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Results: 1 to 20 of 31

1.

High frequency of rare variants with a moderate-to-high predicted biological effect in protocadherin genes of extremely obese.

Mariman EC, Bouwman FG, Aller EE, van Baak MA, Wang P.

Genes Nutr. 2014 May;9(3):399. doi: 10.1007/s12263-014-0399-1. Epub 2014 Mar 30.

PMID:
24682882
[PubMed]
Free PMC Article
2.

The regulated secretory pathway and human disease: insights from gene variants and single nucleotide polymorphisms.

Lin WJ, Salton SR.

Front Endocrinol (Lausanne). 2013 Aug 6;4:96. doi: 10.3389/fendo.2013.00096. eCollection 2013.

PMID:
23964269
[PubMed]
Free PMC Article
3.

The biology of FTO: from nucleic acid demethylase to amino acid sensor.

Gulati P, Yeo GS.

Diabetologia. 2013 Oct;56(10):2113-21. doi: 10.1007/s00125-013-2999-5. Epub 2013 Jul 30. Review.

PMID:
23896822
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Pathogenesis of the metabolic syndrome: insights from monogenic disorders.

Murphy R, Carroll RW, Krebs JD.

Mediators Inflamm. 2013;2013:920214. doi: 10.1155/2013/920214. Epub 2013 May 21. Review.

PMID:
23766565
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Obesity induces hypothalamic endoplasmic reticulum stress and impairs proopiomelanocortin (POMC) post-translational processing.

Cakir I, Cyr NE, Perello M, Litvinov BP, Romero A, Stuart RC, Nillni EA.

J Biol Chem. 2013 Jun 14;288(24):17675-88. doi: 10.1074/jbc.M113.475343. Epub 2013 May 2.

PMID:
23640886
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

The genetics of human obesity.

Xia Q, Grant SF.

Ann N Y Acad Sci. 2013 Apr;1281:178-90. doi: 10.1111/nyas.12020. Epub 2013 Jan 29. Review.

PMID:
23360386
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mechanisms by which the orexigen NPY regulates anorexigenic α-MSH and TRH.

Cyr NE, Toorie AM, Steger JS, Sochat MM, Hyner S, Perello M, Stuart R, Nillni EA.

Am J Physiol Endocrinol Metab. 2013 Mar 15;304(6):E640-50. doi: 10.1152/ajpendo.00448.2012. Epub 2013 Jan 15.

PMID:
23321476
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderly.

Tranah GJ, Lam ET, Katzman SM, Nalls MA, Zhao Y, Evans DS, Yokoyama JS, Pawlikowska L, Kwok PY, Mooney S, Kritchevsky S, Goodpaster BH, Newman AB, Harris TB, Manini TM, Cummings SR; Health, Aging and Body Composition Study.

Biochim Biophys Acta. 2012 Sep;1817(9):1691-700. Epub 2012 May 31.

PMID:
22659402
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More?

Cheung MK, Yeo GS.

Front Endocrinol (Lausanne). 2011 Feb 22;2:4. doi: 10.3389/fendo.2011.00004. eCollection 2011.

PMID:
22649359
[PubMed]
Free PMC Article
10.

A novel missense mutation in the signal peptide of the human POMC gene: a possible additional link between early-onset type 2 diabetes and obesity.

Mencarelli M, Zulian A, Cancello R, Alberti L, Gilardini L, Di Blasio AM, Invitti C.

Eur J Hum Genet. 2012 Dec;20(12):1290-4. doi: 10.1038/ejhg.2012.103. Epub 2012 May 30.

PMID:
22643178
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity.

Creemers JW, Choquet H, Stijnen P, Vatin V, Pigeyre M, Beckers S, Meulemans S, Than ME, Yengo L, Tauber M, Balkau B, Elliott P, Jarvelin MR, Van Hul W, Van Gaal L, Horber F, Pattou F, Froguel P, Meyre D.

Diabetes. 2012 Feb;61(2):383-90. doi: 10.2337/db11-0305. Epub 2011 Dec 30.

