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Items: 1 to 20 of 33


Fanconi anemia gene editing by the CRISPR/Cas9 system.

Osborn MJ, Gabriel R, Webber BR, DeFeo AP, McElroy AN, Jarjour J, Starker CG, Wagner JE, Joung JK, Voytas DF, von Kalle C, Schmidt M, Blazar BR, Tolar J.

Hum Gene Ther. 2015 Feb;26(2):114-26. doi: 10.1089/hum.2014.111.


Potential application of curcumin and its analogues in the treatment strategy of patients with primary epithelial ovarian cancer.

Terlikowska KM, Witkowska AM, Zujko ME, Dobrzycka B, Terlikowski SJ.

Int J Mol Sci. 2014 Nov 25;15(12):21703-22. doi: 10.3390/ijms151221703. Review.


Large deletion causing von Hippel-Lindau disease and hereditary breast cancer syndrome.

Krzystolik K, Jakubowska A, Gronwald J, Krawczyński MR, Drobek-Słowik M, Sagan L, Cyryłowski L, Lubiński W, Lubiński J, Cybulski C.

Hered Cancer Clin Pract. 2014 Jun 18;12(1):16. doi: 10.1186/1897-4287-12-16. eCollection 2014.


Identification and validation of an anthracycline/cyclophosphamide-based chemotherapy response assay in breast cancer.

Mulligan JM, Hill LA, Deharo S, Irwin G, Boyle D, Keating KE, Raji OY, McDyer FA, O'Brien E, Bylesjo M, Quinn JE, Lindor NM, Mullan PB, James CR, Walker SM, Kerr P, James J, Davison TS, Proutski V, Salto-Tellez M, Johnston PG, Couch FJ, Paul Harkin D, Kennedy RD.

J Natl Cancer Inst. 2014 Jan;106(1):djt335. doi: 10.1093/jnci/djt335.


Fanconi anemia signaling network regulates the spindle assembly checkpoint.

Nalepa G, Enzor R, Sun Z, Marchal C, Park SJ, Yang Y, Tedeschi L, Kelich S, Hanenberg H, Clapp DW.

J Clin Invest. 2013 Sep;123(9):3839-47. doi: 10.1172/JCI67364. Epub 2013 Aug 15.


Human single-stranded DNA binding proteins are essential for maintaining genomic stability.

Ashton NW, Bolderson E, Cubeddu L, O'Byrne KJ, Richard DJ.

BMC Mol Biol. 2013 Apr 1;14:9. doi: 10.1186/1471-2199-14-9. Review.


A case report of Fanconi anemia diagnosed by genetic testing followed by prenatal diagnosis.

Lee HJ, Park S, Kang HJ, Jun JK, Lee JA, Lee DS, Park SS, Seong MW.

Ann Lab Med. 2012 Sep;32(5):380-4. doi: 10.3343/alm.2012.32.5.380. Epub 2012 Aug 13.


Human KIAA1018/FAN1 nuclease is a new mitotic substrate of APC/C(Cdh1).

Lai F, Hu K, Wu Y, Tang J, Sang Y, Cao J, Kang T.

Chin J Cancer. 2012 Sep;31(9):440-8. doi: 10.5732/cjc.012.10144. Epub 2012 Aug 2.


The Fanconi anemia pathway in replication stress and DNA crosslink repair.

Jones MJ, Huang TT.

Cell Mol Life Sci. 2012 Dec;69(23):3963-74. doi: 10.1007/s00018-012-1051-0. Epub 2012 Jun 29. Review.


Mechanism of cell death resulting from DNA interstrand cross-linking in mammalian cells.

Osawa T, Davies D, Hartley JA.

Cell Death Dis. 2011 Aug 4;2:e187. doi: 10.1038/cddis.2011.70.


Formation of cyclophosphamide specific DNA adducts in hematological diseases.

Johnson LA, Malayappan B, Tretyakova N, Campbell C, MacMillan ML, Wagner JE, Jacobson PA.

Pediatr Blood Cancer. 2012 May;58(5):708-14. doi: 10.1002/pbc.23254. Epub 2011 Jul 25.


Targeting and processing of site-specific DNA interstrand crosslinks.

Vasquez KM.

Environ Mol Mutagen. 2010 Jul;51(6):527-39. doi: 10.1002/em.20557. Review.


Fanconi anemia proteins and endogenous stresses.

Pang Q, Andreassen PR.

Mutat Res. 2009 Jul 31;668(1-2):42-53.


Checkpoint signaling from a single DNA interstrand crosslink.

Ben-Yehoyada M, Wang LC, Kozekov ID, Rizzo CJ, Gottesman ME, Gautier J.

Mol Cell. 2009 Sep 11;35(5):704-15. doi: 10.1016/j.molcel.2009.08.014.


Repair of laser-localized DNA interstrand cross-links in G1 phase mammalian cells.

Muniandy PA, Thapa D, Thazhathveetil AK, Liu ST, Seidman MM.

J Biol Chem. 2009 Oct 9;284(41):27908-17. doi: 10.1074/jbc.M109.029025. Epub 2009 Aug 14.


MRE11-RAD50-NBS1 is a critical regulator of FANCD2 stability and function during DNA double-strand break repair.

Roques C, Coulombe Y, Delannoy M, Vignard J, Grossi S, Brodeur I, Rodrigue A, Gautier J, Stasiak AZ, Stasiak A, Constantinou A, Masson JY.

EMBO J. 2009 Aug 19;28(16):2400-13. doi: 10.1038/emboj.2009.193. Epub 2009 Jul 16.


The role of DNA damage repair in aging of adult stem cells.

Kenyon J, Gerson SL.

Nucleic Acids Res. 2007;35(22):7557-65. Epub 2007 Dec 26. Review.


DNA structure-induced recruitment and activation of the Fanconi anemia pathway protein FANCD2.

Sobeck A, Stone S, Hoatlin ME.

Mol Cell Biol. 2007 Jun;27(12):4283-92. Epub 2007 Apr 9.


Defective mitochondrial peroxiredoxin-3 results in sensitivity to oxidative stress in Fanconi anemia.

Mukhopadhyay SS, Leung KS, Hicks MJ, Hastings PJ, Youssoufian H, Plon SE.

J Cell Biol. 2006 Oct 23;175(2):225-35.

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