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Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers.

Ward AK, Mellor P, Smith SE, Kendall S, Just NA, Vizeacoumar FS, Sarker S, Phillips Z, Alvi R, Saxena A, Vizeacoumar FJ, Carlsen SA, Anderson DH.

Breast Cancer Res. 2016 Jan 25;18(1):12. doi: 10.1186/s13058-016-0672-x.


Altered Expression of Endoplasmic Reticulum Stress Associated Genes in Hippocampus of Learned Helpless Rats: Relevance to Depression Pathophysiology.

Timberlake MA 2nd, Dwivedi Y.

Front Pharmacol. 2016 Jan 12;6:319. doi: 10.3389/fphar.2015.00319. eCollection 2015.


Why is start codon selection so precise in eukaryotes?

Asano K.

Translation (Austin). 2014 Mar 12;2(1):e28387. doi: 10.4161/trla.28387. eCollection 2014. Review.


Naïve T Cell Homeostasis Regulated by Stress Responses and TCR Signaling.

Kamimura D, Atsumi T, Stofkova A, Nishikawa N, Ohki T, Suzuki H, Katsunuma K, Jiang JJ, Bando H, Meng J, Sabharwal L, Ogura H, Hirano T, Arima Y, Murakami M.

Front Immunol. 2015 Dec 17;6:638. doi: 10.3389/fimmu.2015.00638. eCollection 2015. Review.


Inadequate fine-tuning of protein synthesis and failure of amino acid homeostasis following inhibition of the ATPase VCP/p97.

Parzych K, Chinn TM, Chen Z, Loaiza S, Porsch F, Valbuena GN, Kleijnen MF, Karadimitris A, Gentleman E, Keun HC, Auner HW.

Cell Death Dis. 2015 Dec 31;6:e2031. doi: 10.1038/cddis.2015.373.


An inhibitor of HIV-1 protease modulates constitutive eIF2α dephosphorylation to trigger a specific integrated stress response.

De Gassart A, Bujisic B, Zaffalon L, Decosterd LA, Di Micco A, Frera G, Tallant R, Martinon F.

Proc Natl Acad Sci U S A. 2016 Jan 12;113(2):E117-26. doi: 10.1073/pnas.1514076113. Epub 2015 Dec 29.


KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.

Chattopadhyay N, Berger AJ, Koenig E, Bannerman B, Garnsey J, Bernard H, Hales P, Maldonado Lopez A, Yang Y, Donelan J, Jordan K, Tirrell S, Stringer B, Xia C, Hather G, Galvin K, Manfredi M, Rhodes N, Amidon B.

PLoS One. 2015 Dec 28;10(12):e0144825. doi: 10.1371/journal.pone.0144825. eCollection 2015.


Targeting the indoleamine 2,3-dioxygenase pathway in cancer.

Moon YW, Hajjar J, Hwu P, Naing A.

J Immunother Cancer. 2015 Dec 15;3:51. doi: 10.1186/s40425-015-0094-9. eCollection 2015. Review.


Maize reas1 Mutant Stimulates Ribosome Use Efficiency and Triggers Distinct Transcriptional and Translational Responses.

Qi W, Zhu J, Wu Q, Wang Q, Li X, Yao D, Jin Y, Wang G, Wang G, Song R.

Plant Physiol. 2016 Feb;170(2):971-88. doi: 10.1104/pp.15.01722. Epub 2015 Dec 8.


Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS.

Sun S, Sun Y, Ling SC, Ferraiuolo L, McAlonis-Downes M, Zou Y, Drenner K, Wang Y, Ditsworth D, Tokunaga S, Kopelevich A, Kaspar BK, Lagier-Tourenne C, Cleveland DW.

Proc Natl Acad Sci U S A. 2015 Dec 15;112(50):E6993-7002. doi: 10.1073/pnas.1520639112. Epub 2015 Nov 30.


β cell ER stress and the implications for immunogenicity in type 1 diabetes.

Marré ML, James EA, Piganelli JD.

Front Cell Dev Biol. 2015 Oct 27;3:67. doi: 10.3389/fcell.2015.00067. eCollection 2015. Review.


IRE1α-XBP1 is a novel branch in the transcriptional regulation of Ucp1 in brown adipocytes.

Asada R, Kanemoto S, Matsuhisa K, Hino K, Cui M, Cui X, Kaneko M, Imaizumi K.

Sci Rep. 2015 Nov 16;5:16580. doi: 10.1038/srep16580.


A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells.

Gowen BG, Chim B, Marceau CD, Greene TT, Burr P, Gonzalez JR, Hesser CR, Dietzen PA, Russell T, Iannello A, Coscoy L, Sentman CL, Carette JE, Muljo SA, Raulet DH.

Elife. 2015 Nov 13;4. pii: e08474. doi: 10.7554/eLife.08474.


Endoplasmic Reticulum Stress Signaling in Plant Immunity--At the Crossroad of Life and Death.

Kørner CJ, Du X, Vollmer ME, Pajerowska-Mukhtar KM.

Int J Mol Sci. 2015 Nov 5;16(11):26582-98. doi: 10.3390/ijms161125964. Review.


GCN2 sustains mTORC1 suppression upon amino acid deprivation by inducing Sestrin2.

Ye J, Palm W, Peng M, King B, Lindsten T, Li MO, Koumenis C, Thompson CB.

Genes Dev. 2015 Nov 15;29(22):2331-6. doi: 10.1101/gad.269324.115. Epub 2015 Nov 5.


In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse.

Alavi MV, Chiang WC, Kroeger H, Yasumura D, Matthes MT, Iwawaki T, LaVail MM, Gould DB, Lin JH.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6961-70. doi: 10.1167/iovs.15-16969.


Inhibition of autophagy exerts anti-colon cancer effects via apoptosis induced by p53 activation and ER stress.

Sakitani K, Hirata Y, Hikiba Y, Hayakawa Y, Ihara S, Suzuki H, Suzuki N, Serizawa T, Kinoshita H, Sakamoto K, Nakagawa H, Tateishi K, Maeda S, Ikenoue T, Kawazu S, Koike K.

BMC Cancer. 2015 Oct 24;15:795. doi: 10.1186/s12885-015-1789-5.


NRF2 regulates serine biosynthesis in non-small cell lung cancer.

DeNicola GM, Chen PH, Mullarky E, Sudderth JA, Hu Z, Wu D, Tang H, Xie Y, Asara JM, Huffman KE, Wistuba II, Minna JD, DeBerardinis RJ, Cantley LC.

Nat Genet. 2015 Dec;47(12):1475-81. doi: 10.1038/ng.3421. Epub 2015 Oct 19.


Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma.

Palam LR, Gore J, Craven KE, Wilson JL, Korc M.

Cell Death Dis. 2015 Oct 15;6:e1913. doi: 10.1038/cddis.2015.264.


The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health.

Saikia M, Hatzoglou M.

J Biol Chem. 2015 Dec 11;290(50):29761-8. doi: 10.1074/jbc.R115.694661. Epub 2015 Oct 13. Review.

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