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DNA Immunization for HIV Vaccine Development.

Chen Y, Wang S, Lu S.

Vaccines (Basel). 2014 Feb 25;2(1):138-59. doi: 10.3390/vaccines2010138. Review.


Comparative Analysis of the Glycosylation Profiles of Membrane-Anchored HIV-1 Envelope Glycoprotein Trimers and Soluble gp140.

Go EP, Herschhorn A, Gu C, Castillo-Menendez L, Zhang S, Mao Y, Chen H, Ding H, Wakefield JK, Hua D, Liao HX, Kappes JC, Sodroski J, Desaire H.

J Virol. 2015 Aug;89(16):8245-57. doi: 10.1128/JVI.00628-15. Epub 2015 May 27.


Immunogenic Display of Purified Chemically Cross-Linked HIV-1 Spikes.

Leaman DP, Lee JH, Ward AB, Zwick MB.

J Virol. 2015 Jul;89(13):6725-45. doi: 10.1128/JVI.03738-14. Epub 2015 Apr 15.


Characterization of the enterovirus 71 P1 polyprotein expressed in Pichia pastor as a candidate vaccine.

Han X, Ying XL, Zhou SL, Han T, Huang H, Jin Q, Yang F, Sun QY, Sun XX.

Hum Vaccin Immunother. 2014;10(8):2220-6. doi: 10.4161/hv.29123.


RRE-dependent HIV-1 Env RNA effects on Gag protein expression, assembly and release.

López CS, Sloan R, Cylinder I, Kozak SL, Kabat D, Barklis E.

Virology. 2014 Aug;462-463:126-34. doi: 10.1016/j.virol.2014.05.019. Epub 2014 Jun 25.


Comparative immunogenicity of HIV-1 gp160, gp140 and gp120 expressed by live attenuated newcastle disease virus vector.

Khattar SK, Samal S, LaBranche CC, Montefiori DC, Collins PL, Samal SK.

PLoS One. 2013 Oct 1;8(10):e78521. doi: 10.1371/journal.pone.0078521. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/670112f8-b4fd-4622-8a8c-203dc647f807.


Robust neutralizing antibodies elicited by HIV-1 JRFL envelope glycoprotein trimers in nonhuman primates.

Chakrabarti BK, Feng Y, Sharma SK, McKee K, Karlsson Hedestam GB, Labranche CC, Montefiori DC, Mascola JR, Wyatt RT.

J Virol. 2013 Dec;87(24):13239-51. doi: 10.1128/JVI.01247-13. Epub 2013 Sep 25. Erratum in: J Virol. 2015 Jan;89(1):887.


Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.

Fouda GG, Amos JD, Wilks AB, Pollara J, Ray CA, Chand A, Kunz EL, Liebl BE, Whitaker K, Carville A, Smith S, Colvin L, Pickup DJ, Staats HF, Overman G, Eutsey-Lloyd K, Parks R, Chen H, Labranche C, Barnett S, Tomaras GD, Ferrari G, Montefiori DC, Liao HX, Letvin NL, Haynes BF, Permar SR.

J Virol. 2013 Jun;87(12):6986-99. doi: 10.1128/JVI.00528-13. Epub 2013 Apr 17.


Neutralizing antibodies to HIV-1 induced by immunization.

McCoy LE, Weiss RA.

J Exp Med. 2013 Feb 11;210(2):209-23. doi: 10.1084/jem.20121827. Review.


Recombinant HIV envelope proteins fail to engage germline versions of anti-CD4bs bNAbs.

Hoot S, McGuire AT, Cohen KW, Strong RK, Hangartner L, Klein F, Diskin R, Scheid JF, Sather DN, Burton DR, Stamatatos L.

PLoS Pathog. 2013 Jan;9(1):e1003106. doi: 10.1371/journal.ppat.1003106. Epub 2013 Jan 3. Erratum in: PLoS Pathog. 2013 Jul;9(9). doi:10.1371/annotation/ed7c0148-97eb-4416-824d-6e6d1aaeceef.


