011 Sep 7;133(35):14042-53. doi: 10.1021/ja2046167. Epub 2011 Aug 12.

PMID:
21761891
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Total synthesis of bryostatin 9.

Wender PA, Schrier AJ.

J Am Chem Soc. 2011 Jun 22;133(24):9228-31. doi: 10.1021/ja203034k. Epub 2011 May 27.

PMID:
21618969
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Design, synthesis, and evaluation of potent bryostatin analogs that modulate PKC translocation selectivity.

Wender PA, Baryza JL, Brenner SE, DeChristopher BA, Loy BA, Schrier AJ, Verma VA.

Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6721-6. doi: 10.1073/pnas.1015270108. Epub 2011 Mar 17.

PMID:
21415363
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Prins-type macrocyclizations as an efficient ring-closing strategy in natural product synthesis.

Crane EA, Scheidt KA.

Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8316-26. doi: 10.1002/anie.201002809. Review.

PMID:
20931580
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

An enantioselective total synthesis of (+)-peloruside A.

McGowan MA, Stevenson CP, Schiffler MA, Jacobsen EN.

Angew Chem Int Ed Engl. 2010 Aug 16;49(35):6147-50. doi: 10.1002/anie.201002177. No abstract available.

PMID:
20586089
[PubMed - in process]
Free PMC Article
17.

Molecular modeling, total synthesis, and biological evaluations of C9-deoxy bryostatin 1.

Keck GE, Poudel YB, Rudra A, Stephens JC, Kedei N, Lewin NE, Peach ML, Blumberg PM.

Angew Chem Int Ed Engl. 2010 Jun 21;49(27):4580-4. doi: 10.1002/anie.201001200. No abstract available.

PMID:
20491108
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Challenges in the synthesis of a unique mono-carboxylic acid antibiotic, (+)-zincophorin.

Song Z, Lohse AG, Hsung RP.

Nat Prod Rep. 2009 Apr;26(4):560-71. Review.

PMID:
19642422
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Hemi-phorboxazole a: structure confirmation, analogue design and biological evaluation.

Smith AB 3rd, Liu Z, Hogan AM, Dalisay DS, Molinski TF.

Org Lett. 2009 Aug 20;11(16):3766-9. doi: 10.1021/ol9014317.

PMID:
19637861
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The bryostatin 1 A-ring acetate is not the critical determinant for antagonism of phorbol ester-induced biological responses.

Keck GE, Li W, Kraft MB, Kedei N, Lewin NE, Blumberg PM.

Org Lett. 2009 Jun 4;11(11):2277-80. doi: 10.1021/ol900585t.

PMID:
19419164
[PubMed - indexed for MEDLINE]
Free PMC Article
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