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Items: 1 to 20 of 112


The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins.

Pettinati I, Brem J, Lee SY, McHugh PJ, Schofield CJ.

Trends Biochem Sci. 2016 Jan 21. pii: S0968-0004(15)00257-1. doi: 10.1016/j.tibs.2015.12.007. [Epub ahead of print] Review.


The structures of the SNM1A and SNM1B/Apollo nuclease domains reveal a potential basis for their distinct DNA processing activities.

Allerston CK, Lee SY, Newman JA, Schofield CJ, McHugh PJ, Gileadi O.

Nucleic Acids Res. 2015 Dec 15;43(22):11047-60. doi: 10.1093/nar/gkv1256. Epub 2015 Nov 17.


Knockout of Drosophila RNase ZL impairs mitochondrial transcript processing, respiration and cell cycle progression.

Xie X, Dubrovsky EB.

Nucleic Acids Res. 2015 Dec 2;43(21):10364-75. doi: 10.1093/nar/gkv1149. Epub 2015 Nov 8.


Functional and Structural Consequences of Damaging Single Nucleotide Polymorphisms in Human Prostate Cancer Predisposition Gene RNASEL.

Datta A, Mazumder MH, Chowdhury AS, Hasan MA.

Biomed Res Int. 2015;2015:271458. doi: 10.1155/2015/271458. Epub 2015 Jul 8.


Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease.

Powell CA, Nicholls TJ, Minczuk M.

Front Genet. 2015 Mar 10;6:79. doi: 10.3389/fgene.2015.00079. eCollection 2015. Review.


Disease variants in genomes of 44 centenarians.

Freudenberg-Hua Y, Freudenberg J, Vacic V, Abhyankar A, Emde AK, Ben-Avraham D, Barzilai N, Oschwald D, Christen E, Koppel J, Greenwald B, Darnell RB, Germer S, Atzmon G, Davies P.

Mol Genet Genomic Med. 2014 Sep;2(5):438-50. doi: 10.1002/mgg3.86. Epub 2014 Jun 15.


tRNA fragments in human health and disease.

Anderson P, Ivanov P.

FEBS Lett. 2014 Nov 28;588(23):4297-304. doi: 10.1016/j.febslet.2014.09.001. Epub 2014 Sep 16. Review.


Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease.

Gerstberger S, Hafner M, Ascano M, Tuschl T.

Adv Exp Med Biol. 2014;825:1-55. doi: 10.1007/978-1-4939-1221-6_1. Review.


Molecular pathways in prostate cancer.

Mazaris E, Tsiotras A.

Nephrourol Mon. 2013 Jul 1;5(3):792-800. doi: 10.5812/numonthly.9430. Epub 2013 Jun 8. Review.


tRNA 3' processing in yeast involves tRNase Z, Rex1, and Rrp6.

Skowronek E, Grzechnik P, Späth B, Marchfelder A, Kufel J.

RNA. 2014 Jan;20(1):115-30. doi: 10.1261/rna.041467.113. Epub 2013 Nov 18.


Strong evidence for a genetic contribution to late-onset Alzheimer's disease mortality: a population-based study.

Kauwe JS, Ridge PG, Foster NL, Cannon-Albright LA.

PLoS One. 2013 Oct 8;8(10):e77087. doi: 10.1371/journal.pone.0077087. eCollection 2013.


A population-based analysis of clustering identifies a strong genetic contribution to lethal prostate cancer.

Nelson Q, Agarwal N, Stephenson R, Cannon-Albright LA.

Front Genet. 2013 Aug 20;4:152. doi: 10.3389/fgene.2013.00152. eCollection 2013.


Partitioning of the nuclear and mitochondrial tRNA 3'-end processing activities between two different proteins in Schizosaccharomyces pombe.

Zhang X, Zhao Q, Huang Y.

J Biol Chem. 2013 Sep 20;288(38):27415-22. doi: 10.1074/jbc.M113.501569. Epub 2013 Aug 8.


Tethered domains and flexible regions in tRNase Z(L), the long form of tRNase Z.

Wilson C, Ramai D, Serjanov D, Lama N, Levinger L, Chang EJ.

PLoS One. 2013 Jul 17;8(7):e66942. doi: 10.1371/journal.pone.0066942. Print 2013.


Developmental roles of Drosophila tRNA processing endonuclease RNase ZL as revealed with a conditional rescue system.

Xie X, Dubrovskaya V, Yacoub N, Walska J, Gleason T, Reid K, Dubrovsky EB.

Dev Biol. 2013 Sep 15;381(2):324-40. doi: 10.1016/j.ydbio.2013.07.005. Epub 2013 Jul 15.


Prostate cancer risk-associated genetic markers and their potential clinical utility.

Xu J, Sun J, Zheng SL.

Asian J Androl. 2013 May;15(3):314-22. doi: 10.1038/aja.2013.42. Epub 2013 Apr 8.


Pairwise shared genomic segment analysis in three Utah high-risk breast cancer pedigrees.

Cai Z, Thomas A, Teerlink C, Farnham JM, Cannon-Albright LA, Camp NJ.

BMC Genomics. 2012 Nov 28;13:676. doi: 10.1186/1471-2164-13-676.


HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG).

Xu J, Lange EM, Lu L, Zheng SL, Wang Z, Thibodeau SN, Cannon-Albright LA, Teerlink CC, Camp NJ, Johnson AM, Zuhlke KA, Stanford JL, Ostrander EA, Wiley KE, Isaacs SD, Walsh PC, Maier C, Luedeke M, Vogel W, Schleutker J, Wahlfors T, Tammela T, Schaid D, McDonnell SK, DeRycke MS, Cancel-Tassin G, Cussenot O, Wiklund F, Grönberg H, Eeles R, Easton D, Kote-Jarai Z, Whittemore AS, Hsieh CL, Giles GG, Hopper JL, Severi G, Catalona WJ, Mandal D, Ledet E, Foulkes WD, Hamel N, Mahle L, Moller P, Powell I, Bailey-Wilson JE, Carpten JD, Seminara D, Cooney KA, Isaacs WB; International Consortium for Prostate Cancer Genetics.

Hum Genet. 2013 Jan;132(1):5-14. doi: 10.1007/s00439-012-1229-4. Epub 2012 Oct 12.


17p12 deletion in breast cancer predicts resistance to neoadjuvant chemotherapy.

Han W, Woo JH, Jeon YK, Yang SJ, Cho J, Ko E, Kim TY, Im SA, Oh DY, Park IA, Hwang KT, Moon HG, Yang KS, Noh DY.

Exp Ther Med. 2011 Sep;2(5):799-804. Epub 2011 Jun 29.


Identification and sequence analysis of metazoan tRNA 3'-end processing enzymes tRNase Zs.

Wang Z, Zheng J, Zhang X, Peng J, Liu J, Huang Y.

PLoS One. 2012;7(9):e44264. doi: 10.1371/journal.pone.0044264. Epub 2012 Sep 4.

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