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Results: 1 to 20 of 39

Cited In for PubMed (Select 11331269)


Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5-SMG7 and SMG6.

Chakrabarti S, Bonneau F, Schüssler S, Eppinger E, Conti E.

Nucleic Acids Res. 2014 Aug;42(14):9447-60. doi: 10.1093/nar/gku578. Epub 2014 Jul 10.


Nonsense-mediated mRNA decay: inter-individual variability and human disease.

Nguyen LS, Wilkinson MF, Gecz J.

Neurosci Biobehav Rev. 2014 Oct;46 Pt 2:175-86. doi: 10.1016/j.neubiorev.2013.10.016. Epub 2013 Nov 14.


SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways.

Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T.

Cell Cycle. 2013 Dec 15;12(24):3770-80. doi: 10.4161/cc.26660. Epub 2013 Oct 4.


Comparison of EJC-enhanced and EJC-independent NMD in human cells reveals two partially redundant degradation pathways.

Metze S, Herzog VA, Ruepp MD, Mühlemann O.

RNA. 2013 Oct;19(10):1432-48. doi: 10.1261/rna.038893.113. Epub 2013 Aug 20.


DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans.

Longman D, Hug N, Keith M, Anastasaki C, Patton EE, Grimes G, Cáceres JF.

Nucleic Acids Res. 2013 Sep;41(17):8319-31. doi: 10.1093/nar/gkt585. Epub 2013 Jul 4.


Signaling pathways that control mRNA turnover.

Thapar R, Denmon AP.

Cell Signal. 2013 Aug;25(8):1699-710. doi: 10.1016/j.cellsig.2013.03.026. Epub 2013 Apr 16. Review.


An unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decay.

Jonas S, Weichenrieder O, Izaurralde E.

Genes Dev. 2013 Jan 15;27(2):211-25. doi: 10.1101/gad.206672.112.


NMD: a multifaceted response to premature translational termination.

Kervestin S, Jacobson A.

Nat Rev Mol Cell Biol. 2012 Nov;13(11):700-12. doi: 10.1038/nrm3454. Epub 2012 Oct 17. Review.


Balancing Arc synthesis, mRNA decay, and proteasomal degradation: maximal protein expression triggered by rapid eye movement sleep-like bursts of muscarinic cholinergic receptor stimulation.

Soulé J, Alme M, Myrum C, Schubert M, Kanhema T, Bramham CR.

J Biol Chem. 2012 Jun 22;287(26):22354-66. doi: 10.1074/jbc.M112.376491. Epub 2012 May 14.


SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians.

González-Estévez C, Felix DA, Smith MD, Paps J, Morley SJ, James V, Sharp TV, Aboobaker AA.

PLoS Genet. 2012;8(3):e1002619. doi: 10.1371/journal.pgen.1002619. Epub 2012 Mar 29.


Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1.

Kvas S, Gloor GB, Brandl CJ.

BMC Genet. 2012 Mar 22;13:19. doi: 10.1186/1471-2156-13-19.


A role for nonsense-mediated mRNA decay in plants: pathogen responses are induced in Arabidopsis thaliana NMD mutants.

Rayson S, Arciga-Reyes L, Wootton L, De Torres Zabala M, Truman W, Graham N, Grant M, Davies B.

PLoS One. 2012;7(2):e31917. doi: 10.1371/journal.pone.0031917. Epub 2012 Feb 22.


Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival.

Gubanova E, Brown B, Ivanov SV, Helleday T, Mills GB, Yarbrough WG, Issaeva N.

Clin Cancer Res. 2012 Mar 1;18(5):1257-67. doi: 10.1158/1078-0432.CCR-11-2058. Epub 2012 Jan 13.


The RNA surveillance protein SMG1 activates p53 in response to DNA double-strand breaks but not exogenously oxidized mRNA.

Gewandter JS, Bambara RA, O'Reilly MA.

Cell Cycle. 2011 Aug 1;10(15):2561-7. Epub 2011 Aug 1.


SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay.

Kashima I, Jonas S, Jayachandran U, Buchwald G, Conti E, Lupas AN, Izaurralde E.

Genes Dev. 2010 Nov 1;24(21):2440-50. doi: 10.1101/gad.604610. Epub 2010 Oct 7.


Smg1 is required for embryogenesis and regulates diverse genes via alternative splicing coupled to nonsense-mediated mRNA decay.

McIlwain DR, Pan Q, Reilly PT, Elia AJ, McCracken S, Wakeham AC, Itie-Youten A, Blencowe BJ, Mak TW.

Proc Natl Acad Sci U S A. 2010 Jul 6;107(27):12186-91. doi: 10.1073/pnas.1007336107. Epub 2010 Jun 21.


Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII.

Dang Y, Low WK, Xu J, Gehring NH, Dietz HC, Romo D, Liu JO.

J Biol Chem. 2009 Aug 28;284(35):23613-21. doi: 10.1074/jbc.M109.009985. Epub 2009 Jul 1.


Rapamycin and mTOR kinase inhibitors.

Ballou LM, Lin RZ.

J Chem Biol. 2008 Nov;1(1-4):27-36. doi: 10.1007/s12154-008-0003-5. Epub 2008 May 15.


Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival.

Wittkopp N, Huntzinger E, Weiler C, Saulière J, Schmidt S, Sonawane M, Izaurralde E.

Mol Cell Biol. 2009 Jul;29(13):3517-28. doi: 10.1128/MCB.00177-09. Epub 2009 May 4.


Kinome siRNA screen identifies SMG-1 as a negative regulator of hypoxia-inducible factor-1alpha in hypoxia.

Chen RQ, Yang QK, Chen YL, Oliveira VA, Dalton WS, Fearns C, Lee JD.

J Biol Chem. 2009 Jun 19;284(25):16752-8. doi: 10.1074/jbc.M109.014316. Epub 2009 Apr 30.

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