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Results: 1 to 20 of 106

1.

NL-103, a novel dual-targeted inhibitor of histone deacetylases and hedgehog pathway, effectively overcomes vismodegib resistance conferred by Smo mutations.

Zhao J, Quan H, Xie C, Lou L.

Pharmacol Res Perspect. 2014 Jun;2(3):e00043. doi: 10.1002/prp2.43. Epub 2014 Apr 7.

PMID:
25505589
[PubMed]
Free PMC Article
2.

CDO, an Hh-coreceptor, mediates lung cancer cell proliferation and tumorigenicity through Hedgehog signaling.

Leem YE, Ha HL, Bae JH, Baek KH, Kang JS.

PLoS One. 2014 Nov 4;9(11):e111701. doi: 10.1371/journal.pone.0111701. eCollection 2014.

PMID:
25369201
[PubMed - in process]
Free PMC Article
3.

Advances in managing medulloblastoma and intracranial primitive neuro-ectodermal tumors.

Adamski J, Ramaswamy V, Huang A, Bouffet E.

F1000Prime Rep. 2014 Jul 8;6:56. doi: 10.12703/P6-56. eCollection 2014. Review.

PMID:
25184046
[PubMed]
Free PMC Article
4.

MXD3 regulation of DAOY cell proliferation dictated by time course of activation.

Ngo T, Barisone GA, Lam KS, Dίaz E.

BMC Cell Biol. 2014 Jul 23;15:30. doi: 10.1186/1471-2121-15-30.

PMID:
25053245
[PubMed - in process]
Free PMC Article
5.

Cancer stem cells: biological functions and therapeutically targeting.

Ciurea ME, Georgescu AM, Purcaru SO, Artene SA, Emami GH, Boldeanu MV, Tache DE, Dricu A.

Int J Mol Sci. 2014 May 9;15(5):8169-85. doi: 10.3390/ijms15058169.

PMID:
24821540
[PubMed - in process]
Free PMC Article
6.

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort.

Pietsch T, Schmidt R, Remke M, Korshunov A, Hovestadt V, Jones DT, Felsberg J, Kaulich K, Goschzik T, Kool M, Northcott PA, von Hoff K, von Bueren AO, Friedrich C, Mynarek M, Skladny H, Fleischhack G, Taylor MD, Cremer F, Lichter P, Faldum A, Reifenberger G, Rutkowski S, Pfister SM.

Acta Neuropathol. 2014 Jul;128(1):137-49. doi: 10.1007/s00401-014-1276-0. Epub 2014 May 4.

PMID:
24791927
[PubMed - in process]
Free PMC Article
7.

Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas.

Yue D, Li H, Che J, Zhang Y, Tseng HH, Jin JQ, Luh TM, Giroux-Leprieur E, Mo M, Zheng Q, Shi H, Zhang H, Hao X, Wang C, Jablons DM, He B.

J Exp Clin Cancer Res. 2014 Apr 24;33:34. doi: 10.1186/1756-9966-33-34.

PMID:
24758269
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Molecular variants and mutations in medulloblastoma.

Schroeder K, Gururangan S.

Pharmgenomics Pers Med. 2014 Feb 4;7:43-51. doi: 10.2147/PGPM.S38698. eCollection 2014. Review.

PMID:
24523595
[PubMed]
Free PMC Article
9.

Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.

Cherry AL, Finta C, Karlström M, Jin Q, Schwend T, Astorga-Wells J, Zubarev RA, Del Campo M, Criswell AR, de Sanctis D, Jovine L, Toftgård R.

Acta Crystallogr D Biol Crystallogr. 2013 Dec;69(Pt 12):2563-79. doi: 10.1107/S0907444913028473. Epub 2013 Nov 19.

PMID:
24311597
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression.

Murphy BL, Obad S, Bihannic L, Ayrault O, Zindy F, Kauppinen S, Roussel MF.

