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Results: 13

1.

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine.

Chappell WH, Abrams SL, Franklin RA, LaHair MM, Montalto G, Cervello M, Martelli AM, Nicoletti F, Candido S, Libra M, Polesel J, Talamini R, Milella M, Tafuri A, Steelman LS, McCubrey JA.

Cell Cycle. 2012 Dec 1;11(23):4447-61. doi: 10.4161/cc.22786. Epub 2012 Nov 16.

PMID:
23159854
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Identification and functional studies of a new Nrf2 partner IQGAP1: a critical role in the stability and transactivation of Nrf2.

Kim JH, Xu EY, Sacks DB, Lee J, Shu L, Xia B, Kong AN.

Antioxid Redox Signal. 2013 Jul 10;19(2):89-101. doi: 10.1089/ars.2012.4586. Epub 2012 Sep 17.

PMID:
22793650
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Heme-induced ROS in Trypanosoma cruzi activates CaMKII-like that triggers epimastigote proliferation. One helpful effect of ROS.

Nogueira NP, de Souza CF, Saraiva FM, Sultano PE, Dalmau SR, Bruno RE, Gonçalves Rde L, Laranja GA, Leal LH, Coelho MG, Masuda CA, Oliveira MF, Paes MC.

PLoS One. 2011;6(10):e25935. doi: 10.1371/journal.pone.0025935. Epub 2011 Oct 11.

PMID:
22022475
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Physical association of PDK1 with AKT1 is sufficient for pathway activation independent of membrane localization and phosphatidylinositol 3 kinase.

Ding Z, Liang J, Li J, Lu Y, Ariyaratna V, Lu Z, Davies MA, Westwick JK, Mills GB.

PLoS One. 2010 Mar 26;5(3):e9910. doi: 10.1371/journal.pone.0009910.

PMID:
20361045
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Rottlerin inhibits ROS formation and prevents NFkappaB activation in MCF-7 and HT-29 cells.

Maioli E, Greci L, Soucek K, Hyzdalova M, Pecorelli A, Fortino V, Valacchi G.

J Biomed Biotechnol. 2009;2009:742936. doi: 10.1155/2009/742936. Epub 2010 Feb 3.

PMID:
20168983
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Targeting signal transduction pathways to eliminate chemotherapeutic drug resistance and cancer stem cells.

McCubrey JA, Abrams SL, Stadelman K, Chappell WH, Lahair M, Ferland RA, Steelman LS.

Adv Enzyme Regul. 2010;50(1):285-307. doi: 10.1016/j.advenzreg.2009.10.016. Epub 2009 Nov 4. Review. No abstract available.

PMID:
19895837
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A novel role for calcium/calmodulin kinase II within the brainstem pedunculopontine tegmentum for the regulation of wakefulness and rapid eye movement sleep.

Stack EC, Desarnaud F, Siwek DF, Datta S.

J Neurochem. 2010 Jan;112(1):271-81. doi: 10.1111/j.1471-4159.2009.06452.x. Epub 2009 Oct 26.

PMID:
19860859
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Calcium/calmodulin-dependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages.

Zhang X, Wheeler D, Tang Y, Guo L, Shapiro RA, Ribar TJ, Means AR, Billiar TR, Angus DC, Rosengart MR.

J Immunol. 2008 Oct 1;181(7):5015-23.

PMID:
18802105
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.

McCubrey JA, Sokolosky ML, Lehmann BD, Taylor JR, Navolanic PM, Chappell WH, Abrams SL, Stadelman KM, Wong EW, Misaghian N, Horn S, Bäsecke J, Libra M, Stivala F, Ligresti G, Tafuri A, Milella M, Zarzycki M, Dzugaj A, Chiarini F, Evangelisti C, Martelli AM, Terrian DM, Franklin RA, Steelman LS.

Adv Enzyme Regul. 2008;48:113-35. doi: 10.1016/j.advenzreg.2008.02.006. Epub 2008 Feb 21. No abstract available.

PMID:
18423407
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Thioredoxin reductase is essential for thiol/disulfide redox control and oxidative stress survival of the anaerobe Bacteroides fragilis.

Rocha ER, Tzianabos AO, Smith CJ.

J Bacteriol. 2007 Nov;189(22):8015-23. Epub 2007 Sep 14.

PMID:
17873045
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Targeting the RAF/MEK/ERK, PI3K/AKT and p53 pathways in hematopoietic drug resistance.

McCubrey JA, Steelman LS, Franklin RA, Abrams SL, Chappell WH, Wong EW, Lehmann BD, Terrian DM, Basecke J, Stivala F, Libra M, Evangelisti C, Martelli AM.

Adv Enzyme Regul. 2007;47:64-103. Epub 2007 Mar 26. No abstract available.

PMID:
17382374
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The role of intracellular Ca2+ in the regulation of proteinase-activated receptor-2 mediated nuclear factor kappa B signalling in keratinocytes.

Macfarlane SR, Sloss CM, Cameron P, Kanke T, McKenzie RC, Plevin R.

Br J Pharmacol. 2005 Jun;145(4):535-44.

PMID:
15821758
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Ceramide alters endothelial cell permeability by a nonapoptotic mechanism.

Lindner K, Uhlig U, Uhlig S.

Br J Pharmacol. 2005 May;145(1):132-40.

PMID:
15735657
[PubMed - indexed for MEDLINE]
Free PMC Article

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