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Results: 1 to 20 of 141

1.

Involvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens.

Ibrahim MY, Hashim NM, Mohan S, Abdulla MA, Abdelwahab SI, Kamalidehghan B, Ghaderian M, Dehghan F, Ali LZ, Karimian H, Yahayu M, Ee GC, Farjam AS, Ali HM.

Drug Des Devel Ther. 2014 Nov 6;8:2193-211. doi: 10.2147/DDDT.S66574. eCollection 2014.

PMID:
25395836
[PubMed - in process]
Free PMC Article
2.

Smac/DIABLO expression in human gastrointestinal carcinoma: Association with clinicopathological parameters and survivin expression.

Shintani M, Sangawa A, Yamao N, Kamoshida S.

Oncol Lett. 2014 Dec;8(6):2581-2586. Epub 2014 Oct 9.

PMID:
25364431
[PubMed]
Free PMC Article
3.

α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and Hsp70 protein modulation in vitro, and tumor reduction in vivo.

Ibrahim MY, Hashim NM, Mohan S, Abdulla MA, Kamalidehghan B, Ghaderian M, Dehghan F, Ali LZ, Arbab IA, Yahayu M, Lian GE, Ahmadipour F, Ali HM.

Drug Des Devel Ther. 2014 Sep 27;8:1629-47. doi: 10.2147/DDDT.S66105. eCollection 2014.

PMID:
25302018
[PubMed - in process]
Free PMC Article
4.

In vivo overexpression of X-linked inhibitor of apoptosis protein protects against neomycin-induced hair cell loss in the apical turn of the cochlea during the ototoxic-sensitive period.

Sun S, Sun M, Zhang Y, Cheng C, Waqas M, Yu H, He Y, Xu B, Wang L, Wang J, Yin S, Chai R, Li H.

Front Cell Neurosci. 2014 Sep 15;8:248. doi: 10.3389/fncel.2014.00248. eCollection 2014.

PMID:
25278835
[PubMed]
Free PMC Article
5.

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

Seiter MA, Salcher S, Rupp M, Hagenbuchner J, Kiechl-Kohlendorfer U, Mortier J, Wolber G, Rollinger JM, Obexer P, Ausserlechner MJ.

FEBS Open Bio. 2014 Jul 5;4:659-71. doi: 10.1016/j.fob.2014.07.001. eCollection 2014.

PMID:
25161875
[PubMed]
Free PMC Article
6.

X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.

Obexer P, Ausserlechner MJ.

Front Oncol. 2014 Jul 28;4:197. doi: 10.3389/fonc.2014.00197. eCollection 2014. Review.

PMID:
25120954
[PubMed]
Free PMC Article
7.

SMAC Mimetic BV6 Enables Sensitization of Resistant Tumor Cells but also Affects Cytokine-Induced Killer (CIK) Cells: A Potential Challenge for Combination Therapy.

Rettinger E, Glatthaar A, Abhari BA, Oelsner S, Pfirrmann V, Huenecke S, Kuçi S, Kreyenberg H, Willasch AM, Klingebiel T, Fulda S, Bader P.

Front Pediatr. 2014 Jul 18;2:75. doi: 10.3389/fped.2014.00075. eCollection 2014.

PMID:
25101252
[PubMed]
Free PMC Article
8.

In vitro cytotoxicity of Artemisia vulgaris L. essential oil is mediated by a mitochondria-dependent apoptosis in HL-60 leukemic cell line.

Saleh AM, Aljada A, Rizvi SA, Nasr A, Alaskar AS, Williams JD.

BMC Complement Altern Med. 2014 Jul 7;14:226. doi: 10.1186/1472-6882-14-226.

PMID:
25002129
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases.

Dagbay K, Eron SJ, Serrano BP, Velázquez-Delgado EM, Zhao Y, Lin D, Vaidya S, Hardy JA.

Methods Enzymol. 2014;544:215-49. doi: 10.1016/B978-0-12-417158-9.00009-1.

PMID:
24974292
[PubMed - in process]
Free PMC Article
10.
11.

Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs).

Berthelet J, Dubrez L.

Cells. 2013 Mar 14;2(1):163-87. doi: 10.3390/cells2010163.

PMID:
24709650
[PubMed]
Free PMC Article
12.

Differential sensitivity to apoptosome apparatus activation in non-small cell lung carcinoma and the lung.

Moravcikova E, Krepela E, Prochazka J, Benkova K, Pauk N.

Int J Oncol. 2014 May;44(5):1443-54. doi: 10.3892/ijo.2014.2333. Epub 2014 Mar 10.

PMID:
24626292
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Survivin as a preferential target for cancer therapy.

Mobahat M, Narendran A, Riabowol K.

Int J Mol Sci. 2014 Feb 13;15(2):2494-516. doi: 10.3390/ijms15022494.

PMID:
24531137
[PubMed - in process]
Free PMC Article
14.

Radiation-induced cytochrome c release and the neuroprotective effects of the pan-caspase inhibitor z-VAD-fmk in the hypoglossal nucleus.

Li J, Wang Y, DU L, Xu C, Cao J, Wang Q, Liu Q, Fan F.

Exp Ther Med. 2014 Feb;7(2):383-388. Epub 2013 Nov 20.

PMID:
24396410
[PubMed]
Free PMC Article
15.

Radiation-sensitising effects of antennapedia proteins (ANTP)-SmacN7 on tumour cells.

Du LQ, Wang Y, Xu C, Cao J, Wang Q, Zhao H, Fan FY, Wang B, Katsube T, Fan SJ, Liu Q.

Int J Mol Sci. 2013 Dec 11;14(12):24087-96. doi: 10.3390/ijms141224087.

PMID:
24336110
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity.

Lecis D, De Cesare M, Perego P, Conti A, Corna E, Drago C, Seneci P, Walczak H, Colombo MP, Delia D, Sangaletti S.

Cell Death Dis. 2013 Nov 14;4:e920. doi: 10.1038/cddis.2013.449.

PMID:
24232096
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

IAP proteins as targets for drug development in oncology.

Dubrez L, Berthelet J, Glorian V.

Onco Targets Ther. 2013 Sep 16;9:1285-304. doi: 10.2147/OTT.S33375. Review.

PMID:
24092992
[PubMed]
Free PMC Article
18.

The structure of XIAP BIR2: understanding the selectivity of the BIR domains.

Lukacs C, Belunis C, Crowther R, Danho W, Gao L, Goggin B, Janson CA, Li S, Remiszewski S, Schutt A, Thakur MK, Singh SK, Swaminathan S, Pandey R, Tyagi R, Gosu R, Kamath AV, Kuglstatter A.

Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1717-25. doi: 10.1107/S0907444913016284. Epub 2013 Aug 15.

PMID:
23999295
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Caspase substrates and inhibitors.

Poreba M, Strózyk A, Salvesen GS, Drag M.

Cold Spring Harb Perspect Biol. 2013 Aug 1;5(8):a008680. doi: 10.1101/cshperspect.a008680. Review.

PMID:
23788633
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Targeting protein-protein interactions as an anticancer strategy.

Ivanov AA, Khuri FR, Fu H.

Trends Pharmacol Sci. 2013 Jul;34(7):393-400. doi: 10.1016/j.tips.2013.04.007. Epub 2013 May 29. Review.

PMID:
23725674
[PubMed - indexed for MEDLINE]
Free PMC Article

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