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Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.

Lee CS, Dagnino-Acosta A, Yarotskyy V, Hanna A, Lyfenko A, Knoblauch M, Georgiou DK, Poché RA, Swank MW, Long C, Ismailov II, Lanner J, Tran T, Dong K, Rodney GG, Dickinson ME, Beeton C, Zhang P, Dirksen RT, Hamilton SL.

Skelet Muscle. 2015 Jan 29;5:4. doi: 10.1186/s13395-014-0027-1. eCollection 2015.


Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death.

Qi Y, Wang J, Bomben VC, Li DP, Chen SR, Sun H, Xi Y, Reed JG, Cheng J, Pan HL, Noebels JL, Yeh ET.

Neuron. 2014 Sep 3;83(5):1159-71. doi: 10.1016/j.neuron.2014.07.042.


Targeting of GFP-Cre to the mouse Cyp11a1 locus both drives cre recombinase expression in steroidogenic cells and permits generation of Cyp11a1 knock out mice.

O'Hara L, York JP, Zhang P, Smith LB.

PLoS One. 2014 Jan 3;9(1):e84541. doi: 10.1371/journal.pone.0084541. eCollection 2014.


S151A δ-sarcoglycan mutation causes a mild phenotype of cardiomyopathy in mice.

Rutschow D, Bauer R, Göhringer C, Bekeredjian R, Schinkel S, Straub V, Koenen M, Weichenhan D, Katus HA, Müller OJ.

Eur J Hum Genet. 2014 Jan;22(1):119-25. doi: 10.1038/ejhg.2013.97. Epub 2013 May 22.


Utx is required for proper induction of ectoderm and mesoderm during differentiation of embryonic stem cells.

Morales Torres C, Laugesen A, Helin K.

PLoS One. 2013;8(4):e60020. doi: 10.1371/journal.pone.0060020. Epub 2013 Apr 3.


Expression of wild-type Rp1 protein in Rp1 knock-in mice rescues the retinal degeneration phenotype.

Liu Q, Collin RW, Cremers FP, den Hollander AI, van den Born LI, Pierce EA.

PLoS One. 2012;7(8):e43251. doi: 10.1371/journal.pone.0043251. Epub 2012 Aug 21.


Production of a mouse line with a conditional Crim1 mutant allele.

Chiu HS, York JP, Wilkinson L, Zhang P, Little MH, Pennisi DJ.

Genesis. 2012 Sep;50(9):711-6. doi: 10.1002/dvg.22032. Epub 2012 May 19.


Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis.

Mikolcevic P, Sigl R, Rauch V, Hess MW, Pfaller K, Barisic M, Pelliniemi LJ, Boesl M, Geley S.

Mol Cell Biol. 2012 Feb;32(4):868-79. doi: 10.1128/MCB.06261-11. Epub 2011 Dec 19.


Vectors for ligation-independent construction of lacZ gene fusions and cloning of PCR products using a nicking endonuclease.

Oster CJ, Phillips GJ.

Plasmid. 2011 Sep;66(3):180-5. doi: 10.1016/j.plasmid.2011.07.007. Epub 2011 Aug 10.


Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting.

Nedelkova M, Maresca M, Fu J, Rostovskaya M, Chenna R, Thiede C, Anastassiadis K, Sarov M, Stewart AF.

Nucleic Acids Res. 2011 Nov 1;39(20):e137. doi: 10.1093/nar/gkr668. Epub 2011 Aug 18.


Mice lacking the USP2 deubiquitinating enzyme have severe male subfertility associated with defects in fertilization and sperm motility.

Bedard N, Yang Y, Gregory M, Cyr DG, Suzuki J, Yu X, Chian RC, Hermo L, O'Flaherty C, Smith CE, Clarke HJ, Wing SS.

Biol Reprod. 2011 Sep;85(3):594-604. doi: 10.1095/biolreprod.110.088542. Epub 2011 May 4.


A mouse M-opsin monochromat: retinal cone photoreceptors have increased M-opsin expression when S-opsin is knocked out.

Daniele LL, Insinna C, Chance R, Wang J, Nikonov SS, Pugh EN Jr.

Vision Res. 2011 Feb 23;51(4):447-58. doi: 10.1016/j.visres.2010.12.017. Epub 2011 Jan 8.


The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice.

Gao X, Shin YH, Li M, Wang F, Tong Q, Zhang P.

PLoS One. 2010 Nov 16;5(11):e14005. doi: 10.1371/journal.pone.0014005.


Isolation of specific clones from nonarrayed BAC libraries through homologous recombination.

Nefedov M, Carbone L, Field M, Schein J, de Jong PJ.

J Biomed Biotechnol. 2011;2011:560124. doi: 10.1155/2011/560124. Epub 2010 Oct 13.


Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.

Graziotto JJ, Farkas MH, Bujakowska K, Deramaudt BM, Zhang Q, Nandrot EF, Inglehearn CF, Bhattacharya SS, Pierce EA.

Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):190-8. doi: 10.1167/iovs.10-5194. Print 2011 Jan.


FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a.

Urness LD, Paxton CN, Wang X, Schoenwolf GC, Mansour SL.

Dev Biol. 2010 Apr 15;340(2):595-604. doi: 10.1016/j.ydbio.2010.02.016. Epub 2010 Feb 18.


Calmodulin kinase II-mediated sarcoplasmic reticulum Ca2+ leak promotes atrial fibrillation in mice.

Chelu MG, Sarma S, Sood S, Wang S, van Oort RJ, Skapura DG, Li N, Santonastasi M, Müller FU, Schmitz W, Schotten U, Anderson ME, Valderrábano M, Dobrev D, Wehrens XH.

J Clin Invest. 2009 Jul;119(7):1940-51.


Loss of spindle assembly checkpoint-mediated inhibition of Cdc20 promotes tumorigenesis in mice.

Li M, Fang X, Wei Z, York JP, Zhang P.

J Cell Biol. 2009 Jun 15;185(6):983-94. doi: 10.1083/jcb.200904020. Erratum in: J Cell Biol. 2009 Jul 13;186(1):161.


Construction of gene-targeting vectors by recombineering.

Lee SC, Wang W, Liu P.

Methods Mol Biol. 2009;530:15-27. doi: 10.1007/978-1-59745-471-1_2.


Mutability and importance of a hypermutable cell subpopulation that produces stress-induced mutants in Escherichia coli.

Gonzalez C, Hadany L, Ponder RG, Price M, Hastings PJ, Rosenberg SM.

PLoS Genet. 2008 Oct 3;4(10):e1000208. doi: 10.1371/journal.pgen.1000208.

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