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Items: 1 to 20 of 152

1.

Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS.

Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, Gismondi A, Santoni A, Nisticò P.

Oncoimmunology. 2016 Feb 1;5(5):e1114203. doi: 10.1080/2162402X.2015.1114203. eCollection 2016 May.

2.

Loss of Immune Tolerance Is Controlled by ICOS in Sle1 Mice.

Mittereder N, Kuta E, Bhat G, Dacosta K, Cheng LI, Herbst R, Carlesso G.

J Immunol. 2016 Jul 15;197(2):491-503. doi: 10.4049/jimmunol.1502241. Epub 2016 Jun 13.

3.

Co-stimulatory and Co-inhibitory Pathways in Autoimmunity.

Zhang Q, Vignali DA.

Immunity. 2016 May 17;44(5):1034-51. doi: 10.1016/j.immuni.2016.04.017. Review.

PMID:
27192568
4.

A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.

Pedros C, Zhang Y, Hu JK, Choi YS, Canonigo-Balancio AJ, Yates JR 3rd, Altman A, Crotty S, Kong KF.

Nat Immunol. 2016 Jul;17(7):825-33. doi: 10.1038/ni.3463. Epub 2016 May 2.

PMID:
27135603
5.

Age-related impairment of humoral response to influenza is associated with changes in antigen specific T follicular helper cell responses.

Lefebvre JS, Masters AR, Hopkins JW, Haynes L.

Sci Rep. 2016 Apr 25;6:25051. doi: 10.1038/srep25051.

6.

Inducible T-cell co-stimulator ligand (ICOSL) blockade leads to selective inhibition of anti-KLH IgG responses in subjects with systemic lupus erythematosus.

Sullivan BA, Tsuji W, Kivitz A, Peng J, Arnold GE, Boedigheimer MJ, Chiu K, Green CL, Kaliyaperumal A, Wang C, Ferbas J, Chung JB.

Lupus Sci Med. 2016 Apr 8;3(1):e000146. doi: 10.1136/lupus-2016-000146. eCollection 2016.

7.

Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells.

Foy SP, Mandl SJ, Dela Cruz T, Cote JJ, Gordon EJ, Trent E, Delcayre A, Breitmeyer J, Franzusoff A, Rountree RB.

Cancer Immunol Immunother. 2016 May;65(5):537-49. doi: 10.1007/s00262-016-1816-7. Epub 2016 Mar 10.

8.

Retrogenic ICOS Expression Increases Differentiation of KLRG-1hiCD127loCD8+ T Cells during Listeria Infection and Diminishes Recall Responses.

Liu D, Burd EM, Coopersmith CM, Ford ML.

J Immunol. 2016 Feb 1;196(3):1000-12. doi: 10.4049/jimmunol.1500218. Epub 2016 Jan 4.

PMID:
26729800
9.

Tregs Modulate Lymphocyte Proliferation, Activation, and Resident-Memory T-Cell Accumulation within the Brain during MCMV Infection.

Prasad S, Hu S, Sheng WS, Singh A, Lokensgard JR.

PLoS One. 2015 Dec 31;10(12):e0145457. doi: 10.1371/journal.pone.0145457. eCollection 2015.

10.

T follicular helper cells, T follicular regulatory cells and autoimmunity.

Zhu Y, Zou L, Liu YC.

Int Immunol. 2016 Apr;28(4):173-9. doi: 10.1093/intimm/dxv079. Epub 2015 Dec 29. Review.

PMID:
26714592
11.

The Costimulatory Molecule ICOS Regulates Host Th1 and Follicular Th Cell Differentiation in Response to Plasmodium chabaudi chabaudi AS Infection.

Wikenheiser DJ, Ghosh D, Kennedy B, Stumhofer JS.

J Immunol. 2016 Jan 15;196(2):778-91. doi: 10.4049/jimmunol.1403206. Epub 2015 Dec 14.

12.

Good syndrome presenting with CD8⁺ T-Cell large granular lymphocyte leukemia.

Caperton C, Agrawal S, Gupta S.

Oncotarget. 2015 Nov 3;6(34):36577-86. doi: 10.18632/oncotarget.5369.

13.

Pulmonary sarcoidosis is associated with high-level inducible co-stimulator (ICOS) expression on lung regulatory T cells--possible implications for the ICOS/ICOS-ligand axis in disease course and resolution.

Sakthivel P, Grunewald J, Eklund A, Bruder D, Wahlström J.

Clin Exp Immunol. 2016 Feb;183(2):294-306. doi: 10.1111/cei.12715. Epub 2015 Nov 24.

PMID:
26415669
14.

The potential for chemical mixtures from the environment to enable the cancer hallmark of sustained proliferative signalling.

Engström W, Darbre P, Eriksson S, Gulliver L, Hultman T, Karamouzis MV, Klaunig JE, Mehta R, Moorwood K, Sanderson T, Sone H, Vadgama P, Wagemaker G, Ward A, Singh N, Al-Mulla F, Al-Temaimi R, Amedei A, Colacci AM, Vaccari M, Mondello C, Scovassi AI, Raju J, Hamid RA, Memeo L, Forte S, Roy R, Woodrick J, Salem HK, Ryan EP, Brown DG, Bisson WH.

Carcinogenesis. 2015 Jun;36 Suppl 1:S38-60. doi: 10.1093/carcin/bgv030. Review.

15.

Inhibition of Donor-Reactive CD8+ T Cell Responses by Selective CD28 Blockade Is Independent of Reduced ICOS Expression.

Liu D, Suchard SJ, Nadler SG, Ford ML.

PLoS One. 2015 Jun 22;10(6):e0130490. doi: 10.1371/journal.pone.0130490. eCollection 2015.

16.

Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice.

Kornete M, Mason ES, Girouard J, Lafferty EI, Qureshi S, Piccirillo CA.

PLoS One. 2015 May 6;10(5):e0126311. doi: 10.1371/journal.pone.0126311. eCollection 2015.

17.

ICOS:ICOS-ligand interaction is required for type 2 innate lymphoid cell function, homeostasis, and induction of airway hyperreactivity.

Maazi H, Patel N, Sankaranarayanan I, Suzuki Y, Rigas D, Soroosh P, Freeman GJ, Sharpe AH, Akbari O.

Immunity. 2015 Mar 17;42(3):538-51. doi: 10.1016/j.immuni.2015.02.007. Epub 2015 Mar 10.

18.

MicroRNA-146a regulates ICOS-ICOSL signalling to limit accumulation of T follicular helper cells and germinal centres.

Pratama A, Srivastava M, Williams NJ, Papa I, Lee SK, Dinh XT, Hutloff A, Jordan MA, Zhao JL, Casellas R, Athanasopoulos V, Vinuesa CG.

Nat Commun. 2015 Mar 6;6:6436. doi: 10.1038/ncomms7436.

19.

Generation of cellular immune memory and B-cell immunity is impaired by natural killer cells.

Rydyznski C, Daniels KA, Karmele EP, Brooks TR, Mahl SE, Moran MT, Li C, Sutiwisesak R, Welsh RM, Waggoner SN.

Nat Commun. 2015 Feb 27;6:6375. doi: 10.1038/ncomms7375.

20.

MAPK phosphatase 7 regulates T cell differentiation via inhibiting ERK-mediated IL-2 expression.

Zhang Y, Nallaparaju KC, Liu X, Jiao H, Reynolds JM, Wang ZX, Dong C.

J Immunol. 2015 Apr 1;194(7):3088-95. doi: 10.4049/jimmunol.1402638. Epub 2015 Feb 25.

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