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Results: 20

1.

Transformation of polarized epithelial cells by apical mistrafficking of epiregulin.

Singh B, Bogatcheva G, Washington MK, Coffey RJ.

Proc Natl Acad Sci U S A. 2013 May 28;110(22):8960-5. doi: 10.1073/pnas.1305508110. Epub 2013 May 13.

PMID:
23671122
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Increased epidermal growth factor-like ligands are associated with elevated vascular nicotinamide adenine dinucleotide phosphate oxidase in a primate model of atherosclerosis.

Stanic B, Pandey D, Fulton DJ, Miller FJ Jr.

Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2452-60. doi: 10.1161/ATVBAHA.112.256107. Epub 2012 Aug 9.

PMID:
22879585
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Inhibition of phosphodiesterase-4 (PDE4) activity triggers luminal apoptosis and AKT dephosphorylation in a 3-D colonic-crypt model.

Tsunoda T, Ota T, Fujimoto T, Doi K, Tanaka Y, Yoshida Y, Ogawa M, Matsuzaki H, Hamabashiri M, Tyson DR, Kuroki M, Miyamoto S, Shirasawa S.

Mol Cancer. 2012 Jul 25;11:46. doi: 10.1186/1476-4598-11-46.

PMID:
22830422
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells.

Müller KM, Tveteraas IH, Aasrum M, Ødegård J, Dawood M, Dajani O, Christoffersen T, Sandnes DL.

BMC Cancer. 2011 Oct 2;11:421. doi: 10.1186/1471-2407-11-421.

PMID:
21961726
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Regulation of homeostasis and oncogenesis in the intestinal epithelium by Ras.

Velho S, Haigis KM.

Exp Cell Res. 2011 Nov 15;317(19):2732-9. doi: 10.1016/j.yexcr.2011.06.002. Epub 2011 Jun 17. Review.

PMID:
21741971
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.

Tsunoda T, Takashima Y, Fujimoto T, Koyanagi M, Yoshida Y, Doi K, Tanaka Y, Kuroki M, Sasazuki T, Shirasawa S.

Neoplasia. 2010 May;12(5):397-404.

PMID:
20454511
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway.

Cardó-Vila M, Giordano RJ, Sidman RL, Bronk LF, Fan Z, Mendelsohn J, Arap W, Pasqualini R.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5118-23. doi: 10.1073/pnas.0915146107. Epub 2010 Feb 26.

PMID:
20190183
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Transcriptomic analysis of pathways regulated by toll-like receptor 4 in a murine model of chronic pulmonary inflammation and carcinogenesis.

Bauer AK, Fostel J, Degraff LM, Rondini EA, Walker C, Grissom SF, Foley J, Kleeberger SR.

Mol Cancer. 2009 Nov 19;8:107. doi: 10.1186/1476-4598-8-107.

PMID:
19925653
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Molecular characterization of lung dysplasia induced by c-Raf-1.

Rohrbeck A, Müller VS, Borlak J.

PLoS One. 2009 May 20;4(5):e5637. doi: 10.1371/journal.pone.0005637.

PMID:
19529782
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer.

Rodilla V, Villanueva A, Obrador-Hevia A, Robert-Moreno A, Fernández-Majada V, Grilli A, López-Bigas N, Bellora N, Albà MM, Torres F, Duñach M, Sanjuan X, Gonzalez S, Gridley T, Capella G, Bigas A, Espinosa L.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6315-20. doi: 10.1073/pnas.0813221106. Epub 2009 Mar 26.

PMID:
19325125
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

TGF-beta receptor inactivation and mutant Kras induce intestinal neoplasms in mice via a beta-catenin-independent pathway.

Trobridge P, Knoblaugh S, Washington MK, Munoz NM, Tsuchiya KD, Rojas A, Song X, Ulrich CM, Sasazuki T, Shirasawa S, Grady WM.

Gastroenterology. 2009 May;136(5):1680-8.e7. doi: 10.1053/j.gastro.2009.01.066. Epub 2009 Feb 4.

PMID:
19208363
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Intratumoral epiregulin is a marker of advanced disease in non-small cell lung cancer patients and confers invasive properties on EGFR-mutant cells.

Zhang J, Iwanaga K, Choi KC, Wislez M, Raso MG, Wei W, Wistuba II, Kurie JM.

Cancer Prev Res (Phila). 2008 Aug;1(3):201-7. doi: 10.1158/1940-6207.CAPR-08-0014. Epub 2008 Mar 31.

PMID:
19138957
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Lapatinib resistance in HCT116 cells is mediated by elevated MCL-1 expression and decreased BAK activation and not by ERBB receptor kinase mutation.

Martin AP, Miller A, Emad L, Rahmani M, Walker T, Mitchell C, Hagan MP, Park MA, Yacoub A, Fisher PB, Grant S, Dent P.

Mol Pharmacol. 2008 Sep;74(3):807-22. doi: 10.1124/mol.108.047365. Epub 2008 Jun 10.

PMID:
18544666
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The kinetics of the hydrogen/deuterium exchange of epidermal growth factor receptor ligands.

Iloro I, Narváez D, Guillén N, Camacho CM, Guillén L, Cora E, Pastrana-Ríos B.

Biophys J. 2008 May 15;94(10):4041-55. doi: 10.1529/biophysj.107.125856. Epub 2008 Jan 16.

PMID:
18199660
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Selective Raf inhibition in cancer therapy.

Khazak V, Astsaturov I, Serebriiskii IG, Golemis EA.

Expert Opin Ther Targets. 2007 Dec;11(12):1587-609. Review. Erratum in: Expert Opin Ther Targets. 2009 Sep;13(9):1135.

PMID:
18020980
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Synergistic inhibition of growth of lung carcinomas by antagonists of growth hormone-releasing hormone in combination with docetaxel.

Hohla F, Schally AV, Szepeshazi K, Varga JL, Buchholz S, Köster F, Heinrich E, Halmos G, Rick FG, Kannadka C, Datz C, Kanashiro CA.

Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14513-8. Epub 2006 Sep 18.

PMID:
16983095
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A role for K-ras in conferring resistance to the MEK inhibitor, CI-1040.

Wang Y, Van Becelaere K, Jiang P, Przybranowski S, Omer C, Sebolt-Leopold J.

Neoplasia. 2005 Apr;7(4):336-47.

PMID:
15967111
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Epiregulin is not essential for development of intestinal tumors but is required for protection from intestinal damage.

Lee D, Pearsall RS, Das S, Dey SK, Godfrey VL, Threadgill DW.

Mol Cell Biol. 2004 Oct;24(20):8907-16.

PMID:
15456865
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Dermatitis due to epiregulin deficiency and a critical role of epiregulin in immune-related responses of keratinocyte and macrophage.

Shirasawa S, Sugiyama S, Baba I, Inokuchi J, Sekine S, Ogino K, Kawamura Y, Dohi T, Fujimoto M, Sasazuki T.

Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13921-6. Epub 2004 Sep 13.

PMID:
15365177
[PubMed - indexed for MEDLINE]
Free PMC Article

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