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Items: 1 to 20 of 37


STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.

Dulek DE, Newcomb DC, Toki S, Goliniewska K, Cephus J, Reiss S, Bates JT, Crowe JE Jr, Boyd KL, Moore ML, Zhou W, Peebles RS Jr.

J Virol. 2014 Sep 1;88(17):9655-72. doi: 10.1128/JVI.03299-13. Epub 2014 Jun 11.


Host-Viral Interactions: Role of Pattern Recognition Receptors (PRRs) in Human Pneumovirus Infections.

Kolli D, Velayutham TS, Casola A.

Pathogens. 2013 Jun 1;2(2). doi: 10.3390/pathogens2020232.


Wheezing and itching: The requirement for STAT proteins in allergic inflammation.

Glosson NL, Bruns HA, Kaplan MH.

JAKSTAT. 2012 Jan 1;1(1):3-12. doi: 10.4161/jkst.19086. Review.


The respiratory syncytial virus fusion protein and neutrophils mediate the airway mucin response to pathogenic respiratory syncytial virus infection.

Stokes KL, Currier MG, Sakamoto K, Lee S, Collins PL, Plemper RK, Moore ML.

J Virol. 2013 Sep;87(18):10070-82. doi: 10.1128/JVI.01347-13. Epub 2013 Jul 10.


Dual role of interleukin-10 in the regulation of respiratory syncitial virus (RSV)-induced lung inflammation.

Sun L, Cornell TT, LeVine A, Berlin AA, Hinkovska-Galcheva V, Fleszar AJ, Lukacs NW, Shanley TP.

Clin Exp Immunol. 2013 May;172(2):263-79. doi: 10.1111/cei.12059.


IL-4Rα on CD4+ T cells plays a pathogenic role in respiratory syncytial virus reinfection in mice infected initially as neonates.

You D, Marr N, Saravia J, Shrestha B, Lee GI, Turvey SE, Brombacher F, Herbert DR, Cormier SA.

J Leukoc Biol. 2013 Jun;93(6):933-42. doi: 10.1189/jlb.1012498. Epub 2013 Mar 29.


TSLP promotes induction of Th2 differentiation but is not necessary during established allergen-induced pulmonary disease.

Jang S, Morris S, Lukacs NW.

PLoS One. 2013;8(2):e56433. doi: 10.1371/journal.pone.0056433. Epub 2013 Feb 20.


Respiratory syncytial virus infection modifies and accelerates pulmonary disease via DC activation and migration.

Jang S, Smit J, Kallal LE, Lukacs NW.

J Leukoc Biol. 2013 Jul;94(1):5-15. doi: 10.1189/jlb.0412195. Epub 2013 Jan 4.


STAT3-mediated IL-17 production by postseptic T cells exacerbates viral immunopathology of the lung.

Mukherjee S, Allen RM, Lukacs NW, Kunkel SL, Carson WF 4th.

Shock. 2012 Nov;38(5):515-23. doi: 10.1097/SHK.0b013e31826f862c.


Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection.

Lee HC, Headley MB, Loo YM, Berlin A, Gale M Jr, Debley JS, Lukacs NW, Ziegler SF.

J Allergy Clin Immunol. 2012 Nov;130(5):1187-1196.e5. doi: 10.1016/j.jaci.2012.07.031. Epub 2012 Sep 13.


Neonatal rhinovirus infection induces mucous metaplasia and airways hyperresponsiveness.

Schneider D, Hong JY, Popova AP, Bowman ER, Linn MJ, McLean AM, Zhao Y, Sonstein J, Bentley JK, Weinberg JB, Lukacs NW, Curtis JL, Sajjan US, Hershenson MB.

J Immunol. 2012 Mar 15;188(6):2894-904. doi: 10.4049/jimmunol.1101391. Epub 2012 Feb 13.


Opposing roles of membrane and soluble forms of the receptor for advanced glycation end products in primary respiratory syncytial virus infection.

Miller AL, Sims GP, Brewah YA, Rebelatto MC, Kearley J, Benjamin E, Keller AE, Brohawn P, Herbst R, Coyle AJ, Humbles AA, Kolbeck R.

J Infect Dis. 2012 Apr 15;205(8):1311-20. doi: 10.1093/infdis/jir826. Epub 2012 Jan 18.


Autophagy-mediated dendritic cell activation is essential for innate cytokine production and APC function with respiratory syncytial virus responses.

Morris S, Swanson MS, Lieberman A, Reed M, Yue Z, Lindell DM, Lukacs NW.

J Immunol. 2011 Oct 15;187(8):3953-61. doi: 10.4049/jimmunol.1100524. Epub 2011 Sep 12.


Evidence for a causal relationship between respiratory syncytial virus infection and asthma.

Wu P, Hartert TV.

Expert Rev Anti Infect Ther. 2011 Sep;9(9):731-45. doi: 10.1586/eri.11.92. Review.


IL-17-induced pulmonary pathogenesis during respiratory viral infection and exacerbation of allergic disease.

Mukherjee S, Lindell DM, Berlin AA, Morris SB, Shanley TP, Hershenson MB, Lukacs NW.

Am J Pathol. 2011 Jul;179(1):248-58. doi: 10.1016/j.ajpath.2011.03.003. Epub 2011 May 3.


Differential pathogenesis of respiratory syncytial virus clinical isolates in BALB/c mice.

Stokes KL, Chi MH, Sakamoto K, Newcomb DC, Currier MG, Huckabee MM, Lee S, Goleniewska K, Pretto C, Williams JV, Hotard A, Sherrill TP, Peebles RS Jr, Moore ML.

J Virol. 2011 Jun;85(12):5782-93. doi: 10.1128/JVI.01693-10. Epub 2011 Apr 6.


Transcriptional regulation by STAT6.

Goenka S, Kaplan MH.

Immunol Res. 2011 May;50(1):87-96. doi: 10.1007/s12026-011-8205-2. Review.


STAT6 expression in multiple cell types mediates the cooperative development of allergic airway disease.

Chapoval SP, Dasgupta P, Smith EP, DeTolla LJ, Lipsky MM, Kelly-Welch AE, Keegan AD.

J Immunol. 2011 Feb 15;186(4):2571-83. doi: 10.4049/jimmunol.1002567. Epub 2011 Jan 17.

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