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Items: 19


Hypoxia Induces Epithelial-Mesenchymal Transition in Follicular Thyroid Cancer: Involvement of Regulation of Twist by Hypoxia Inducible Factor-1α.

Yang YJ, Na HJ, Suh MJ, Ban MJ, Byeon HK, Kim WS, Kim JW, Choi EC, Kwon HJ, Chang JW, Koh YW.

Yonsei Med J. 2015 Nov;56(6):1503-14. doi: 10.3349/ymj.2015.56.6.1503.


Mouse models of thyroid cancer: A 2015 update.

Kirschner LS, Qamri Z, Kari S, Ashtekar A.

Mol Cell Endocrinol. 2016 Feb 5;421:18-27. doi: 10.1016/j.mce.2015.06.029. Epub 2015 Jun 27.


Molecular pathways associated with aggressiveness of papillary thyroid cancer.

Benvenga S, Koch CA.

Curr Genomics. 2014 Jun;15(3):162-70. doi: 10.2174/1389202915999140404100958.


Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.

Pringle DR, Vasko VV, Yu L, Manchanda PK, Lee AA, Zhang X, Kirschner JM, Parlow AF, Saji M, Jarjoura D, Ringel MD, La Perle KM, Kirschner LS.

J Clin Endocrinol Metab. 2014 May;99(5):E804-12. doi: 10.1210/jc.2013-3101. Epub 2014 Feb 10.


Thyroid-specific ablation of the Carney complex gene, PRKAR1A, results in hyperthyroidism and follicular thyroid cancer.

Pringle DR, Yin Z, Lee AA, Manchanda PK, Yu L, Parlow AF, Jarjoura D, La Perle KM, Kirschner LS.

Endocr Relat Cancer. 2012 May 24;19(3):435-46. doi: 10.1530/ERC-11-0306. Print 2012 Jun.


PRKAR1A gene analysis and protein kinase A activity in endometrial tumors.

Tsigginou A, Bimpaki E, Nesterova M, Horvath A, Boikos S, Lyssikatos C, Papageorgiou C, Dimitrakakis C, Rodolakis A, Stratakis CA, Antsaklis A.

Endocr Relat Cancer. 2012 Jun 18;19(4):457-62. doi: 10.1530/ERC-11-0328. Print 2012 Aug.


Thyroid cancer: current molecular perspectives.

Giusti F, Falchetti A, Franceschelli F, Marini F, Tanini A, Brandi ML.

J Oncol. 2010;2010:351679. doi: 10.1155/2010/351679. Epub 2010 Mar 29.


Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update.

Horvath A, Bertherat J, Groussin L, Guillaud-Bataille M, Tsang K, Cazabat L, Libé R, Remmers E, René-Corail F, Faucz FR, Clauser E, Calender A, Bertagna X, Carney JA, Stratakis CA.

Hum Mutat. 2010 Apr;31(4):369-79. doi: 10.1002/humu.21178.


Protein kinase A and B-Raf mediate extracellular signal-regulated kinase activation by thyrotropin.

Vuchak LA, Tsygankova OM, Prendergast GV, Meinkoth JL.

Mol Pharmacol. 2009 Nov;76(5):1123-9. doi: 10.1124/mol.109.060129. Epub 2009 Aug 31.


Regulation of actin function by protein kinase A-mediated phosphorylation of Limk1.

Nadella KS, Saji M, Jacob NK, Pavel E, Ringel MD, Kirschner LS.

EMBO Rep. 2009 Jun;10(6):599-605. doi: 10.1038/embor.2009.58. Epub 2009 May 8. Erratum in: EMBO Rep. 2009 Sep;10(9):1066.


Ectopic thymus presenting as a thyroid nodule in a patient with the Carney complex.

Courcoutsakis N, Patronas N, Filie AC, Carney JA, Moraitis A, Stratakis CA.

Thyroid. 2009 Mar;19(3):293-6. doi: 10.1089/thy.2008.0404.


Transcriptional patterns, biomarkers and pathways characterizing nasopharyngeal carcinoma of Southern China.

Fang W, Li X, Jiang Q, Liu Z, Yang H, Wang S, Xie S, Liu Q, Liu T, Huang J, Xie W, Li Z, Zhao Y, Wang E, Marincola FM, Yao K.

J Transl Med. 2008 Jun 20;6:32. doi: 10.1186/1479-5876-6-32.


Dysregulation of the phosphatidylinositol 3-kinase pathway in thyroid neoplasia.

Paes JE, Ringel MD.

Endocrinol Metab Clin North Am. 2008 Jun;37(2):375-87, viii-ix. doi: 10.1016/j.ecl.2008.01.001. Review.


Protein kinase A effects of an expressed PRKAR1A mutation associated with aggressive tumors.

Meoli E, Bossis I, Cazabat L, Mavrakis M, Horvath A, Stergiopoulos S, Shiferaw ML, Fumey G, Perlemoine K, Muchow M, Robinson-White A, Weinberg F, Nesterova M, Patronas Y, Groussin L, Bertherat J, Stratakis CA.

Cancer Res. 2008 May 1;68(9):3133-41. doi: 10.1158/0008-5472.CAN-08-0064.


Targeted deletion of Prkar1a reveals a role for protein kinase A in mesenchymal-to-epithelial transition.

Nadella KS, Jones GN, Trimboli A, Stratakis CA, Leone G, Kirschner LS.

Cancer Res. 2008 Apr 15;68(8):2671-7. doi: 10.1158/0008-5472.CAN-07-6002.


Haploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and men.

Burton KA, McDermott DA, Wilkes D, Poulsen MN, Nolan MA, Goldstein M, Basson CT, McKnight GS.

Mol Endocrinol. 2006 Oct;20(10):2504-13. Epub 2006 May 25.


The lentiginoses: cutaneous markers of systemic disease and a window to new aspects of tumourigenesis.

Bauer AJ, Stratakis CA.

J Med Genet. 2005 Nov;42(11):801-10. Epub 2005 Jun 15. Review.


A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A induced lesions.

Griffin KJ, Kirschner LS, Matyakhina L, Stergiopoulos SG, Robinson-White A, Lenherr SM, Weinberg FD, Claflin ES, Batista D, Bourdeau I, Voutetakis A, Sandrini F, Meoli EM, Bauer AJ, Cho-Chung YS, Bornstein SR, Carney JA, Stratakis CA.

J Med Genet. 2004 Dec;41(12):923-31.


Gene expression profiling during all-trans retinoic acid-induced cell differentiation of acute promyelocytic leukemia cells.

Yang L, Zhao H, Li SW, Ahrens K, Collins C, Eckenrode S, Ruan QG, McIndoe RA, She JX.

J Mol Diagn. 2003 Nov;5(4):212-21.

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