Gene-based vaccination with a mismatched envelope protects against simian immunodeficiency virus infection in nonhuman primates.

Flatz L, Cheng C, Wang L, Foulds KE, Ko SY, Kong WP, Roychoudhuri R, Shi W, Bao S, Todd JP, Asmal M, Shen L, Donaldson M, Schmidt SD, Gall JG, Pinschewer DD, Letvin NL, Rao S, Mascola JR, Roederer M, Nabel GJ.

J Virol. 2012 Aug;86(15):7760-70. doi: 10.1128/JVI.00599-12. Epub 2012 May 16.


Broad HIV-1 neutralizing antibody response induced by heterologous gp140/gp145 DNA prime-vaccinia boost immunization.

Liu L, Hao Y, Luo Z, Huang Y, Hu X, Liu Y, Shao Y.

Vaccine. 2012 Jun 13;30(28):4135-43. doi: 10.1016/j.vaccine.2012.04.075. Epub 2012 May 2.


Envelope variable region 4 is the first target of neutralizing antibodies in early simian immunodeficiency virus mac251 infection of rhesus monkeys.

Yeh WW, Brassard LM, Miller CA, Basavapathruni A, Zhang J, Rao SS, Nabel GJ, Mascola JR, Letvin NL, Seaman MS.

J Virol. 2012 Jul;86(13):7052-9. doi: 10.1128/JVI.00107-12. Epub 2012 Apr 24.


Rational design of vaccines to elicit broadly neutralizing antibodies to HIV-1.

Kwong PD, Mascola JR, Nabel GJ.

Cold Spring Harb Perspect Med. 2011 Sep;1(1):a007278. doi: 10.1101/cshperspect.a007278. Review.


Engineering, expression, purification, and characterization of stable clade A/B recombinant soluble heterotrimeric gp140 proteins.

Sellhorn G, Kraft Z, Caldwell Z, Ellingson K, Mineart C, Seaman MS, Montefiori DC, Lagerquist E, Stamatatos L.

J Virol. 2012 Jan;86(1):128-42. doi: 10.1128/JVI.06363-11. Epub 2011 Oct 26.


Characterization of glycosylation profiles of HIV-1 transmitted/founder envelopes by mass spectrometry.

Go EP, Hewawasam G, Liao HX, Chen H, Ping LH, Anderson JA, Hua DC, Haynes BF, Desaire H.

J Virol. 2011 Aug;85(16):8270-84. doi: 10.1128/JVI.05053-11. Epub 2011 Jun 8.


Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines.

Flatz L, Roychoudhuri R, Honda M, Filali-Mouhim A, Goulet JP, Kettaf N, Lin M, Roederer M, Haddad EK, Sékaly RP, Nabel GJ.

Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5724-9. doi: 10.1073/pnas.1013084108. Epub 2011 Mar 21.


HIV type 1 Env precursor cleavage state affects recognition by both neutralizing and nonneutralizing gp41 antibodies.

Chakrabarti BK, Pancera M, Phogat S, O'Dell S, McKee K, Guenaga J, Robinson J, Mascola J, Wyatt RT.

AIDS Res Hum Retroviruses. 2011 Aug;27(8):877-87. doi: 10.1089/AID.2010.0281. Epub 2011 Jan 19.


Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity.

Kong L, Sheppard NC, Stewart-Jones GB, Robson CL, Chen H, Xu X, Krashias G, Bonomelli C, Scanlan CN, Kwong PD, Jeffs SA, Jones IM, Sattentau QJ.

J Mol Biol. 2010 Oct 15;403(1):131-47. doi: 10.1016/j.jmb.2010.08.033. Epub 2010 Aug 25.


Purification and characterization of HIV-human protein complexes.

Jäger S, Gulbahce N, Cimermancic P, Kane J, He N, Chou S, D'Orso I, Fernandes J, Jang G, Frankel AD, Alber T, Zhou Q, Krogan NJ.

Methods. 2011 Jan;53(1):13-9. doi: 10.1016/j.ymeth.2010.08.007. Epub 2010 Aug 12. Review.

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