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Results: 1 to 20 of 212

1.

Modeling of age-dependent amyloid accumulation and γ-secretase inhibition of soluble and insoluble Aβ in a transgenic mouse model of amyloid deposition.

Parkinson J, Ploeger B, Appelkvist P, Bogstedt A, Dillner Bergstedt K, Eketjäll S, Visser SA.

Pharmacol Res Perspect. 2013 Dec;1(2):e00012. doi: 10.1002/prp2.12. Epub 2013 Dec 5.

PMID:
25505567
[PubMed]
Free PMC Article
2.

Neuritin can normalize neural deficits of Alzheimer's disease.

An K, Jung JH, Jeong AY, Kim HG, Jung SY, Lee K, Kim HJ, Kim SJ, Jeong TY, Son Y, Kim HS, Kim JH.

Cell Death Dis. 2014 Nov 13;5:e1523. doi: 10.1038/cddis.2014.478.

PMID:
25393479
[PubMed - in process]
Free PMC Article
3.

Correlations of amyloid-β concentrations between CSF and plasma in acute Alzheimer mouse model.

Cho SM, Kim HV, Lee S, Kim HY, Kim W, Kim TS, Kim DJ, Kim Y.

Sci Rep. 2014 Oct 27;4:6777. doi: 10.1038/srep06777.

PMID:
25345439
[PubMed - in process]
Free PMC Article
4.

Cerebral amyloid angiopathy increases susceptibility to infarction after focal cerebral ischemia in Tg2576 mice.

Milner E, Zhou ML, Johnson AW, Vellimana AK, Greenberg JK, Holtzman DM, Han BH, Zipfel GJ.

Stroke. 2014 Oct;45(10):3064-9. doi: 10.1161/STROKEAHA.114.006078. Epub 2014 Sep 4.

PMID:
25190447
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Spared piriform cortical single-unit odor processing and odor discrimination in the Tg2576 mouse model of Alzheimer's disease.

Xu W, Lopez-Guzman M, Schoen C, Fitzgerald S, Lauer SL, Nixon RA, Levy E, Wilson DA.

PLoS One. 2014 Sep 2;9(9):e106431. doi: 10.1371/journal.pone.0106431. eCollection 2014.

PMID:
25181487
[PubMed - in process]
Free PMC Article
6.

Combined treatment with a BACE inhibitor and anti-Aβ antibody gantenerumab enhances amyloid reduction in APPLondon mice.

Jacobsen H, Ozmen L, Caruso A, Narquizian R, Hilpert H, Jacobsen B, Terwel D, Tanghe A, Bohrmann B.

J Neurosci. 2014 Aug 27;34(35):11621-30. doi: 10.1523/JNEUROSCI.1405-14.2014.

PMID:
25164658
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression.

Simmons DA, Knowles JK, Belichenko NP, Banerjee G, Finkle C, Massa SM, Longo FM.

PLoS One. 2014 Aug 25;9(8):e102136. doi: 10.1371/journal.pone.0102136. eCollection 2014.

PMID:
25153701
[PubMed - in process]
Free PMC Article
8.

Chronic dietary supplementation of 4% figs on the modification of oxidative stress in Alzheimer's disease transgenic mouse model.

Subash S, Essa MM, Al-Asmi A, Al-Adawi S, Vaishnav R.

Biomed Res Int. 2014;2014:546357. doi: 10.1155/2014/546357. Epub 2014 Jun 19.

PMID:
25050360
[PubMed - in process]
Free PMC Article
9.

Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neurons.

Ishii M, Wang G, Racchumi G, Dyke JP, Iadecola C.

J Neurosci. 2014 Jul 2;34(27):9096-106. doi: 10.1523/JNEUROSCI.0872-14.2014.

PMID:
24990930
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Genetic reduction of mammalian target of rapamycin ameliorates Alzheimer's disease-like cognitive and pathological deficits by restoring hippocampal gene expression signature.

Caccamo A, De Pinto V, Messina A, Branca C, Oddo S.

