Items per page
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 1 to 20 of 47


Hypercholesterolemia, low density lipoprotein receptor and proprotein convertase subtilisin/kexin-type 9.

Gu HM, Zhang DW.

J Biomed Res. 2015 Sep;29(5):356-61. doi: 10.7555/JBR.29.20150067. Epub 2015 Jul 20. Review.


Intradomain Confinement of Disulfides in the Folding of Two Consecutive Modules of the LDL Receptor.

Martínez-Oliván J, Fraga H, Arias-Moreno X, Ventura S, Sancho J.

PLoS One. 2015 Jul 13;10(7):e0132141. doi: 10.1371/journal.pone.0132141. eCollection 2015.


Rare LRP6 variants identified in spina bifida patients.

Lei Y, Fathe K, McCartney D, Zhu H, Yang W, Ross ME, Shaw GM, Finnell RH.

Hum Mutat. 2015 Mar;36(3):342-9. doi: 10.1002/humu.22750.


Advantages and versatility of fluorescence-based methodology to characterize the functionality of LDLR and class mutation assignment.

Etxebarria A, Benito-Vicente A, Alves AC, Ostolaza H, Bourbon M, Martin C.

PLoS One. 2014 Nov 11;9(11):e112677. doi: 10.1371/journal.pone.0112677. eCollection 2014.


Use of targeted exome sequencing in genetic diagnosis of Chinese familial hypercholesterolemia.

Wu WF, Sun LY, Pan XD, Yang SW, Wang LY.

PLoS One. 2014 Apr 10;9(4):e94697. doi: 10.1371/journal.pone.0094697. eCollection 2014.


Functional characterization of two low-density lipoprotein receptor gene mutations in two Chinese patients with familial hypercholesterolemia.

Wang H, Xu S, Sun L, Pan X, Yang S, Wang L.

PLoS One. 2014 Mar 26;9(3):e92703. doi: 10.1371/journal.pone.0092703. eCollection 2014.


exomeSuite: Whole exome sequence variant filtering tool for rapid identification of putative disease causing SNVs/indels.

Maranhao B, Biswas P, Duncan JL, Branham KE, Silva GA, Naeem MA, Khan SN, Riazuddin S, Hejtmancik JF, Heckenlively JR, Riazuddin SA, Lee PL, Ayyagari R.

Genomics. 2014 Feb-Mar;103(2-3):169-76. doi: 10.1016/j.ygeno.2014.02.006. Epub 2014 Mar 3.


Genetic analysis of the relationship between bone mineral density and low-density lipoprotein receptor-related protein 5 gene polymorphisms.

Yi J, Cai Y, Yao Z, Lin J.

PLoS One. 2013 Dec 23;8(12):e85052. doi: 10.1371/journal.pone.0085052. eCollection 2013.


New horizons for lipoprotein receptors: communication by β-propellers.

Andersen OM, Dagil R, Kragelund BB.

J Lipid Res. 2013 Oct;54(10):2763-74. doi: 10.1194/jlr.M039545. Epub 2013 Jul 23.


The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations.

De Castro-Orós I, Pocoví M, Civeira F.

Appl Clin Genet. 2010 Aug 5;3:53-64. Print 2010.


Frizzled and LRP5/6 receptors for Wnt/β-catenin signaling.

MacDonald BT, He X.

Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12). pii: a007880. doi: 10.1101/cshperspect.a007880. Review.


LRP-1 and LRP-2 receptors function in the membrane neuron. Trafficking mechanisms and proteolytic processing in Alzheimer's disease.

Spuch C, Ortolano S, Navarro C.

Front Physiol. 2012 Jul 16;3:269. doi: 10.3389/fphys.2012.00269. eCollection 2012.


Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism.

Li X, Shan J, Chang W, Kim I, Bao J, Lee HJ, Zhang X, Samuel VT, Shulman GI, Liu D, Zheng JJ, Wu D.

Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11402-7. doi: 10.1073/pnas.1205015109. Epub 2012 Jun 25. Erratum in: Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17141.


Characterization of the interaction of sclerostin with the low density lipoprotein receptor-related protein (LRP) family of Wnt co-receptors.

Holdsworth G, Slocombe P, Doyle C, Sweeney B, Veverka V, Le Riche K, Franklin RJ, Compson J, Brookings D, Turner J, Kennedy J, Garlish R, Shi J, Newnham L, McMillan D, Muzylak M, Carr MD, Henry AJ, Ceska T, Robinson MK.

J Biol Chem. 2012 Aug 3;287(32):26464-77. doi: 10.1074/jbc.M112.350108. Epub 2012 Jun 13.


Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail.

Dvir H, Shah M, Girardi E, Guo L, Farquhar MG, Zajonc DM.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):6916-21. doi: 10.1073/pnas.1114128109. Epub 2012 Apr 16.


Near-membrane ensemble elongation in the proline-rich LRP6 intracellular domain may explain the mysterious initiation of the Wnt signaling pathway.

Liu C, Yao M, Hogue CW.

BMC Bioinformatics. 2011;12 Suppl 13:S13. doi: 10.1186/1471-2105-12-S13-S13. Epub 2011 Nov 30.


Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH.

Lo Surdo P, Bottomley MJ, Calzetta A, Settembre EC, Cirillo A, Pandit S, Ni YG, Hubbard B, Sitlani A, Carfí A.

EMBO Rep. 2011 Dec 1;12(12):1300-5. doi: 10.1038/embor.2011.205.


Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6.

Ahn VE, Chu ML, Choi HJ, Tran D, Abo A, Weis WI.

Dev Cell. 2011 Nov 15;21(5):862-73. doi: 10.1016/j.devcel.2011.09.003. Epub 2011 Oct 13.


Structural and functional studies of LRP6 ectodomain reveal a platform for Wnt signaling.

Chen S, Bubeck D, MacDonald BT, Liang WX, Mao JH, Malinauskas T, Llorca O, Aricescu AR, Siebold C, He X, Jones EY.

Dev Cell. 2011 Nov 15;21(5):848-61. doi: 10.1016/j.devcel.2011.09.007. Epub 2011 Oct 13.


Crystal structures of the extracellular domain of LRP6 and its complex with DKK1.

Cheng Z, Biechele T, Wei Z, Morrone S, Moon RT, Wang L, Xu W.

Nat Struct Mol Biol. 2011 Oct 9;18(11):1204-10. doi: 10.1038/nsmb.2139.

Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk