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Items: 1 to 20 of 62


The hypocretins (orexins) mediate the "phasic" components of REM sleep: A new hypothesis.

Torterolo P, Chase MH.

Sleep Sci. 2014 Mar;7(1):19-29. doi: 10.1016/j.slsci.2014.07.021. Epub 2014 Aug 20.


Understanding how discrete populations of hypothalamic neurons orchestrate complicated behavioral states.

Graebner AK, Iyer M, Carter ME.

Front Syst Neurosci. 2015 Aug 4;9:111. doi: 10.3389/fnsys.2015.00111. eCollection 2015. Review.


The orexin neuropeptide system: physical activity and hypothalamic function throughout the aging process.

Zink AN, Perez-Leighton CE, Kotz CM.

Front Syst Neurosci. 2014 Nov 4;8:211. doi: 10.3389/fnsys.2014.00211. eCollection 2014. Review.


Role of orexin in respiratory and sleep homeostasis during upper airway obstruction in rats.

Tarasiuk A, Levi A, Berdugo-Boura N, Yahalom A, Segev Y.

Sleep. 2014 May 1;37(5):987-98. doi: 10.5665/sleep.3676.


Inflammation-sleep interface in brain disease: TNF, insulin, orexin.

Clark IA, Vissel B.

J Neuroinflammation. 2014 Mar 21;11:51. doi: 10.1186/1742-2094-11-51. Review.


Orexin receptor antagonists as therapeutic agents for insomnia.

Equihua AC, De La Herrán-Arita AK, Drucker-Colin R.

Front Pharmacol. 2013 Dec 25;4:163. doi: 10.3389/fphar.2013.00163. Review.


Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators.

Ramirez AD, Gotter AL, Fox SV, Tannenbaum PL, Yao L, Tye SJ, McDonald T, Brunner J, Garson SL, Reiss DR, Kuduk SD, Coleman PJ, Uslaner JM, Hodgson R, Browne SE, Renger JJ, Winrow CJ.

Front Neurosci. 2013 Dec 24;7:254. doi: 10.3389/fnins.2013.00254. eCollection 2013.


Relation of melanin concentrating hormone levels to sleep, emotion and hypocretin levels.

Blouin AM, Siegel JM.

Sleep. 2013 Dec 1;36(12):1777. doi: 10.5665/sleep.3194. No abstract available.


Treating hypertension by targeting orexin receptors: potential effects on the sleep-related blood pressure dipping profile.

Silvani A, Bastianini S, Berteotti C, Lo Martire V, Zoccoli G.

J Physiol. 2013 Dec 1;591(Pt 23):6115-6. doi: 10.1113/jphysiol.2013.265504. No abstract available.


Sex differences in circadian timing systems: implications for disease.

Bailey M, Silver R.

Front Neuroendocrinol. 2014 Jan;35(1):111-39. doi: 10.1016/j.yfrne.2013.11.003. Epub 2013 Nov 25. Review.


The hypocretins/orexins: integrators of multiple physiological functions.

Li J, Hu Z, de Lecea L.

Br J Pharmacol. 2014 Jan;171(2):332-50. doi: 10.1111/bph.12415. Review.


Role of the locus coeruleus in enhanced orexin A-induced spontaneous physical activity in obesity-resistant rats.

Teske JA, Perez-Leighton CE, Billington CJ, Kotz CM.

Am J Physiol Regul Integr Comp Physiol. 2013 Dec;305(11):R1337-45. doi: 10.1152/ajpregu.00229.2013. Epub 2013 Oct 2.


Ghrelin-immunopositive hypothalamic neurons tie the circadian clock and visual system to the lateral hypothalamic arousal center.

Horvath TL, Abizaid A, Dietrich MO, Li Y, Takahashi JS, Bass J.

Mol Metab. 2012 Aug 18;1(1-2):79-85. doi: 10.1016/j.molmet.2012.08.003. eCollection 2012.


Quantitative electroencephalography within sleep/wake states differentiates GABAA modulators eszopiclone and zolpidem from dual orexin receptor antagonists in rats.

Fox SV, Gotter AL, Tye SJ, Garson SL, Savitz AT, Uslaner JM, Brunner JI, Tannenbaum PL, McDonald TP, Hodgson R, Yao L, Bowlby MR, Kuduk SD, Coleman PJ, Hargreaves R, Winrow CJ, Renger JJ.

Neuropsychopharmacology. 2013 Nov;38(12):2401-8. doi: 10.1038/npp.2013.139. Epub 2013 May 31.


Control of arousal by the orexin neurons.

Alexandre C, Andermann ML, Scammell TE.

Curr Opin Neurobiol. 2013 Oct;23(5):752-9. doi: 10.1016/j.conb.2013.04.008. Epub 2013 May 15. Review.


Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction.

Blouin AM, Fried I, Wilson CL, Staba RJ, Behnke EJ, Lam HA, Maidment NT, Karlsson KÆ, Lapierre JL, Siegel JM.

Nat Commun. 2013;4:1547. doi: 10.1038/ncomms2461.


Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of rodents: an in vitro study.

Sims RE, Wu HH, Dale N.

PLoS One. 2013;8(1):e53814. doi: 10.1371/journal.pone.0053814. Epub 2013 Jan 11.


Glutamate and GABA as rapid effectors of hypothalamic "peptidergic" neurons.

Schöne C, Burdakov D.

Front Behav Neurosci. 2012 Nov 26;6:81. doi: 10.3389/fnbeh.2012.00081. eCollection 2012.


Neuropharmacology of Sleep and Wakefulness: 2012 Update.

Watson CJ, Baghdoyan HA, Lydic R.

Sleep Med Clin. 2012 Sep 1;7(3):469-486. Epub 2012 Sep 4.


Hypocretinergic and non-hypocretinergic projections from the hypothalamus to the REM sleep executive area of the pons.

Torterolo P, Sampogna S, Chase MH.

Brain Res. 2013 Jan 23;1491:68-77. doi: 10.1016/j.brainres.2012.10.050. Epub 2012 Oct 30.

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