J Neurosci. 2014 Jun 4;34(23):7988-98. doi: 10.1523/JNEUROSCI.0777-14.2014.

PMID:
24899720
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Genetic modulation of soluble Aβ rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease.

Fowler SW, Chiang AC, Savjani RR, Larson ME, Sherman MA, Schuler DR, Cirrito JR, Lesné SE, Jankowsky JL.

J Neurosci. 2014 Jun 4;34(23):7871-85. doi: 10.1523/JNEUROSCI.0572-14.2014. Erratum in: J Neurosci. 2014 Dec 10;34(50):16917.

PMID:
24899710
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer's disease.

Bayer TA, Wirths O.

Acta Neuropathol. 2014 Jun;127(6):787-801. doi: 10.1007/s00401-014-1287-x. Epub 2014 May 7.

PMID:
24803226
[PubMed - in process]
Free PMC Article
13.

Age-related changes of protein SUMOylation balance in the AβPP Tg2576 mouse model of Alzheimer's disease.

Nisticò R, Ferraina C, Marconi V, Blandini F, Negri L, Egebjerg J, Feligioni M.

Front Pharmacol. 2014 Apr 7;5:63. doi: 10.3389/fphar.2014.00063. eCollection 2014.

PMID:
24778618
[PubMed]
Free PMC Article
14.

CB2 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease.

Koppel J, Vingtdeux V, Marambaud P, d'Abramo C, Jimenez H, Stauber M, Friedman R, Davies P.

Mol Med. 2014 Mar 14;20:29-36. doi: 10.2119/molmed.2013.00140.revised.

PMID:
24722782
[PubMed - in process]
Free PMC Article
15.

Disruption of blood-brain barrier in Alzheimer disease pathogenesis.

Kook SY, Seok Hong H, Moon M, Mook-Jung I.

Tissue Barriers. 2013 Apr 1;1(2):e23993. doi: 10.4161/tisb.23993.

PMID:
24665385
[PubMed]
Free PMC Article
16.

Cell-specific blood-brain barrier regulation in health and disease: a focus on hypoxia.

Engelhardt S, Patkar S, Ogunshola OO.

Br J Pharmacol. 2014 Mar;171(5):1210-30. doi: 10.1111/bph.12489. Review.

PMID:
24641185
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

S100A9 knockout decreases the memory impairment and neuropathology in crossbreed mice of Tg2576 and S100A9 knockout mice model.

Kim HJ, Chang KA, Ha TY, Kim J, Ha S, Shin KY, Moon C, Nacken W, Kim HS, Suh YH.

PLoS One. 2014 Feb 25;9(2):e88924. doi: 10.1371/journal.pone.0088924. eCollection 2014.

PMID:
24586443
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Aggregate-depleted brain fails to induce Aβ deposition in a mouse model of Alzheimer's disease.

Duran-Aniotz C, Morales R, Moreno-Gonzalez I, Hu PP, Fedynyshyn J, Soto C.

PLoS One. 2014 Feb 12;9(2):e89014. doi: 10.1371/journal.pone.0089014. eCollection 2014.

PMID:
24533166
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Association between amylin and amyloid-β peptides in plasma in the context of apolipoprotein E4 allele.

Qiu WQ, Wallack M, Dean M, Liebson E, Mwamburi M, Zhu H.

PLoS One. 2014 Feb 10;9(2):e88063. doi: 10.1371/journal.pone.0088063. eCollection 2014.

PMID:
24520345
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

CB₂ receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease.

Koppel J, Vingtdeux V, Marambaud P, d'Abramo C, Jimenez H, Stauber M, Friedman R, Davies P.

Mol Med. 2013 Nov 8;19:357-64. doi: 10.2119/molmed.2013.00140. Erratum in: Mol Med. 2014;20():37. Corrected and republished in: Mol Med. 2014;20:29-36.

PMID:
24408112
[PubMed - indexed for MEDLINE]
Free PMC Article
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