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Sustained Suppression of Hyperalgesia during Latent Sensitization by μ-, δ-, and κ-opioid receptors and α2A Adrenergic Receptors: Role of Constitutive Activity.

Walwyn WM, Chen W, Kim H, Minasyan A, Ennes HS, McRoberts JA, Marvizón JC.

J Neurosci. 2016 Jan 6;36(1):204-21. doi: 10.1523/JNEUROSCI.1751-15.2016.


International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin Receptors: Interpreters of Pathophysiological Angiotensinergic Stimuli [corrected].

Karnik SS, Unal H, Kemp JR, Tirupula KC, Eguchi S, Vanderheyden PM, Thomas WG.

Pharmacol Rev. 2015 Oct;67(4):754-819. doi: 10.1124/pr.114.010454. Review. Erratum in: Pharmacol Rev. 2015 Oct;67(4):820.


Pharmacological properties of acid N-thiazolylamide FFA2 agonists.

Brown AJ, Tsoulou C, Ward E, Gower E, Bhudia N, Chowdhury F, Dean TW, Faucher N, Gangar A, Dowell SJ.

Pharmacol Res Perspect. 2015 Jun;3(3):e00141. doi: 10.1002/prp2.141. Epub 2015 May 8.


Peptide ligand recognition by G protein-coupled receptors.

Krumm BE, Grisshammer R.

Front Pharmacol. 2015 Mar 16;6:48. doi: 10.3389/fphar.2015.00048. eCollection 2015. Review.


Defect in MAPK signaling as a cause for monogenic obesity caused by inactivating mutations in the melanocortin-4 receptor gene.

He S, Tao YX.

Int J Biol Sci. 2014 Oct 9;10(10):1128-37. doi: 10.7150/ijbs.10359. eCollection 2014.


Nucleus accumbens shell excitability is decreased by methamphetamine self-administration and increased by 5-HT2C receptor inverse agonism and agonism.

Graves SM, Clark MJ, Traynor JR, Hu XT, Napier TC.

Neuropharmacology. 2015 Feb;89:113-21. doi: 10.1016/j.neuropharm.2014.09.001. Epub 2014 Sep 16.


Endogenous analgesia, dependence, and latent pain sensitization.

Taylor BK, Corder G.

Curr Top Behav Neurosci. 2014;20:283-325. doi: 10.1007/7854_2014_351.


Expression of dual nucleotides/cysteinyl-leukotrienes receptor GPR17 in early trafficking of cardiac stromal cells after myocardial infarction.

Cosentino S, Castiglioni L, Colazzo F, Nobili E, Tremoli E, Rosa P, Abbracchio MP, Sironi L, Pesce M.

J Cell Mol Med. 2014 Sep;18(9):1785-96. doi: 10.1111/jcmm.12305. Epub 2014 Jun 7.


Molecular determinants for the high constitutive activity of the human histamine H4 receptor: functional studies on orthologues and mutants.

Wifling D, Löffel K, Nordemann U, Strasser A, Bernhardt G, Dove S, Seifert R, Buschauer A.

Br J Pharmacol. 2015 Feb;172(3):785-98. doi: 10.1111/bph.12801. Epub 2014 Sep 5.


The natural product magnolol as a lead structure for the development of potent cannabinoid receptor agonists.

Fuchs A, Rempel V, Müller CE.

PLoS One. 2013 Oct 30;8(10):e77739. doi: 10.1371/journal.pone.0077739. eCollection 2013.


Constitutive μ-opioid receptor activity leads to long-term endogenous analgesia and dependence.

Corder G, Doolen S, Donahue RR, Winter MK, Jutras BL, He Y, Hu X, Wieskopf JS, Mogil JS, Storm DR, Wang ZJ, McCarson KE, Taylor BK.

Science. 2013 Sep 20;341(6152):1394-9. doi: 10.1126/science.1239403. Erratum in: Science. 2013 Nov 8;342(6159):693.


Signalling profile differences: paliperidone versus risperidone.

Clarke WP, Chavera TA, Silva M, Sullivan LC, Berg KA.

Br J Pharmacol. 2013 Oct;170(3):532-45. doi: 10.1111/bph.12295.


Characterization of three vasopressin receptor 2 variants: an apparent polymorphism (V266A) and two loss-of-function mutations (R181C and M311V).

Armstrong SP, Seeber RM, Ayoub MA, Feldman BJ, Pfleger KD.

PLoS One. 2013 Jun 6;8(6):e65885. doi: 10.1371/journal.pone.0065885. Print 2013.


Characterization of cannabinoid receptor ligands in tissues natively expressing cannabinoid CB2 receptors.

Marini P, Cascio MG, King A, Pertwee RG, Ross RA.

Br J Pharmacol. 2013 Jun;169(4):887-99. doi: 10.1111/bph.12191.


Extracellular ionic locks determine variation in constitutive activity and ligand potency between species orthologs of the free fatty acid receptors FFA2 and FFA3.

Hudson BD, Tikhonova IG, Pandey SK, Ulven T, Milligan G.

J Biol Chem. 2012 Nov 30;287(49):41195-209. doi: 10.1074/jbc.M112.396259. Epub 2012 Oct 12.


The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice.

Maximov PY, Lee TM, Jordan VC.

Curr Clin Pharmacol. 2013 May;8(2):135-55. Review.


New concepts in pharmacological efficacy at 7TM receptors: IUPHAR review 2.

Kenakin T.

Br J Pharmacol. 2013 Feb;168(3):554-75. doi: 10.1111/j.1476-5381.2012.02223.x. Review.


Novel Bradykinin Analogues Modified in the N-Terminal Part of the Molecule with a Variety of Acyl Substituents.

Sleszyńska M, Wierzba TH, Malinowski K, Tůmová T, Lammek B, Slaninová J, Prahl A.

Int J Pept Res Ther. 2012 Jun;18(2):117-124. Epub 2012 Jan 3.


Crystal structures of a stabilized β1-adrenoceptor bound to the biased agonists bucindolol and carvedilol.

Warne T, Edwards PC, Leslie AG, Tate CG.

Structure. 2012 May 9;20(5):841-9. doi: 10.1016/j.str.2012.03.014.


Cannabinoid receptors: nomenclature and pharmacological principles.

Console-Bram L, Marcu J, Abood ME.

Prog Neuropsychopharmacol Biol Psychiatry. 2012 Jul 2;38(1):4-15. doi: 10.1016/j.pnpbp.2012.02.009. Epub 2012 Feb 28. Review.

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