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Donor age and long-term culture do not negatively influence the stem potential of limbal fibroblast-like stem cells.

Tomasello L, Musso R, Cillino G, Pitrone M, Pizzolanti G, Coppola A, Arancio W, Di Cara G, Pucci-Minafra I, Cillino S, Giordano C.

Stem Cell Res Ther. 2016 Jun 13;7(1):83. doi: 10.1186/s13287-016-0342-z. Erratum in: Stem Cell Res Ther. 2016;7(1):106.


PFN2, a novel marker of unfavorable prognosis, is a potential therapeutic target involved in esophageal squamous cell carcinoma.

Cui XB, Zhang SM, Xu YX, Dang HW, Liu CX, Wang LH, Yang L, Hu JM, Liang WH, Jiang JF, Li N, Li Y, Chen YZ, Li F.

J Transl Med. 2016 May 17;14(1):137. doi: 10.1186/s12967-016-0884-y.


Neuronal profilins in health and disease: Relevance for spine plasticity and Fragile X syndrome.

Michaelsen-Preusse K, Zessin S, Grigoryan G, Scharkowski F, Feuge J, Remus A, Korte M.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3365-70. doi: 10.1073/pnas.1516697113. Epub 2016 Mar 7.


Profilin Interaction with Actin Filament Barbed End Controls Dynamic Instability, Capping, Branching, and Motility.

Pernier J, Shekhar S, Jegou A, Guichard B, Carlier MF.

Dev Cell. 2016 Jan 25;36(2):201-14. doi: 10.1016/j.devcel.2015.12.024.


Protein interaction patterns in different cellular environments are revealed by in-cell NMR.

Barbieri L, Luchinat E, Banci L.

Sci Rep. 2015 Sep 24;5:14456. doi: 10.1038/srep14456.


Subcellular localization and Ser-137 phosphorylation regulate tumor-suppressive activity of profilin-1.

Diamond MI, Cai S, Boudreau A, Carey CJ Jr, Lyle N, Pappu RV, Swamidass SJ, Bissell M, Piwnica-Worms H, Shao J.

J Biol Chem. 2015 Apr 3;290(14):9075-86. doi: 10.1074/jbc.M114.619874. Epub 2015 Feb 13.


Profilin isoforms modulate astrocytic morphology and the motility of astrocytic processes.

Schweinhuber SK, Meßerschmidt T, Hänsch R, Korte M, Rothkegel M.

PLoS One. 2015 Jan 28;10(1):e0117244. doi: 10.1371/journal.pone.0117244. eCollection 2015.


Profilin regulates F-actin network homeostasis by favoring formin over Arp2/3 complex.

Suarez C, Carroll RT, Burke TA, Christensen JR, Bestul AJ, Sees JA, James ML, Sirotkin V, Kovar DR.

Dev Cell. 2015 Jan 12;32(1):43-53. doi: 10.1016/j.devcel.2014.10.027. Epub 2014 Dec 24.


Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1α axis.

Yao W, Ji S, Qin Y, Yang J, Xu J, Zhang B, Xu W, Liu J, Shi S, Liu L, Liu C, Long J, Ni Q, Li M, Yu X.

Mol Cancer. 2014 Aug 7;13:187. doi: 10.1186/1476-4598-13-187.


S137 phosphorylation of profilin 1 is an important signaling event in breast cancer progression.

Rizwani W, Fasim A, Sharma D, Reddy DJ, Bin Omar NA, Singh SS.

PLoS One. 2014 Aug 1;9(8):e103868. doi: 10.1371/journal.pone.0103868. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e114164.


The DCR protein TTC3 affects differentiation and Golgi compactness in neurons through specific actin-regulating pathways.

Berto GE, Iobbi C, Camera P, Scarpa E, Iampietro C, Bianchi F, Gai M, Sgrò F, Cristofani F, Gärtner A, Dotti CG, Di Cunto F.

PLoS One. 2014 Apr 2;9(4):e93721. doi: 10.1371/journal.pone.0093721. eCollection 2014.


Actin filaments at the leading edge of cancer cells are characterized by a high mobile fraction and turnover regulation by profilin I.

Lorente G, Syriani E, Morales M.

PLoS One. 2014 Jan 17;9(1):e85817. doi: 10.1371/journal.pone.0085817. eCollection 2014.


Profilin 1 is essential for retention and metabolism of mouse hematopoietic stem cells in bone marrow.

Zheng J, Lu Z, Kocabas F, Böttcher RT, Costell M, Kang X, Liu X, Deberardinis RJ, Wang Q, Chen GQ, Sadek H, Zhang CC.

Blood. 2014 Feb 13;123(7):992-1001. doi: 10.1182/blood-2013-04-498469. Epub 2014 Jan 2.


Analysis of the effects of polymorphism on pollen profilin structural functionality and the generation of conformational, T- and B-cell epitopes.

Jimenez-Lopez JC, Rodríguez-García MI, Alché JD.

PLoS One. 2013 Oct 17;8(10):e76066. doi: 10.1371/journal.pone.0076066. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/3008c3af-753f-4085-b85e-5ae0c34a7889.


Novel anti-HIV therapeutics targeting chemokine receptors and actin regulatory pathways.

Spear M, Guo J, Wu Y.

Immunol Rev. 2013 Nov;256(1):300-12. doi: 10.1111/imr.12106. Review.


Profilin-1 haploinsufficiency protects against obesity-associated glucose intolerance and preserves adipose tissue immune homeostasis.

Romeo GR, Pae M, Eberlé D, Lee J, Shoelson SE.

Diabetes. 2013 Nov;62(11):3718-26. doi: 10.2337/db13-0050. Epub 2013 Jul 24.


Maternal factors required for oocyte developmental competence in mice: transcriptome analysis of non-surrounded nucleolus (NSN) and surrounded nucleolus (SN) oocytes.

Ma JY, Li M, Luo YB, Song S, Tian D, Yang J, Zhang B, Hou Y, Schatten H, Liu Z, Sun QY.

Cell Cycle. 2013 Jun 15;12(12):1928-38. doi: 10.4161/cc.24991. Epub 2013 May 13.


Molecular insights on context-specific role of profilin-1 in cell migration.

Ding Z, Bae YH, Roy P.

Cell Adh Migr. 2012 Sep-Oct;6(5):442-9. doi: 10.4161/cam.21832. Epub 2012 Sep 1. Review.


Stimulus-dependent phosphorylation of profilin-1 in angiogenesis.

Fan Y, Arif A, Gong Y, Jia J, Eswarappa SM, Willard B, Horowitz A, Graham LM, Penn MS, Fox PL.

Nat Cell Biol. 2012 Oct;14(10):1046-56. doi: 10.1038/ncb2580. Epub 2012 Sep 23.


Transcriptional regulation of Profilin during wound closure in Drosophila larvae.

Brock AR, Wang Y, Berger S, Renkawitz-Pohl R, Han VC, Wu Y, Galko MJ.

J Cell Sci. 2012 Dec 1;125(Pt 23):5667-76. doi: 10.1242/jcs.107490. Epub 2012 Sep 12.

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