Cancer Res. 2013 Dec 1;73(23):7068-78. doi: 10.1158/0008-5472.CAN-13-0927. Epub 2013 Oct 21.

PMID:
24145352
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Hedgehog/GLI signaling activates suppressor of cytokine signaling 1 (SOCS1) in epidermal and neural tumor cells.

Laner-Plamberger S, Wolff F, Kaser-Eichberger A, Swierczynski S, Hauser-Kronberger C, Frischauf AM, Eichberger T.

PLoS One. 2013 Sep 10;8(9):e75317. doi: 10.1371/journal.pone.0075317. eCollection 2013.

PMID:
24058673
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Integrated genotypic analysis of hedgehog-related genes identifies subgroups of keratocystic odontogenic tumor with distinct clinicopathological features.

Shimada Y, Katsube K, Kabasawa Y, Morita K, Omura K, Yamaguchi A, Sakamoto K.

PLoS One. 2013 Aug 7;8(8):e70995. doi: 10.1371/journal.pone.0070995. eCollection 2013.

PMID:
23951062
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Sonic Hedgehog promotes tumor cell survival by inhibiting CDON pro-apoptotic activity.

Delloye-Bourgeois C, Gibert B, Rama N, Delcros JG, Gadot N, Scoazec JY, Krauss R, Bernet A, Mehlen P.

PLoS Biol. 2013;11(8):e1001623. doi: 10.1371/journal.pbio.1001623. Epub 2013 Aug 6.

PMID:
23940460
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo.

Jalili A, Mertz KD, Romanov J, Wagner C, Kalthoff F, Stuetz A, Pathria G, Gschaider M, Stingl G, Wagner SN.

PLoS One. 2013 Jul 30;8(7):e69064. doi: 10.1371/journal.pone.0069064. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/ddd22094-5d8d-43ef-ad81-b95afe392ec7.

PMID:
23935925
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Arsenic trioxide prevents osteosarcoma growth by inhibition of GLI transcription via DNA damage accumulation.

Nakamura S, Nagano S, Nagao H, Ishidou Y, Yokouchi M, Abematsu M, Yamamoto T, Komiya S, Setoguchi T.

PLoS One. 2013 Jul 8;8(7):e69466. doi: 10.1371/journal.pone.0069466. Print 2013.

PMID:
23861973
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Signaling pathway and molecular subgroups of medulloblastoma.

Li KK, Lau KM, Ng HK.

Int J Clin Exp Pathol. 2013 Jun 15;6(7):1211-22. Print 2013. Review.

PMID:
23826403
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma.

Lim CB, Prêle CM, Cheah HM, Cheng YY, Klebe S, Reid G, Watkins DN, Baltic S, Thompson PJ, Mutsaers SE.

PLoS One. 2013 Jun 24;8(6):e66685. doi: 10.1371/journal.pone.0066685. Print 2013.

PMID:
23826113
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Hedgehog signaling pathway and ovarian cancer.

Chen Q, Gao G, Luo S.

Chin J Cancer Res. 2013 Jun;25(3):346-53. doi: 10.3978/j.issn.1000-9604.2013.06.04.

PMID:
23825912
[PubMed]
Free PMC Article
19.

Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.

Chari NS, Romano RA, Koster MI, Jaks V, Roop D, Flores ER, Teglund S, Sinha S, Gruber W, Aberger F, Medeiros LJ, Toftgard R, McDonnell TJ.

Cell Death Differ. 2013 Aug;20(8):1080-8. doi: 10.1038/cdd.2013.41. Epub 2013 May 17.

PMID:
23686138
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The dawn of hedgehog inhibitors: Vismodegib.

Sandhiya S, Melvin G, Kumar SS, Dkhar SA.

J Pharmacol Pharmacother. 2013 Jan;4(1):4-7. doi: 10.4103/0976-500X.107628.

PMID:
23662017
[PubMed]
Free PMC Article

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