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Items: 1 to 20 of 67

1.

Phosphorylation inactivation of endothelial nitric oxide synthesis in pulmonary arterial hypertension.

Ghosh S, Gupta M, Xu W, Mavrakis DA, Janocha AJ, Comhair SA, Haque MM, Stuehr DJ, Yu J, Polgar P, Naga Prasad SV, Erzurum SC.

Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1199-205. doi: 10.1152/ajplung.00092.2016. Epub 2016 Apr 29.

PMID:
27130529
2.

Endothelial nitric oxide synthase in the microcirculation.

Shu X, Keller TC 4th, Begandt D, Butcher JT, Biwer L, Keller AS, Columbus L, Isakson BE.

Cell Mol Life Sci. 2015 Dec;72(23):4561-75. doi: 10.1007/s00018-015-2021-0. Epub 2015 Aug 25. Review.

PMID:
26390975
3.

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo.

Bharath LP, Ruan T, Li Y, Ravindran A, Wan X, Nhan JK, Walker ML, Deeter L, Goodrich R, Johnson E, Munday D, Mueller R, Kunz D, Jones D, Reese V, Summers SA, Babu PV, Holland WL, Zhang QJ, Abel ED, Symons JD.

Diabetes. 2015 Nov;64(11):3914-26. doi: 10.2337/db15-0244. Epub 2015 Aug 7.

4.

Mechanisms and consequences of endothelial nitric oxide synthase dysfunction in hypertension.

Li Q, Youn JY, Cai H.

J Hypertens. 2015 Jun;33(6):1128-36. doi: 10.1097/HJH.0000000000000587. Review.

5.

Arsenite Acutely Decreases Nitric Oxide Production via the ROS-Protein Phosphatase 1-Endothelial Nitric Oxide Synthase-Thr(497) Signaling Cascade.

Seo J, Lee JY, Sung MS, Byun CJ, Cho DH, Lee HJ, Park JH, Cho HS, Cho SJ, Jo I.

Biomol Ther (Seoul). 2014 Nov;22(6):510-8. doi: 10.4062/biomolther.2014.106. Epub 2014 Nov 30.

6.

Angiotensin II-induced hypertension blunts thick ascending limb NO production by reducing NO synthase 3 expression and enhancing threonine 495 phosphorylation.

Ramseyer VD, Gonzalez-Vicente A, Carretero OA, Garvin JL.

Am J Physiol Renal Physiol. 2015 Jan 15;308(2):F149-56. doi: 10.1152/ajprenal.00279.2014. Epub 2014 Nov 5.

7.

Protection after stroke: cellular effectors of neurovascular unit integrity.

Posada-Duque RA, Barreto GE, Cardona-Gomez GP.

Front Cell Neurosci. 2014 Aug 14;8:231. doi: 10.3389/fncel.2014.00231. eCollection 2014. Review.

8.

Endothelial nitric oxide synthase dimerization is regulated by heat shock protein 90 rather than by phosphorylation.

Chen W, Xiao H, Rizzo AN, Zhang W, Mai Y, Ye M.

PLoS One. 2014 Aug 25;9(8):e105479. doi: 10.1371/journal.pone.0105479. eCollection 2014.

9.

PKC-dependent phosphorylation of eNOS at T495 regulates eNOS coupling and endothelial barrier function in response to G+ -toxins.

Chen F, Kumar S, Yu Y, Aggarwal S, Gross C, Wang Y, Chakraborty T, Verin AD, Catravas JD, Lucas R, Black SM, Fulton DJ.

PLoS One. 2014 Jul 14;9(7):e99823. doi: 10.1371/journal.pone.0099823. eCollection 2014.

10.

The N-terminal portion of autoinhibitory element modulates human endothelial nitric-oxide synthase activity through coordinated controls of phosphorylation at Thr495 and Ser1177.

Wu PR, Chen BR, Hsieh CC, Lin WC, Wu KK, Hwu Y, Chen PF.

Biosci Rep. 2014 Aug 6;34(4). pii: e00129. doi: 10.1042/BSR20140079.

11.

Reversal of SIN-1-induced eNOS dysfunction by the spin trap, DMPO, in bovine aortic endothelial cells via eNOS phosphorylation.

Das A, Gopalakrishnan B, Druhan LJ, Wang TY, De Pascali F, Rockenbauer A, Racoma I, Varadharaj S, Zweier JL, Cardounel AJ, Villamena FA.

Br J Pharmacol. 2014 May;171(9):2321-34. doi: 10.1111/bph.12572.

12.

Post-translational regulation of endothelial nitric oxide synthase in vascular endothelium.

Qian J, Fulton D.

Front Physiol. 2013 Dec 13;4:347. doi: 10.3389/fphys.2013.00347. Review.

13.

Interactive effects of in vitro binge-like alcohol and ATP on umbilical endothelial nitric oxide synthase post-translational modifications and redox modulation.

Subramanian K, Naik VD, Sathishkumar K, Sawant OB, Washburn SE, Wu G, Yallampalli C, Saade GR, Hankins GD, Ramadoss J.

Reprod Toxicol. 2014 Jan;43:94-101. doi: 10.1016/j.reprotox.2013.11.006. Epub 2013 Dec 1.

14.

Endothelial nitric oxide synthase uncoupling and microvascular dysfunction in the mesentery of mice deficient in α-galactosidase A.

Kang JJ, Shu L, Park JL, Shayman JA, Bodary PF.

Am J Physiol Gastrointest Liver Physiol. 2014 Jan;306(2):G140-6. doi: 10.1152/ajpgi.00185.2013. Epub 2013 Nov 14.

15.

Coordinated endothelial nitric oxide synthase activation by translocation and phosphorylation determines flow-induced nitric oxide production in resistance vessels.

Figueroa XF, González DR, Puebla M, Acevedo JP, Rojas-Libano D, Durán WN, Boric MP.

J Vasc Res. 2013;50(6):498-511. doi: 10.1159/000355301. Epub 2013 Nov 5.

16.

Regulation of eNOS enzyme activity by posttranslational modification.

Heiss EH, Dirsch VM.

Curr Pharm Des. 2014;20(22):3503-13. Review.

17.

Platelet activating factor-induced ceramide micro-domains drive endothelial NOS activation and contribute to barrier dysfunction.

Predescu S, Knezevic I, Bardita C, Neamu RF, Brovcovych V, Predescu D.

PLoS One. 2013 Sep 27;8(9):e75846. doi: 10.1371/journal.pone.0075846. eCollection 2013.

18.

Deficient eNOS phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size.

Li Q, Atochin D, Kashiwagi S, Earle J, Wang A, Mandeville E, Hayakawa K, d'Uscio LV, Lo EH, Katusic Z, Sessa W, Huang PL.

Stroke. 2013 Nov;44(11):3183-8. doi: 10.1161/STROKEAHA.113.002073. Epub 2013 Aug 29.

19.

Circulating endothelin-1 alters critical mechanisms regulating cerebral microcirculation.

Faraco G, Moraga A, Moore J, Anrather J, Pickel VM, Iadecola C.

Hypertension. 2013 Oct;62(4):759-66. doi: 10.1161/HYPERTENSIONAHA.113.01761. Epub 2013 Aug 19.

20.

Endothelial caveolar subcellular domain regulation of endothelial nitric oxide synthase.

Ramadoss J, Pastore MB, Magness RR.

Clin Exp Pharmacol Physiol. 2013 Nov;40(11):753-64. doi: 10.1111/1440-1681.12136. Review.

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