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Results: 17

1.

Macromolecular prodrug of dexamethasone prevents particle-induced peri-implant osteolysis with reduced systemic side effects.

Ren K, Dusad A, Yuan F, Yuan H, Purdue PE, Fehringer EV, Garvin KL, Goldring SR, Wang D.

J Control Release. 2014 Feb 10;175:1-9. doi: 10.1016/j.jconrel.2013.11.024. Epub 2013 Dec 8.

PMID:
24326124
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Anti-oxidation treatment of ultra high molecular weight polyethylene components to decrease periprosthetic osteolysis: evaluation of osteolytic and osteogenic properties of wear debris particles in a murine calvaria model.

Green JM, Hallab NJ, Liao YS, Narayan V, Schwarz EM, Xie C.

Curr Rheumatol Rep. 2013 May;15(5):325. doi: 10.1007/s11926-013-0325-3. Review.

PMID:
23532463
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Periprosthetic osteolysis: genetics, mechanisms and potential therapeutic interventions.

Noordin S, Masri B.

Can J Surg. 2012 Dec;55(6):408-17. doi: 10.1503/cjs.003711. Review.

PMID:
22992398
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Prostaglandin E(2) binding peptide screened by phage displaying: a new therapeutic strategy in rheumatoid arthritis.

Yan D, Han W, Bai Q, Zhao X, Han X, Du B, Zhu X.

Lipids Health Dis. 2011 May 14;10:75. doi: 10.1186/1476-511X-10-75.

PMID:
21569552
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

New animal models of wear-particle osteolysis.

Langlois J, Hamadouche M.

Int Orthop. 2011 Feb;35(2):245-51. doi: 10.1007/s00264-010-1143-0. Epub 2010 Nov 12. Review.

PMID:
21069525
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

In vivo imaging of particle-induced inflammation and osteolysis in the calvariae of NFκB/luciferase transgenic mice.

Takahashi K, Onodera S, Tohyama H, Kwon HJ, Honma K, Yasuda K.

J Biomed Biotechnol. 2011;2011. pii: 727063. doi: 10.1155/2011/727063. Epub 2010 Sep 21.

PMID:
20936177
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Index radial collateral ligament repair with titanium mini-suture anchor: osteolysis complication of an underreported injury.

Mirza A, Reinhart MK, Bove JJ.

Hand (N Y). 2010 Sep;5(3):294-8. doi: 10.1007/s11552-009-9230-7. Epub 2009 Oct 14.

PMID:
19826880
[PubMed]
Free PMC Article
8.

Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-kappaB pathway.

Wei X, Zhang X, Flick LM, Drissi H, Schwarz EM, O'Keefe RJ.

Am J Physiol Cell Physiol. 2009 Aug;297(2):C310-20. doi: 10.1152/ajpcell.00597.2008. Epub 2009 Jun 3.

PMID:
19494233
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The effect of Lipoxin A4 on the interaction between macrophage and osteoblast: possible role in the treatment of aseptic loosening.

Li G, Wu P, Xu Y, Yu Y, Sun L, Zhu L, Ye D.

BMC Musculoskelet Disord. 2009 Jun 2;10:57. doi: 10.1186/1471-2474-10-57.

PMID:
19490628
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

PGE2 signaling through the EP4 receptor on fibroblasts upregulates RANKL and stimulates osteolysis.

Tsutsumi R, Xie C, Wei X, Zhang M, Zhang X, Flick LM, Schwarz EM, O'Keefe RJ.

J Bone Miner Res. 2009 Oct;24(10):1753-62. doi: 10.1359/jbmr.090412.

PMID:
19419302
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Reduced COX-2 expression in aged mice is associated with impaired fracture healing.

Naik AA, Xie C, Zuscik MJ, Kingsley P, Schwarz EM, Awad H, Guldberg R, Drissi H, Puzas JE, Boyce B, Zhang X, O'Keefe RJ.

J Bone Miner Res. 2009 Feb;24(2):251-64. doi: 10.1359/jbmr.081002.

PMID:
18847332
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

COX-2 from the injury milieu is critical for the initiation of periosteal progenitor cell mediated bone healing.

Xie C, Ming X, Wang Q, Schwarz EM, Guldberg RE, O'Keefe RJ, Zhang X.

Bone. 2008 Dec;43(6):1075-83. doi: 10.1016/j.bone.2008.08.109. Epub 2008 Aug 16.

PMID:
18773980
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The central role of wear debris in periprosthetic osteolysis.

Purdue PE, Koulouvaris P, Nestor BJ, Sculco TP.

HSS J. 2006 Sep;2(2):102-13. doi: 10.1007/s11420-006-9003-6.

PMID:
18751821
[PubMed]
Free PMC Article
14.

Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT.

Tsutsumi R, Hock C, Bechtold CD, Proulx ST, Bukata SV, Ito H, Awad HA, Nakamura T, O'Keefe RJ, Schwarz EM.

J Orthop Res. 2008 Oct;26(10):1340-6. doi: 10.1002/jor.20620.

PMID:
18404739
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Alteration of femoral bone morphology and density in COX-2-/- mice.

Robertson G, Xie C, Chen D, Awad H, Schwarz EM, O'Keefe RJ, Guldberg RE, Zhang X.

Bone. 2006 Oct;39(4):767-72. Epub 2006 May 30.

PMID:
16731065
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency.

Carmouche JJ, Puzas JE, Zhang X, Tiyapatanaputi P, Cory-Slechta DA, Gelein R, Zuscik M, Rosier RN, Boyce BF, O'Keefe RJ, Schwarz EM.

Environ Health Perspect. 2005 Jun;113(6):749-55.

PMID:
15929899
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.

Zhang X, Schwarz EM, Young DA, Puzas JE, Rosier RN, O'Keefe RJ.

J Clin Invest. 2002 Jun;109(11):1405-15. Erratum in: J Clin Invest 2002 Oct;110(8):1211.

PMID:
12045254
[PubMed - indexed for MEDLINE]
Free PMC Article
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