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Items: 1 to 20 of 32


Structure, functional regulation and signaling properties of Rap2B.

Qu D, Huang H, DI J, Gao K, Lu Z, Zheng J.

Oncol Lett. 2016 Apr;11(4):2339-2346. Epub 2016 Feb 23.


Phospholipase Cϵ Activates Nuclear Factor-κB Signaling by Causing Cytoplasmic Localization of Ribosomal S6 Kinase and Facilitating Its Phosphorylation of Inhibitor κB in Colon Epithelial Cells.

Wakita M, Edamatsu H, Li M, Emi A, Kitazawa S, Kataoka T.

J Biol Chem. 2016 Jun 10;291(24):12586-600. doi: 10.1074/jbc.M116.717561. Epub 2016 Apr 6.


The association between phospholipase C epsilon gene (PLCE1) polymorphisms and colorectal cancer risk in a Chinese Han population: a case-control study.

Zhang Y, Gong Y, Du S, Yan M, Geng T, Feng T, Wang J, Jin T.

Int J Clin Exp Med. 2015 Oct 15;8(10):19360-6. eCollection 2015.


Thrombin promotes sustained signaling and inflammatory gene expression through the CDC25 and Ras-associating domains of phospholipase Cϵ.

Dusaban SS, Kunkel MT, Smrcka AV, Brown JH.

J Biol Chem. 2015 Oct 30;290(44):26776-83. doi: 10.1074/jbc.M115.676098. Epub 2015 Sep 8.


Phosphoinositide-specific phospholipase C in health and disease.

Cocco L, Follo MY, Manzoli L, Suh PG.

J Lipid Res. 2015 Oct;56(10):1853-60. doi: 10.1194/jlr.R057984. Epub 2015 Mar 27. Review.


PLCε mediated sustained signaling pathways.

Dusaban SS, Brown JH.

Adv Biol Regul. 2015 Jan;57:17-23. doi: 10.1016/j.jbior.2014.09.014. Epub 2014 Oct 5. Review.


Comparison of potato and asian citrus psyllid adult and nymph transcriptomes identified vector transcripts with potential involvement in circulative, propagative liberibacter transmission.

Fisher TW, Vyas M, He R, Nelson W, Cicero JM, Willer M, Kim R, Kramer R, May GA, Crow JA, Soderlund CA, Gang DR, Brown JK.

Pathogens. 2014 Nov 3;3(4):875-907. doi: 10.3390/pathogens3040875.


Phospholipase cε, an effector of ras and rap small GTPases, is required for airway inflammatory response in a mouse model of bronchial asthma.

Nagano T, Edamatsu H, Kobayashi K, Takenaka N, Yamamoto M, Sasaki N, Nishimura Y, Kataoka T.

PLoS One. 2014 Sep 30;9(9):e108373. doi: 10.1371/journal.pone.0108373. eCollection 2014.


Rap2B promotes migration and invasion of human suprarenal epithelioma.

Di JH, Qu DB, Lu Z, Li LT, Cheng Q, Xin Y, Zhang LZ, Zhang Y, Zheng JN.

Tumour Biol. 2014 Sep;35(9):9387-94. doi: 10.1007/s13277-014-2174-8. Epub 2014 Jun 21.


Targeted activation of conventional and novel protein kinases C through differential translocation patterns.

Hui X, Reither G, Kaestner L, Lipp P.

Mol Cell Biol. 2014 Jul;34(13):2370-81. doi: 10.1128/MCB.00040-14. Epub 2014 Apr 14.


Phosphoinositides: tiny lipids with giant impact on cell regulation.

Balla T.

Physiol Rev. 2013 Jul;93(3):1019-137. doi: 10.1152/physrev.00028.2012. Review.


Phospholipase C epsilon links G protein-coupled receptor activation to inflammatory astrocytic responses.

Dusaban SS, Purcell NH, Rockenstein E, Masliah E, Cho MK, Smrcka AV, Brown JH.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3609-14. doi: 10.1073/pnas.1217355110. Epub 2013 Feb 11.


RNAi screening reveals a large signaling network controlling the Golgi apparatus in human cells.

Chia J, Goh G, Racine V, Ng S, Kumar P, Bard F.

Mol Syst Biol. 2012;8:629. doi: 10.1038/msb.2012.59.


Lysophospholipid receptor activation of RhoA and lipid signaling pathways.

Xiang SY, Dusaban SS, Brown JH.

Biochim Biophys Acta. 2013 Jan;1831(1):213-22. doi: 10.1016/j.bbalip.2012.09.004. Epub 2012 Sep 15. Review.


Potentially functional variants of PLCE1 identified by GWASs contribute to gastric adenocarcinoma susceptibility in an eastern Chinese population.

Wang M, Zhang R, He J, Qiu L, Li J, Wang Y, Sun M, Yang Y, Wang J, Yang J, Qian J, Jin L, Ma H, Wei Q, Zhou X.

PLoS One. 2012;7(3):e31932. doi: 10.1371/journal.pone.0031932. Epub 2012 Mar 6.


The phospholipase C isozymes and their regulation.

Gresset A, Sondek J, Harden TK.

Subcell Biochem. 2012;58:61-94. doi: 10.1007/978-94-007-3012-0_3. Review.


Role of phospholipase Cε in physiological phosphoinositide signaling networks.

Smrcka AV, Brown JH, Holz GG.

Cell Signal. 2012 Jun;24(6):1333-43. doi: 10.1016/j.cellsig.2012.01.009. Epub 2012 Jan 20. Review.


Mechanism of activation and inactivation of Gq/phospholipase C-β signaling nodes.

Harden TK, Waldo GL, Hicks SN, Sondek J.

Chem Rev. 2011 Oct 12;111(10):6120-9. doi: 10.1021/cr200209p. No abstract available.


Epac2-dependent rap1 activation and the control of islet insulin secretion by glucagon-like peptide-1.

Leech CA, Chepurny OG, Holz GG.

Vitam Horm. 2010;84:279-302. doi: 10.1016/B978-0-12-381517-0.00010-2. Review.


Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.

Gloerich M, Ponsioen B, Vliem MJ, Zhang Z, Zhao J, Kooistra MR, Price LS, Ritsma L, Zwartkruis FJ, Rehmann H, Jalink K, Bos JL.

Mol Cell Biol. 2010 Nov;30(22):5421-31. doi: 10.1128/MCB.00463-10. Epub 2010 Sep 20.

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