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Results: 1 to 20 of 21

1.

Targeted therapy in nonmelanoma skin cancers.

Spallone G, Botti E, Costanzo A.

Cancers (Basel). 2011 May 3;3(2):2255-73. doi: 10.3390/cancers3022255.

PMID:
24212808
[PubMed]
Free PMC Article
2.

Insulin-like growth factor 1 receptor as a therapeutic target in ewing sarcoma: lack of consistent upregulation or recurrent mutation and a review of the clinical trial literature.

O'Neill A, Shah N, Zitomersky N, Ladanyi M, Shukla N, Uren A, Loeb D, Toretsky J.

Sarcoma. 2013;2013:450478. doi: 10.1155/2013/450478. Epub 2013 Jan 28.

PMID:
23431249
[PubMed]
Free PMC Article
3.

Targeted therapy in Ewing sarcoma.

Lissat A, Chao MM, Kontny U.

ISRN Oncol. 2012;2012:609439. doi: 10.5402/2012/609439. Epub 2012 May 28.

PMID:
22690342
[PubMed]
Free PMC Article
4.

The insulin-like growth factor system in cancer.

Weroha SJ, Haluska P.

Endocrinol Metab Clin North Am. 2012 Jun;41(2):335-50, vi. doi: 10.1016/j.ecl.2012.04.014. Review.

PMID:
22682634
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Role of IGF-1 receptor in radiation response.

Valenciano A, Henríquez-Hernández LA, Moreno M, Lloret M, Lara PC.

Transl Oncol. 2012 Feb;5(1):1-9. Epub 2012 Feb 1.

PMID:
22348170
[PubMed]
Free PMC Article
6.

Treatment of Bone Tumors.

Rajani R, Gibbs CP.

Surg Pathol Clin. 2012 Mar 1;5(1):301-318.

PMID:
22328909
[PubMed]
Free PMC Article
7.

Phase I/II trial and pharmacokinetic study of cixutumumab in pediatric patients with refractory solid tumors and Ewing sarcoma: a report from the Children's Oncology Group.

Malempati S, Weigel B, Ingle AM, Ahern CH, Carroll JM, Roberts CT, Reid JM, Schmechel S, Voss SD, Cho SY, Chen HX, Krailo MD, Adamson PC, Blaney SM.

J Clin Oncol. 2012 Jan 20;30(3):256-62. doi: 10.1200/JCO.2011.37.4355. Epub 2011 Dec 19.

PMID:
22184397
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Predicting IGF-1R therapy response in bone sarcomas: immuno-SPECT imaging with radiolabeled R1507.

Fleuren ED, Versleijen-Jonkers YM, van de Luijtgaarden AC, Molkenboer-Kuenen JD, Heskamp S, Roeffen MH, van Laarhoven HW, Houghton PJ, Oyen WJ, Boerman OC, van der Graaf WT.

Clin Cancer Res. 2011 Dec 15;17(24):7693-703. doi: 10.1158/1078-0432.CCR-11-1488. Epub 2011 Oct 28.

PMID:
22038993
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study.

Pappo AS, Patel SR, Crowley J, Reinke DK, Kuenkele KP, Chawla SP, Toner GC, Maki RG, Meyers PA, Chugh R, Ganjoo KN, Schuetze SM, Juergens H, Leahy MG, Geoerger B, Benjamin RS, Helman LJ, Baker LH.

J Clin Oncol. 2011 Dec 1;29(34):4541-7. doi: 10.1200/JCO.2010.34.0000. Epub 2011 Oct 24.

PMID:
22025149
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Optimally discriminative subnetwork markers predict response to chemotherapy.

Dao P, Wang K, Collins C, Ester M, Lapuk A, Sahinalp SC.

Bioinformatics. 2011 Jul 1;27(13):i205-13. doi: 10.1093/bioinformatics/btr245.

PMID:
21685072
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Targeting the Insulin-Like Growth Factor 1 Receptor in Ewing's Sarcoma: Reality and Expectations.

Olmos D, Martins AS, Jones RL, Alam S, Scurr M, Judson IR.

Sarcoma. 2011;2011:402508. doi: 10.1155/2011/402508. Epub 2011 May 3.

PMID:
21647361
[PubMed]
Free PMC Article
12.

The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs).

Pantaleo MA, Astolfi A, Nannini M, Biasco G.

J Transl Med. 2010 Nov 15;8:117. doi: 10.1186/1479-5876-8-117.

PMID:
21078151
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Dual inhibition of epidermal growth factor receptor and insulin-like growth factor receptor I: reduction of angiogenesis and tumor growth in cutaneous squamous cell carcinoma.

Galer CE, Corey CL, Wang Z, Younes MN, Gomez-Rivera F, Jasser SA, Ludwig DL, El-Naggar AK, Weber RS, Myers JN.

Head Neck. 2011 Feb;33(2):189-98. doi: 10.1002/hed.21419.

PMID:
20848439
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study.

Molife LR, Fong PC, Paccagnella L, Reid AH, Shaw HM, Vidal L, Arkenau HT, Karavasilis V, Yap TA, Olmos D, Spicer J, Postel-Vinay S, Yin D, Lipton A, Demers L, Leitzel K, Gualberto A, de Bono JS.

Br J Cancer. 2010 Jul 27;103(3):332-9. doi: 10.1038/sj.bjc.6605767. Epub 2010 Jul 13.

PMID:
20628389
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Recent advances in the molecular pathogenesis of Ewing's sarcoma.

Toomey EC, Schiffman JD, Lessnick SL.

Oncogene. 2010 Aug 12;29(32):4504-16. doi: 10.1038/onc.2010.205. Epub 2010 Jun 14. Review.

PMID:
20543858
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Sequencing of type I insulin-like growth factor receptor inhibition affects chemotherapy response in vitro and in vivo.

Zeng X, Sachdev D, Zhang H, Gaillard-Kelly M, Yee D.

Clin Cancer Res. 2009 Apr 15;15(8):2840-9. doi: 10.1158/1078-0432.CCR-08-1401. Epub 2009 Apr 7.

PMID:
19351773
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

IGF-1 receptor inhibitors in clinical trials--early lessons.

Weroha SJ, Haluska P.

J Mammary Gland Biol Neoplasia. 2008 Dec;13(4):471-83. doi: 10.1007/s10911-008-9104-6. Epub 2008 Nov 21. Review.

PMID:
19023648
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Pediatric developmental therapies: interesting new drugs now in early-stage clinical trials.

Macy ME, Sawczyn KK, Garrington TP, Graham DK, Gore L.

Curr Oncol Rep. 2008 Nov;10(6):477-90. Review.

PMID:
18928662
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: lessons from the first clinical trials.

Rodon J, DeSantos V, Ferry RJ Jr, Kurzrock R.

Mol Cancer Ther. 2008 Sep;7(9):2575-88. doi: 10.1158/1535-7163.MCT-08-0265. Review.

PMID:
18790742
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

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