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Items: 1 to 20 of 179


Single-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRP.

Suhl JA, Warren ST.

J Exp Neurosci. 2015 Dec 8;9(Suppl 2):35-41. doi: 10.4137/JEN.S25524. eCollection 2015. Review.


New X-chromosomal interactors of dFMRP regulate axonal and synaptic morphology of brain neurons in Drosophila melanogaster.

Georgieva D, Dimitrov R, Kitanova M, Genova G.

Biotechnol Biotechnol Equip. 2014 Jul 4;28(4):697-709. Epub 2014 Oct 23.


Fmrp Interacts with Adar and Regulates RNA Editing, Synaptic Density and Locomotor Activity in Zebrafish.

Shamay-Ramot A, Khermesh K, Porath HT, Barak M, Pinto Y, Wachtel C, Zilberberg A, Lerer-Goldshtein T, Efroni S, Levanon EY, Appelbaum L.

PLoS Genet. 2015 Dec 4;11(12):e1005702. doi: 10.1371/journal.pgen.1005702. eCollection 2015 Dec.


Transmission, Development, and Plasticity of Synapses.

Harris KP, Littleton JT.

Genetics. 2015 Oct;201(2):345-75. doi: 10.1534/genetics.115.176529.


A novel link between FMR gene and the JNK pathway provides clues to possible role in malignant pleural mesothelioma.

Srivastava A.

FEBS Open Bio. 2015 Aug 19;5:705-11. doi: 10.1016/j.fob.2015.07.005. eCollection 2015.


Tricornered Kinase Regulates Synapse Development by Regulating the Levels of Wiskott-Aldrich Syndrome Protein.

Natarajan R, Barber K, Buckley A, Cho P, Egbejimi A, Wairkar YP.

PLoS One. 2015 Sep 22;10(9):e0138188. doi: 10.1371/journal.pone.0138188. eCollection 2015.


In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.

Wang T, de Kok L, Willemsen R, Elgersma Y, Borst JG.

Front Cell Neurosci. 2015 Jul 3;9:234. doi: 10.3389/fncel.2015.00234. eCollection 2015.


Drosophila Cbp53E Regulates Axon Growth at the Neuromuscular Junction.

Hagel KR, Beriont J, Tessier CR.

PLoS One. 2015 Jul 13;10(7):e0132636. doi: 10.1371/journal.pone.0132636. eCollection 2015.


The translational regulator Cup controls NMJ presynaptic terminal morphology.

Menon KP, Carrillo RA, Zinn K.

Mol Cell Neurosci. 2015 Jul;67:126-36. doi: 10.1016/j.mcn.2015.06.010. Epub 2015 Jun 20.


On the Teneurin track: a new synaptic organization molecule emerges.

Mosca TJ.

Front Cell Neurosci. 2015 May 27;9:204. doi: 10.3389/fncel.2015.00204. eCollection 2015. Review.


Dysregulated Dscam levels act through Abelson tyrosine kinase to enlarge presynaptic arbors.

Sterne GR, Kim JH, Ye B.

Elife. 2015 May 19;4. doi: 10.7554/eLife.05196.


Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back.

Gross C, Hoffmann A, Bassell GJ, Berry-Kravis EM.

Neurotherapeutics. 2015 Jul;12(3):584-608. doi: 10.1007/s13311-015-0355-9.


The Drosophila ortholog of the Zc3h14 RNA binding protein acts within neurons to pattern axon projection in the developing brain.

Kelly SM, Bienkowski R, Banerjee A, Melicharek DJ, Brewer ZA, Marenda DR, Corbett AH, Moberg KH.

Dev Neurobiol. 2016 Jan;76(1):93-106. doi: 10.1002/dneu.22301. Epub 2015 Jun 1.


Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.

Gross C, Chang CW, Kelly SM, Bhattacharya A, McBride SM, Danielson SW, Jiang MQ, Chan CB, Ye K, Gibson JR, Klann E, Jongens TA, Moberg KH, Huber KM, Bassell GJ.

Cell Rep. 2015 May 5;11(5):727-36. doi: 10.1016/j.celrep.2015.03.060. Epub 2015 Apr 23.


Activity-dependent FMRP requirements in development of the neural circuitry of learning and memory.

Doll CA, Broadie K.

Development. 2015 Apr 1;142(7):1346-56. doi: 10.1242/dev.117127.


Fragile X mental retardation protein: A paradigm for translational control by RNA-binding proteins.

Chen E, Joseph S.

Biochimie. 2015 Jul;114:147-54. doi: 10.1016/j.biochi.2015.02.005. Epub 2015 Feb 17. Review.


A novel fragile X syndrome mutation reveals a conserved role for the carboxy-terminus in FMRP localization and function.

Okray Z, de Esch CE, Van Esch H, Devriendt K, Claeys A, Yan J, Verbeeck J, Froyen G, Willemsen R, de Vrij FM, Hassan BA.

EMBO Mol Med. 2015 Feb 17;7(4):423-37. doi: 10.15252/emmm.201404576.


BMP signaling and microtubule organization regulate synaptic strength.

Ball RW, Peled ES, Guerrero G, Isacoff EY.

Neuroscience. 2015 Apr 16;291:155-66. doi: 10.1016/j.neuroscience.2015.01.069. Epub 2015 Feb 11.


Epigenetic regulation of neuronal dendrite and dendritic spine development.

Smrt RD, Zhao X.

Front Biol (Beijing). 2010 Aug;5(4):304-323.


PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome.

Choi CH, Schoenfeld BP, Weisz ED, Bell AJ, Chambers DB, Hinchey J, Choi RJ, Hinchey P, Kollaros M, Gertner MJ, Ferrick NJ, Terlizzi AM, Yohn N, Koenigsberg E, Liebelt DA, Zukin RS, Woo NH, Tranfaglia MR, Louneva N, Arnold SE, Siegel SJ, Bolduc FV, McDonald TV, Jongens TA, McBride SM.

J Neurosci. 2015 Jan 7;35(1):396-408. doi: 10.1523/JNEUROSCI.1356-12.2015.

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