PMID:
22210313
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Pediatric obesity: etiology and treatment.

Crocker MK, Yanovski JA.

Pediatr Clin North Am. 2011 Oct;58(5):1217-40, xi. doi: 10.1016/j.pcl.2011.07.004. Review.

PMID:
21981957
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

A genome-wide association study of aging.

Walter S, Atzmon G, Demerath EW, Garcia ME, Kaplan RC, Kumari M, Lunetta KL, Milaneschi Y, Tanaka T, Tranah GJ, Völker U, Yu L, Arnold A, Benjamin EJ, Biffar R, Buchman AS, Boerwinkle E, Couper D, De Jager PL, Evans DA, Harris TB, Hoffmann W, Hofman A, Karasik D, Kiel DP, Kocher T, Kuningas M, Launer LJ, Lohman KK, Lutsey PL, Mackenbach J, Marciante K, Psaty BM, Reiman EM, Rotter JI, Seshadri S, Shardell MD, Smith AV, van Duijn C, Walston J, Zillikens MC, Bandinelli S, Baumeister SE, Bennett DA, Ferrucci L, Gudnason V, Kivimaki M, Liu Y, Murabito JM, Newman AB, Tiemeier H, Franceschini N.

Neurobiol Aging. 2011 Nov;32(11):2109.e15-28. doi: 10.1016/j.neurobiolaging.2011.05.026. Epub 2011 Jul 22.

PMID:
21782286
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Hypothalamic proopiomelanocortin processing and the regulation of energy balance.

Wardlaw SL.

Eur J Pharmacol. 2011 Jun 11;660(1):213-9. doi: 10.1016/j.ejphar.2010.10.107. Epub 2011 Jan 3. Review.

PMID:
21208604
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Interactions of the melanocortin-4 receptor with the peptide agonist NDP-MSH.

Chapman KL, Kinsella GK, Cox A, Donnelly D, Findlay JB.

J Mol Biol. 2010 Aug 20;401(3):433-50. doi: 10.1016/j.jmb.2010.06.028. Epub 2010 Jun 19.

PMID:
20600126
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Childhood obesity.

Han JC, Lawlor DA, Kimm SY.

Lancet. 2010 May 15;375(9727):1737-48. doi: 10.1016/S0140-6736(10)60171-7. Epub 2010 May 5. Review.

PMID:
20451244
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

From monogenic to polygenic obesity: recent advances.

Hinney A, Vogel CI, Hebebrand J.

Eur Child Adolesc Psychiatry. 2010 Mar;19(3):297-310. doi: 10.1007/s00787-010-0096-6. Epub 2010 Feb 3. Review.

PMID:
20127379
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Analysis of the SIM1 contribution to polygenic obesity in the French population.

Ghoussaini M, Stutzmann F, Couturier C, Vatin V, Durand E, Lecoeur C, Degraeve F, Heude B, Tauber M, Hercberg S, Levy-Marchal C, Tounian P, Weill J, Traurig M, Bogardus C, Baier LJ, Michaud JL, Froguel P, Meyre D.

Obesity (Silver Spring). 2010 Aug;18(8):1670-5. doi: 10.1038/oby.2009.468. Epub 2010 Jan 14.

PMID:
20075856
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Regulation of the hypothalamic thyrotropin releasing hormone (TRH) neuron by neuronal and peripheral inputs.

Nillni EA.

Front Neuroendocrinol. 2010 Apr;31(2):134-56. doi: 10.1016/j.yfrne.2010.01.001. Epub 2010 Jan 13. Review.

PMID:
20074584
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Drug-induced and genetic alterations in stress-responsive systems: Implications for specific addictive diseases.

Zhou Y, Proudnikov D, Yuferov V, Kreek MJ.

Brain Res. 2010 Feb 16;1314:235-52. doi: 10.1016/j.brainres.2009.11.015. Epub 2009 Nov 12. Review.

PMID:
19914222
[PubMed - indexed for MEDLINE]
Free PMC Article

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