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Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

Naradikian MS, Myles A, Beiting DP, Roberts KJ, Dawson L, Herati RS, Bengsch B, Linderman SL, Stelekati E, Spolski R, Wherry EJ, Hunter C, Hensley SE, Leonard WJ, Cancro MP.

J Immunol. 2016 Aug 15;197(4):1023-8. doi: 10.4049/jimmunol.1600522. Epub 2016 Jul 18.


Regulation of Connexin43 Function and Expression by Tyrosine Kinase 2.

Li H, Spagnol G, Zheng L, Stauch KL, Sorgen PL.

J Biol Chem. 2016 Jul 22;291(30):15867-80. doi: 10.1074/jbc.M116.727008. Epub 2016 May 27.


Granulocyte colony-stimulating factor potentiates all-trans retinoic acid-induced granulocytic differentiation in acute promyelocytic leukemia cell line HT93A.

Uchino Y, Iriyama N, Hatta Y, Takei M.

Cancer Cell Int. 2015 Mar 12;15:30. doi: 10.1186/s12935-015-0176-2. eCollection 2015.


Chronic alcohol consumption potentiates the development of diabetes through pancreatic β-cell dysfunction.

Kim JY, Lee DY, Lee YJ, Park KJ, Kim KH, Kim JW, Kim WH.

World J Biol Chem. 2015 Feb 26;6(1):1-15. doi: 10.4331/wjbc.v6.i1.1. Review.


STAT3: A Novel Molecular Mediator of Resistance to Chemoradiotherapy.

Spitzner M, Ebner R, Wolff HA, Ghadimi BM, Wienands J, Grade M.

Cancers (Basel). 2014 Sep 29;6(4):1986-2011. doi: 10.3390/cancers6041986. Review.


Clinical utility of the oral JAK inhibitor tofacitinib in the treatment of rheumatoid arthritis.

Cutolo M, Meroni M.

J Inflamm Res. 2013 Nov 15;6:129-37. doi: 10.2147/JIR.S35901. eCollection 2013 Nov 15. Review.


Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases.

Patterson H, Nibbs R, McInnes I, Siebert S.

Clin Exp Immunol. 2014 Apr;176(1):1-10. doi: 10.1111/cei.12248. Review.


Regulation of STAT signaling by acetylation.

Zhuang S.

Cell Signal. 2013 Sep;25(9):1924-31. doi: 10.1016/j.cellsig.2013.05.007. Epub 2013 May 22. Review.


Safe and targeted anticancer therapy for ovarian cancer using a novel class of curcumin analogs.

Rath KS, McCann GA, Cohn DE, Rivera BK, Kuppusamy P, Selvendiran K.

J Ovarian Res. 2013 May 11;6(1):35. doi: 10.1186/1757-2215-6-35.


Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation.

Chen Z, Sun X, Shen S, Zhang H, Ma X, Liu J, Kuang S, Yu Q.

J Biol Chem. 2013 May 17;288(20):14417-27. doi: 10.1074/jbc.M112.442970. Epub 2013 Apr 11.


The kinase inhibitor tofacitinib in patients with rheumatoid arthritis: latest findings and clinical potential.

Cutolo M.

Ther Adv Musculoskelet Dis. 2013 Feb;5(1):3-11. doi: 10.1177/1759720X12470753.


Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells.

Nagy ZS, Ross JA, Rodriguez G, Balint BL, Szeles L, Nagy L, Kirken RA.

PLoS One. 2013;8(2):e57326. doi: 10.1371/journal.pone.0057326. Epub 2013 Feb 25. Erratum in: PLoS One. 2013;8(2). doi:10.1371/annotation/cb55d096-61f8-46de-b58f-81a872be6dd3.


Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.

Klatt NR, Estes JD, Sun X, Ortiz AM, Barber JS, Harris LD, Cervasi B, Yokomizo LK, Pan L, Vinton CL, Tabb B, Canary LA, Dang Q, Hirsch VM, Alter G, Belkaid Y, Lifson JD, Silvestri G, Milner JD, Paiardini M, Haddad EK, Brenchley JM.

Mucosal Immunol. 2012 Nov;5(6):646-57. doi: 10.1038/mi.2012.38. Epub 2012 May 30.


Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies.

Mitra A, Ross JA, Rodriguez G, Nagy ZS, Wilson HL, Kirken RA.

J Biol Chem. 2012 May 11;287(20):16596-608. doi: 10.1074/jbc.M111.319756. Epub 2012 Mar 22.


Kinase inhibitors in the treatment of immune-mediated disease.

Kontzias A, Laurence A, Gadina M, O'Shea JJ.

F1000 Med Rep. 2012;4:5. doi: 10.3410/M4-5. Epub 2012 Mar 1.


Janus kinase 3: the controller and the controlled.

Wu W, Sun XH.

Acta Biochim Biophys Sin (Shanghai). 2012 Mar;44(3):187-96. doi: 10.1093/abbs/gmr105. Epub 2011 Nov 29. Review.


A mechanism underlying NOTCH-induced and ubiquitin-mediated JAK3 degradation.

Wu W, Sun XH.

J Biol Chem. 2011 Dec 2;286(48):41153-62. doi: 10.1074/jbc.M111.273755. Epub 2011 Oct 3.


Opposing functions of IL-2 and IL-7 in the regulation of immune responses.

Katzman SD, Hoyer KK, Dooms H, Gratz IK, Rosenblum MD, Paw JS, Isakson SH, Abbas AK.

Cytokine. 2011 Oct;56(1):116-21. doi: 10.1016/j.cyto.2011.07.005. Epub 2011 Jul 31. Review.


Id1 has a physiological role in regulating early B lymphopoiesis.

Cochrane SW, Zhao Y, Perry SS, Urbaniak T, Sun XH.

Cell Mol Immunol. 2011 Jan;8(1):41-9. doi: 10.1038/cmi.2010.58. Epub 2010 Dec 6.

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