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Current Evidence for a Role of the Kynurenine Pathway of Tryptophan Metabolism in Multiple Sclerosis.

Lovelace MD, Varney B, Sundaram G, Franco NF, Ng ML, Pai S, Lim CK, Guillemin GJ, Brew BJ.

Front Immunol. 2016 Aug 4;7:246. doi: 10.3389/fimmu.2016.00246. eCollection 2016. Review.


Zinc Induces Dendritic Cell Tolerogenic Phenotype and Skews Regulatory T Cell-Th17 Balance.

George MM, Subramanian Vignesh K, Landero Figueroa JA, Caruso JA, Deepe GS Jr.

J Immunol. 2016 Sep 1;197(5):1864-76. doi: 10.4049/jimmunol.1600410. Epub 2016 Jul 27.


The end of the road for the tryptophan depletion concept in pregnancy and infection.

Badawy AA, Namboodiri AM, Moffett JR.

Clin Sci (Lond). 2016 Aug 1;130(15):1327-33. doi: 10.1042/CS20160153.


Elevated interleukin-27 levels in human neonatal macrophages regulate indoleamine dioxygenase in a STAT-1 and STAT-3-dependent manner.

Jung JY, Gleave Parson M, Kraft JD, Lyda L, Kobe B, Davis C, Robinson J, Peña MM, Robinson CM.

Immunology. 2016 Sep;149(1):35-47. doi: 10.1111/imm.12625.


The effect of kynurenic acid on the synthesis of selected cytokines by murine splenocytes - in vitro and ex vivo studies.

Małaczewska J, Siwicki AK, Wójcik RM, Turski WA, Kaczorek E.

Cent Eur J Immunol. 2016;41(1):39-46. doi: 10.5114/ceji.2016.58815. Epub 2016 Mar 24.


Carbon Disulfide (CS2) Interference in Glucose Metabolism from Unconventional Oil and Gas Extraction and Processing Emissions.

Rich AL, Patel JT, Al-Angari SS.

Environ Health Insights. 2016 Mar 28;10:51-7. doi: 10.4137/EHI.S31906. eCollection 2016.


Metabolism Is Central to Tolerogenic Dendritic Cell Function.

Sim WJ, Ahl PJ, Connolly JE.

Mediators Inflamm. 2016;2016:2636701. doi: 10.1155/2016/2636701. Epub 2016 Feb 11. Review.


Generation of Tolerogenic Dendritic Cells and Their Therapeutic Applications.

Yoo S, Ha SJ.

Immune Netw. 2016 Feb;16(1):52-60. doi: 10.4110/in.2016.16.1.52. Epub 2016 Feb 25. Review.


Mesenchymal stem cells and immunomodulation: current status and future prospects.

Gao F, Chiu SM, Motan DA, Zhang Z, Chen L, Ji HL, Tse HF, Fu QL, Lian Q.

Cell Death Dis. 2016 Jan 21;7:e2062. doi: 10.1038/cddis.2015.327. Review.


Tolerogenic effect of mouse fibroblasts on dendritic cells.

Khosravi-Maharlooei M, Pakyari M, Jalili RB, Salimi-Elizei S, Lai JC, Poormasjedi-Meibod M, Kilani RT, Dutz J, Ghahary A.

Immunology. 2016 May;148(1):22-33. doi: 10.1111/imm.12584. Epub 2016 Feb 8.


Innate and adaptive immunity in the development of depression: An update on current knowledge and technological advances.

Haapakoski R, Ebmeier KP, Alenius H, Kivimäki M.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Apr 3;66:63-72. doi: 10.1016/j.pnpbp.2015.11.012. Epub 2015 Nov 26. Review.


Severity of DSS-induced colitis is reduced in Ido1-deficient mice with down-regulation of TLR-MyD88-NF-kB transcriptional networks.

Shon WJ, Lee YK, Shin JH, Choi EY, Shin DM.

Sci Rep. 2015 Nov 27;5:17305. doi: 10.1038/srep17305.


Impact of Diverse Immune Evasion Mechanisms of Cancer Cells on T Cells Engaged by EpCAM/CD3-Bispecific Antibody Construct AMG 110.

Deisting W, Raum T, Kufer P, Baeuerle PA, Münz M.

PLoS One. 2015 Oct 28;10(10):e0141669. doi: 10.1371/journal.pone.0141669. eCollection 2015.


Immunometabolism within the tuberculosis granuloma: amino acids, hypoxia, and cellular respiration.

Qualls JE, Murray PJ.

Semin Immunopathol. 2016 Mar;38(2):139-52. doi: 10.1007/s00281-015-0534-0. Epub 2015 Oct 21.


Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development.

Cole JE, Astola N, Cribbs AP, Goddard ME, Park I, Green P, Davies AH, Williams RO, Feldmann M, Monaco C.

Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13033-8. doi: 10.1073/pnas.1517820112. Epub 2015 Oct 5.


Tryptophan metabolism, disposition and utilization in pregnancy.

Badawy AA.

Biosci Rep. 2015 Sep 17;35(5). pii: e00261. doi: 10.1042/BSR20150197. Review.


The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity.

Mbongue JC, Nicholas DA, Torrez TW, Kim NS, Firek AF, Langridge WH.

Vaccines (Basel). 2015 Sep 10;3(3):703-29. doi: 10.3390/vaccines3030703. Review.


Abatacept decreases disease activity in a absence of CD4(+) T cells in a collagen-induced arthritis model.

Jansen DT, el Bannoudi H, Arens R, Habets KL, Hameetman M, Huizinga TW, Stoop JN, Toes RE.

Arthritis Res Ther. 2015 Aug 20;17:220. doi: 10.1186/s13075-015-0731-1.


The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy.

Zhai L, Dey M, Lauing KL, Gritsina G, Kaur R, Lukas RV, Nicholas MK, Rademaker AW, Dostal CR, McCusker RH, Raizer JJ, Parsa AT, Bloch O, Wainwright DA.

J Clin Neurosci. 2015 Dec;22(12):1964-8. doi: 10.1016/j.jocn.2015.06.018. Epub 2015 Aug 14.

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