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Items: 1 to 20 of 146


PSD-95 family MAGUKs are essential for anchoring AMPA and NMDA receptor complexes at the postsynaptic density.

Chen X, Levy JM, Hou A, Winters C, Azzam R, Sousa AA, Leapman RD, Nicoll RA, Reese TS.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6983-92. doi: 10.1073/pnas.1517045112. Epub 2015 Nov 24.


Abnormalities in synaptic dynamics during development in a mouse model of spinocerebellar ataxia type 1.

Hatanaka Y, Watase K, Wada K, Nagai Y.

Sci Rep. 2015 Nov 4;5:16102. doi: 10.1038/srep16102.


PKA Inhibitor H89 (N-[2-p-bromocinnamylamino-ethyl]-5-isoquinolinesulfonamide) Attenuates Synaptic Dysfunction and Neuronal Cell Death following Ischemic Injury.

Song J, Cheon SY, Lee WT, Park KA, Lee JE.

Neural Plast. 2015;2015:374520. doi: 10.1155/2015/374520. Epub 2015 Sep 13.


Altered NMDA receptor function in primary cultures of hippocampal neurons from mice lacking the Homer2 gene.

Smothers CT, Szumlinski KK, Worley PF, Woodward JJ.

Synapse. 2016 Jan;70(1):33-9. doi: 10.1002/syn.21869. Epub 2015 Oct 15.


Chronic Lead Exposure and Mixed Factors of Gender×Age×Brain Regions Interactions on Dendrite Growth, Spine Maturity and NDR Kinase.

Du Y, Ge MM, Xue W, Yang QQ, Wang S, Xu Y, Wang HL.

PLoS One. 2015 Sep 14;10(9):e0138112. doi: 10.1371/journal.pone.0138112. eCollection 2015.


Ultrastructural analyses in the hippocampus CA1 field in Shank3-deficient mice.

Uppal N, Puri R, Yuk F, Janssen WG, Bozdagi-Gunal O, Harony-Nicolas H, Dickstein DL, Buxbaum JD, Hof PR.

Mol Autism. 2015 Jun 30;6:41. doi: 10.1186/s13229-015-0036-x. eCollection 2015.


Autism-like Deficits in Shank3-Deficient Mice Are Rescued by Targeting Actin Regulators.

Duffney LJ, Zhong P, Wei J, Matas E, Cheng J, Qin L, Ma K, Dietz DM, Kajiwara Y, Buxbaum JD, Yan Z.

Cell Rep. 2015 Jun 9;11(9):1400-13. doi: 10.1016/j.celrep.2015.04.064. Epub 2015 May 28.


Phelan-McDermid Syndrome and SHANK3: Implications for Treatment.

Costales JL, Kolevzon A.

Neurotherapeutics. 2015 Jul;12(3):620-30. doi: 10.1007/s13311-015-0352-z.


miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement.

Gu QH, Yu D, Hu Z, Liu X, Yang Y, Luo Y, Zhu J, Li Z.

Nat Commun. 2015 Apr 10;6:6789. doi: 10.1038/ncomms7789.


Shank1 regulates excitatory synaptic transmission in mouse hippocampal parvalbumin-expressing inhibitory interneurons.

Mao W, Watanabe T, Cho S, Frost JL, Truong T, Zhao X, Futai K.

Eur J Neurosci. 2015 Apr;41(8):1025-35. doi: 10.1111/ejn.12877. Epub 2015 Mar 25.


Differential distribution of Shank and GKAP at the postsynaptic density.

Tao-Cheng JH, Yang Y, Reese TS, Dosemeci A.

PLoS One. 2015 Mar 16;10(3):e0118750. doi: 10.1371/journal.pone.0118750. eCollection 2015.


Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap.

Yang Y, Wei M, Xiong Y, Du X, Zhu S, Yang L, Zhang C, Liu JJ.

Cell Res. 2015 Apr;25(4):496-516. doi: 10.1038/cr.2015.31. Epub 2015 Mar 13.


Homer2 deletion alters dendritic spine morphology but not alcohol-associated adaptations in GluN2B-containing N-methyl-D-aspartate receptors in the nucleus accumbens.

McGuier NS, Padula AE, Mulholland PJ, Chandler LJ.

Front Pharmacol. 2015 Feb 23;6:28. doi: 10.3389/fphar.2015.00028. eCollection 2015.


Homer3 regulates the establishment of neutrophil polarity.

Wu J, Pipathsouk A, Keizer-Gunnink A, Fusetti F, Alkema W, Liu S, Altschuler S, Wu L, Kortholt A, Weiner OD.

Mol Biol Cell. 2015 May 1;26(9):1629-39. doi: 10.1091/mbc.E14-07-1197. Epub 2015 Mar 4.


FMRP interacts with G-quadruplex structures in the 3'-UTR of its dendritic target Shank1 mRNA.

Zhang Y, Gaetano CM, Williams KR, Bassell GJ, Mihailescu MR.

RNA Biol. 2014;11(11):1364-74. doi: 10.1080/15476286.2014.996464.


Reduced SNAP-25 increases PSD-95 mobility and impairs spine morphogenesis.

Fossati G, Morini R, Corradini I, Antonucci F, Trepte P, Edry E, Sharma V, Papale A, Pozzi D, Defilippi P, Meier JC, Brambilla R, Turco E, Rosenblum K, Wanker EE, Ziv NE, Menna E, Matteoli M.

Cell Death Differ. 2015 Sep;22(9):1425-36. doi: 10.1038/cdd.2014.227. Epub 2015 Feb 13.


Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear.

Braude JP, Vijayakumar S, Baumgarner K, Laurine R, Jones TA, Jones SM, Pyott SJ.

Hear Res. 2015 Mar;321:52-64. doi: 10.1016/j.heares.2015.01.008. Epub 2015 Jan 28.


Activation of InsP₃ receptors is sufficient for inducing graded intrinsic plasticity in rat hippocampal pyramidal neurons.

Ashhad S, Johnston D, Narayanan R.

J Neurophysiol. 2015 Apr 1;113(7):2002-13. doi: 10.1152/jn.00833.2014. Epub 2014 Dec 30.


SAP97-mediated ADAM10 trafficking from Golgi outposts depends on PKC phosphorylation.

Saraceno C, Marcello E, Di Marino D, Borroni B, Claeysen S, Perroy J, Padovani A, Tramontano A, Gardoni F, Di Luca M.

Cell Death Dis. 2014 Nov 27;5:e1547. doi: 10.1038/cddis.2014.492.


Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4.

Gomez AM, Froemke RC, Burden SJ.

Elife. 2014 Nov 19;3:e04287. doi: 10.7554/eLife.04287.

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